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Painkiller Medications - Page 2

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
nortriptyline Off-label 6.7 126 reviews for nortriptyline to treat Pain
Rx N N X
Generic name:
nortriptyline systemic
Drug class:
tricyclic antidepressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
celecoxib 6.7 124 reviews for celecoxib to treat Pain
Rx C N
Generic name:
celecoxib systemic
Brand name:
Celebrex
Drug class:
cox-2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Celebrex 6.8 105 reviews for Celebrex to treat Pain
Rx C N
Generic name:
celecoxib systemic
Drug class:
cox-2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
naproxen 6.2 105 reviews for naproxen to treat Pain
Rx/OTC C N X
Generic name:
naproxen systemic
Brand names:
Aleve, Naprosyn, Aflaxen, All Day Pain Relief, All Day Relief, Anaprox-DS, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan
Drug class:
Nonsteroidal anti-inflammatory drugs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Hysingla ER 4.1 98 reviews for Hysingla ER to treat Pain
Rx C 2 X
Generic name:
hydrocodone systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
meperidine 9.5 94 reviews for meperidine to treat Pain
Rx C 2 X
Generic name:
meperidine systemic
Brand names:
Demerol, Meperitab
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
aspirin / caffeine 5.8 88 reviews for aspirin / caffeine to treat Pain
OTC N N X
Generic name:
aspirin / caffeine systemic
Brand names:
Alka-Seltzer Wake-Up Call!, Anacin, Anacin Max Strength, Back & Body Extra Strength, Bayer Extra Strength Back & Body, BC Arthritis, BC Fast Pain Relief, BC Original, Cope, P-A-C, P-A-C Analgesic
Drug class:
analgesic combinations
For consumers:
dosage, interactions, side effects
duloxetine Off-label 7.1 87 reviews for duloxetine to treat Pain
Rx C N X
Generic name:
duloxetine systemic
Drug class:
serotonin-norepinephrine reuptake inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Flector Patch 7.2 84 reviews for Flector Patch to treat Pain
Rx C N
Generic name:
diclofenac topical
Drug class:
topical non-steroidal anti-inflammatories
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
bupivacaine liposome 5.7 76 reviews for bupivacaine liposome to treat Pain
Rx C N
Generic name:
bupivacaine liposome systemic
Brand name:
Exparel
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
Butrans 6.7 76 reviews for Butrans to treat Pain
Rx C 3 X
Generic name:
buprenorphine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
hydrocodone / ibuprofen 8.6 74 reviews for hydrocodone / ibuprofen to treat Pain
Rx C 2 X
Generic name:
hydrocodone / ibuprofen systemic
Drug class:
narcotic analgesic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Nucynta ER 7.1 73 reviews for Nucynta ER to treat Pain
Rx C 2 X
Generic name:
tapentadol systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
BC Original 5.6 71 reviews for BC Original to treat Pain
OTC N N X
Generic name:
aspirin / caffeine systemic
Drug class:
analgesic combinations
For consumers:
dosage, interactions, side effects
Demerol 9.6 70 reviews for Demerol to treat Pain
Rx C 2 X
Generic name:
meperidine systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Exparel 5.6 69 reviews for Exparel to treat Pain
Rx C N
Generic name:
bupivacaine liposome systemic
Drug class:
local injectable anesthetics
For consumers:
dosage, interactions, side effects
capsaicin 4.8 65 reviews for capsaicin to treat Pain
Rx/OTC B N
Generic name:
capsaicin topical
Brand names:
Aspercreme Warming Pain Relief Patch, Axsain, Capsagel Extra Strength, Capsin, Capzasin, Capzasin-HP, Capzasin-P, Capzasin Back and Body, Castiva Warming, Menthac Arthritis Cream with Capsaicin, Qutenza, Salonpas-Hot, Sloan's Liniment, Theragen HP, Zostrix, Zostrix Diabetic Foot Pain, Zostrix Neuropathy, Zostrix Sports
Drug class:
miscellaneous topical agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
acetaminophen 6.0 61 reviews for acetaminophen to treat Pain
Rx/OTC C N X
Generic name:
acetaminophen systemic
Brand names:
Tylenol, Paracetamol, Tylenol Arthritis Pain, Tylenol 8 Hour, Altenol, Arthritis Pain Relief, Cetafen, Dolono, Feverall, Mapap, Vitapap, 7T Gummy ES Chewable Tablets, Acephen, Actamin, Aminofen, Anacin Aspirin Free, Apra, Aurophen, Children's Silapap, Children's Tylenol, Febrol Solution, Genapap, Genebs, Infant's Tylenol, Jr. Tylenol, Leader 8 Hour Pain Reliever, M-Pap, Mapap Arthritis Pain, Nortemp Children's, Pharbetol, Silapap Childrens, Tactinal, Tempra Quicklets, Tycolene, Tylophen
Drug class:
miscellaneous analgesics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Sprix 7.3 57 reviews for Sprix to treat Pain
Rx C N X
Generic name:
ketorolac systemic
Drug class:
Nonsteroidal anti-inflammatory drugs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
acetaminophen / tramadol 6.9 55 reviews for acetaminophen / tramadol to treat Pain
Rx C 4 X
Generic name:
acetaminophen / tramadol systemic
Brand name:
Ultracet
Drug class:
narcotic analgesic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ibuprofen 7.7 53 reviews for ibuprofen to treat Pain
Rx/OTC C N X
Generic name:
ibuprofen systemic
Brand names:
Advil, Motrin, Advil Liqui-Gels, Motrin IB, Proprinal, A-G Profen, Addaprin, Advil Children's, Advil Infant's Concentrated Drops, Advil Junior Strength, Advil Migraine, Caldolor, Children's Motrin, Genpril, IBU-200, Midol IB, Motrin Childrens, Motrin Infant Drops, Motrin Junior Strength, Nuprin
Drug class:
Nonsteroidal anti-inflammatory drugs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
etodolac 7.5 52 reviews for etodolac to treat Pain
Rx C N X
Generic name:
etodolac systemic
Drug class:
Nonsteroidal anti-inflammatory drugs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Voltaren 7.5 52 reviews for Voltaren to treat Pain
Rx D N X
Generic name:
diclofenac systemic
Drug class:
Nonsteroidal anti-inflammatory drugs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
butorphanol 8.4 51 reviews for butorphanol to treat Pain
Rx C 4 X
Generic name:
butorphanol systemic
Drug class:
Opioids (narcotic analgesics)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
codeine 7.2 44 reviews for codeine to treat Pain
Rx C 2 X
Generic name:
codeine systemic
Drug class:
Opioids (narcotic analgesics), antitussives
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information

Frequently asked questions

View more FAQ

Topics under Pain

Alternative treatments for Pain

The following products are considered to be alternative treatments or natural remedies for Pain. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However, there may be historical, cultural or anecdotal evidence linking their use to the treatment of Pain.

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.