Skip to Content

Flector Patch Side Effects

Generic Name: diclofenac topical

Note: This document contains side effect information about diclofenac topical. Some of the dosage forms listed on this page may not apply to the brand name Flector Patch.

In Summary

Common side effects of Flector Patch include: increased liver enzymes. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to diclofenac topical: topical application cream, topical application gel/jelly, topical application patch extended release, topical application solution, topical application spray

Along with its needed effects, diclofenac topical (the active ingredient contained in Flector Patch) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking diclofenac topical:

More Common

  • Application site reactions, including skin rash, pain, tingling, or burning sensation
  • flu-like syndrome (body ache, headache, fever, with or without chills)
  • itching skin

Less Common or Rare

  • Blood in the urine
  • cough
  • dry, itching, or burning eyes
  • eye pain
  • headaches, including migraines
  • increased sensitivity of the skin
  • nasal congestion
  • pain or tenderness around the eyes and cheekbones
  • redness of the skin
  • redness or swelling of the eyes
  • skin rash other than at the application site
  • sore throat
  • tightness in the chest
  • troubled breathing
  • ulcers or sores on the skin, other than at the application site

Some side effects of diclofenac topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

  • Burning skin
  • dry skin
  • scaly skin
  • thickened skin
  • tingling skin

Less Common

For Healthcare Professionals

Applies to diclofenac topical: topical cream, topical film extended release, topical gel, topical kit, topical solution


The most frequently reported side effects were application site reactions.[Ref]


Very common (10% or more): Dryness (up to 32%)

Common (1% to 10%): Dermatitis, burning sensation, pruritus, exfoliation, erythema, pain, induration, rash, scabbing, contusion, inflammation, irritation, itching, tingling, blistering, localized paresthesia

Frequency not reported: Vesicles, papules, localized hair discoloration, vasodilation, purpuric rash, atrophy[Ref]


Common (1% to 10%): Contact dermatitis, eczema, dry skin, rash, scaly rash, skin hypertrophy, skin ulcer, vesiculobullous rash, exfoliation, urticaria, acne, alopecia, skin nodule

Uncommon (0.1% to 1%): Face edema, maculopapular rash, photosensitivity reaction, seborrhea

Rare (0.01% to 0.1%): Bullous dermatitis

Very rare (less than 0.01%): Pustular rash

Frequency not reported: Skin hypertrophy[Ref]


Common (1% to 10%): Hypertension

Uncommon (0.1% to 1%): Hemorrhage

Postmarketing reports: Palpitation, cardiovascular disorder, blood pressure increased[Ref]


Common (1% to 10%): Abdominal pain, diarrhea, dyspepsia, halitosis, nausea, flatulence, constipation

Very rare (less than 0.01%): Gastrointestinal hemorrhage

Frequency not reported: Upper abdominal pain

Postmarketing reports: Dry mouth, gastroenteritis, mouth ulceration, rectal hemorrhage, ulcerative stomatitis, lip swelling, swollen tongue[Ref]

Nervous system

Common (1% to 10%): Headache, migraine, hypokinesia, dysgeusia, somnolence, hypertonia, hyperesthesia, paresthesia

Postmarketing reports: Dizziness, drowsiness, lethargy, taste perversion[Ref]


Common (1% to 10%): Creatinine increased

Very rare (less than 0.01%): Renal failure[Ref]


Common (1% to 10%): SGOT increased, SGPT increased[Ref]


Common (1% to 10%): Hypercholesterolemia, hyperglycemia

Postmarketing reports: Appetite decreased[Ref]


Common (1% to 10%): Back pain, neck pain, arthralgia, arthrosis, myalgia

Postmarketing reports: Leg cramps[Ref]


Common (1% to 10%): Eye pain, conjunctivitis

Uncommon (0.1% to 1%): Lacrimation disorder

Postmarketing reports: Abnormal vision, blurred vision, cataract, eye disorder[Ref]


Common (1% to 10%): Asthma, dyspnea, pharyngitis, pneumonia, rhinitis, sinusitis, sinus congestion

Postmarketing reports: Laryngismus, laryngitis[Ref]


Common (1% to 10%): Accidental injury, asthenia, chest pain, flu-like syndrome, infection, pain, creatine phosphokinase increased, edema

Postmarketing reports: Lack of drug effect, body odor, ear pain[Ref]


Common (1% to 10%): Skin carcinoma[Ref]


Common (1% to 10%): Hematuria, urinary tract infection[Ref]


Common (1% to 10%): Allergic reaction[Ref]


Postmarketing reports: Depression[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Flector Patch (diclofenac topical)." Actavis U.S. (Alpharma USPD), Owings Mills, MD.

4. "Product Information. Solaraze (diclofenac topical)" SkyePharma, San Diego, CA.

5. "Product Information. Pennsaid (diclofenac topical)." Horizon Pharma USA Inc, Northbrook, IL.

6. "Product Information. Voltaren Topical (diclofenac topical)." Endo Laboratories LLC, Chadds Ford, PA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.