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Aspirin / Caffeine Dosage

Medically reviewed by Drugs.com. Last updated on Aug 16, 2023.

Applies to the following strengths: 400 mg-32 mg; 845 mg-65 mg; 500 mg-32 mg; 1000 mg-65 mg; 421 mg-32 mg; 500 mg-32.5 mg; 500 mg-65 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Fever

Aspirin 325 to 650 mg orally every 4 hours or Aspirin 500 to 1000 mg orally every 6 hours with Caffeine (in doses up to 65 mg) as needed
Maximum number of daily doses: 4
Maximum daily dose: Aspirin: 4000 mg

Comments:


Uses: For the temporary relief of minor aches and pains due to headache, toothache, muscular aches, backache, arthritis, and menstrual cramps; for the temporary relief of pain and fever due to colds.

Usual Adult Dose for Pain

Aspirin 325 to 650 mg orally every 4 hours or Aspirin 500 to 1000 mg orally every 6 hours with Caffeine (in doses up to 65 mg) as needed
Maximum number of daily doses: 4
Maximum daily dose: Aspirin: 4000 mg

Comments:


Uses: For the temporary relief of minor aches and pains due to headache, toothache, muscular aches, backache, arthritis, and menstrual cramps; for the temporary relief of pain and fever due to colds.

Usual Pediatric Dose for Fever

12 years or older:

Aspirin 325 to 650 mg orally every 4 hours or Aspirin 500 to 1000 mg orally every 6 hours with Caffeine (in doses up to 65 mg) as needed
Maximum number of daily doses: 4
Maximum daily dose: Aspirin: 4000 mg

Comments:


Uses: For the temporary relief of minor aches and pains due to headache, toothache, muscular aches, backache, arthritis, and menstrual cramps; for the temporary relief of pain and fever due to colds.

Usual Pediatric Dose for Pain

12 years or older:

Aspirin 325 to 650 mg orally every 4 hours or Aspirin 500 to 1000 mg orally every 6 hours with Caffeine (in doses up to 65 mg) as needed
Maximum number of daily doses: 4
Maximum daily dose: Aspirin: 4000 mg

Comments:


Uses: For the temporary relief of minor aches and pains due to headache, toothache, muscular aches, backache, arthritis, and menstrual cramps; for the temporary relief of pain and fever due to colds.

Renal Dose Adjustments

Use with caution; routine aspirin use is not recommended in patients with severe renal impairment (CrCl less than 10 mL/minute) due to an increased risk of salicylate toxicity

Liver Dose Adjustments

Use with caution; routine aspirin use is not recommended in patients with severe hepatic impairment due to the potential for increased risk of clinically significant bleeding and other adverse effects.

Dose Adjustments

Elderly: Use with caution due to increased risk of adverse events; consider the maximal dose in elderly patients to be less than that the adult maximal dose

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:
Tablets: Take orally with a full glass of water

Effervescent Tablets: Fully dissolve tablets in 16 ounces of water and drink

Powder:


General:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.