Aspirin/caffeine Interactions
There are 463 drugs known to interact with aspirin/caffeine, along with 18 disease interactions, and 6 alcohol/food interactions. Of the total drug interactions, 66 are major, 345 are moderate, and 52 are minor.
- View all 463 medications that may interact with aspirin/caffeine
- View aspirin/caffeine alcohol/food interactions (6)
- View aspirin/caffeine disease interactions (18)
Most frequently checked interactions
View interaction reports for aspirin / caffeine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Advair Diskus (fluticasone / salmeterol)
- Advair HFA (fluticasone / salmeterol)
- Aleve (naproxen)
- Allegra (fexofenadine)
- Benadryl (diphenhydramine)
- BuSpar (buspirone)
- Claritin (loratadine)
- CoQ10 (ubiquinone)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Klonopin (clonazepam)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Nexium (esomeprazole)
- Paracetamol (acetaminophen)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Tylenol Extra Strength (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B6 (pyridoxine)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
Aspirin/caffeine alcohol/food interactions
There are 6 alcohol/food interactions with aspirin / caffeine.
Aspirin/caffeine disease interactions
There are 18 disease interactions with aspirin / caffeine which include:
- coagulation
- cardiac disease
- hypertension
- psychiatric disorders
- PUD
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- cardiotoxicity
- liver disease
- renal dysfunction
- seizure disorders
- GERD
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
Report options
More about aspirin / caffeine
- aspirin/caffeine consumer information
- Compare alternatives
- Reviews (311)
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Naproxen
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.