Aspirin/caffeine Interactions
There are 464 drugs known to interact with aspirin/caffeine, along with 18 disease interactions, and 6 alcohol/food interactions. Of the total drug interactions, 66 are major, 346 are moderate, and 52 are minor.
- View all 464 medications that may interact with aspirin/caffeine
- View aspirin/caffeine alcohol/food interactions (6)
- View aspirin/caffeine disease interactions (18)
Most frequently checked interactions
View interaction reports for aspirin / caffeine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Adderall (amphetamine / dextroamphetamine)
- Aleve (naproxen)
- Aleve (naproxen)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Crestor (rosuvastatin)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Succinate ER (metoprolol)
- Nexium (esomeprazole)
- Nexium (esomeprazole)
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
- Wellbutrin XL (bupropion)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Aspirin/caffeine alcohol/food interactions
There are 6 alcohol/food interactions with aspirin / caffeine.
Aspirin/caffeine disease interactions
There are 18 disease interactions with aspirin / caffeine which include:
- coagulation
- cardiac disease
- hypertension
- psychiatric disorders
- PUD
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- cardiotoxicity
- liver disease
- renal dysfunction
- seizure disorders
- GERD
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
Report options
More about aspirin / caffeine
- aspirin/caffeine consumer information
- Compare alternatives
- Reviews (311)
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Ibuprofen
Ibuprofen (Advil, Motrin) treats minor aches and pains caused by the common cold, headaches ...
Paracetamol
Paracetamol (Panadol, Calpol, Alvedon) is a widely used over-the-counter painkiller and fever ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Tylenol
Tylenol is a pain reliever and a fever reducer used to treat many conditions such as headaches ...
Advil
Advil (ibuprofen) reduces fever, pain and inflammation caused by headaches, toothaches, arthritis ...
Aleve
Aleve is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. Learn ...
Anacin
Anacin (aspirin and caffeine) is used to treat headaches, arthritis, backache, colds, and fever ...
Ketoprofen
Ketoprofen systemic is used for back pain, fever, frozen shoulder, gout, acute, osteoarthritis ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.