Hydrocodone/ibuprofen Interactions
There are 873 drugs known to interact with hydrocodone/ibuprofen, along with 27 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 305 are major, 558 are moderate, and 10 are minor.
- View all 873 medications that may interact with hydrocodone/ibuprofen
- View hydrocodone/ibuprofen alcohol/food interactions (2)
- View hydrocodone/ibuprofen disease interactions (27)
Most frequently checked interactions
View interaction reports for hydrocodone / ibuprofen and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Lamictal (lamotrigine)
- Lasix (furosemide)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Plavix (clopidogrel)
- ProAir HFA (albuterol)
- Singulair (montelukast)
- Symbicort (budesonide / formoterol)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Hydrocodone/ibuprofen alcohol/food interactions
There are 2 alcohol/food interactions with hydrocodone / ibuprofen.
Hydrocodone/ibuprofen disease interactions
There are 27 disease interactions with hydrocodone / ibuprofen which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- PKU
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
- arrhythmias
- biliary tract disease
Report options
QR code containing a link to this page
More about hydrocodone / ibuprofen
- hydrocodone/ibuprofen consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (74)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: narcotic analgesic combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
