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User Reviews for Hysingla ER to treat Pain

Hysingla ER has an average rating of 4.1 out of 10 from a total of 88 ratings for the treatment of Pain. 26% of reviewers reported a positive effect, while 57% reported a negative effect.

Hysingla ER Rating Summary

4.1/10 average rating

88 ratings from 95 user reviews.

Compare all 1432 medications used in the treatment of Pain.

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Reviews for Hysingla ER

Rockpaperscissors July 26, 2015

“I've had a really good experience with Hysingla ER. I have had dibilitating Sacrio, SI Joint, sciatic nerve pain for 6 years. Tried chiropractic care, acupuncture, massage therapy, physical therapy, injections, electro shock therapy, and norco 10/325 4x per day for the last 4 years. I did get some relief, but not enough to make my daily life enjoyable. It's been a struggle with pain daily. Especially with three small children. Two months ago, my pain dr recommended Hysingla ER to me (as a last resort before surgery) and I decided to give it a shot. I started at 20mg, 4 weeks later 30mg, 4 weeks later 40mg. I can't believe the difference of my life since starting Hysingla!! I can take long walks again! I can grocery shop again!”

10 / 10
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Whoknew? March 27, 2016

“I have had chronic lower back pain/degenerative disc disease for over 25 years, along with an L5 S1 diskectomy, my pain and my condition continue to get worse with time. In the past I have been on Oxycodone, Hydrocodone, Fentanyl, and just most recently, Oxycontin 30 mg time release, did not like them at all. Even more recently I was prescribed Hysingla 80mg time release. I have been taking it for two days now and I am amazed at how I feel when I wake up! No pain, and slight withdraw, at which point I take a 10 mg oxycodone for breakthrough pain. It's been forever since I have woken up happy. Don't notice any side effects yet, can say, that it certainly does not last he 24 hrs.... more like 12-14, and takes a few hours to start working...”

8 / 10
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Krissy · Taken for 1 to 6 months June 13, 2019

“Tried morphine and Percocet for severe intractable pain from injuries and surgery. Hysingla then prescribed as those did not help. Hysingla did nothing for my pain and also made my head feel swimmy and it’s very constipating like severely. Dr tried Norco and I’m finally pain free most of the day now first time in years. I really can’t say why hysingla didn’t work because norco Is the same ingredient but it didn’t work for me and norco really does work for me. Like amazingly. And I’ve never had to step up dosage nor ever had addiction or withdrawals to pain medication. (Only cymbalta for me was highly addictive and took me over a year to get off of it. Withdrawal was severe. Strange because they say opioids are not safe but for me they are and antidepressants were not. Very strange.)”

2 / 10
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Finny August 24, 2018

“I’ve had 9 surgeries since 2003. One total shoulder replacement that was done incorrectly and need to be redone. Failed shoulder cuff other arm so that causes constant pain. Total hip total knee. Three back surgeries! The last one in 2015 Spinal Fusion. I am in constant pain. I’ve tried everything. Injections,PT , burning of the nerves nothing helps! Pain doc has me on Hysingla 40 mg does nothing! Due to terrible upper gut ulcers from upper bowel obstruction ( that was because when I had an emergency splenectomy the surgeon tied a knot in my stomach!) I feel like all the docs treat me like a druggie it could be in my head but I do get the feeling even from the pharmacy I feel like a criminal and I’ve never done anything wrong with these stupid meds that do nothing! This Hysingla is sooo expensive! Thanks for letting me rant”

3 / 10
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Works For Me · Taken for 5 to 10 years September 13, 2019

“I have horrible low back and hip problems. I have been taking Hysingla for several years now. It doesn't alleviate all of my pain, but it helps enough that I am able to function. Without Hysingla, it is difficult for me to sit, stand, and walk. I would recommend it to others. Keep in mind that everyone doesn't respond to medicines the same way so they need to work with their doctor to find something that will work.”

9 / 10
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Still hurting · Taken for 1 to 6 months May 1, 2016

“Was forced to switch from 4 to 6 Norco every 24 hrs. to Hysingla ER 30. I've gotten massive headaches every day in the past 6 wks. since starting it, far less pain relief, itching and swollen abdomen. My Dr. insists I need to stick with it.”

1 / 10
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Stormy · Taken for 1 to 6 months August 27, 2018

“I have psoriatic arthritis, osteoarthritis, osteoporosis and fibromyalgia. All of which are very painful. I was on 7.5 narco's. Which actually worked. I have never abused medication. I take them only when needed. My pain WAS controlled. Then my doctor put me on hysingla ER. The medication is worthless. I have NO pain relief at all. When I told the doctor, the nurse red flagged me as an addict.”

1 / 10
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Frequently asked questions

Non addict May 24, 2017

“My Doctor switched me to this, no reason given. I'm 58 I have had Renal Cell Cancer, I have 1 kidney left . Heart Disease, Diabetic, Discs are gone, I am not a surgical candidate due to my health. I have never, taken illegal drugs nor have I failed a random urine test, pill count etc.... But, because of what other people do, I am grouped into that stereotype ... It's embarrassing, humiliating, not everyone is a addict or looking for drugs . But this is the worst drug, I have ever tried...”

1 / 10
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Cronin Pain July 15, 2016

“I've been a chronic pain patient for 10 plus years. My dr wanted me to try Hysingla 100 mg even though my other medication was working the best out of all the others I've tried and been on. I took the first does and I didn't seem to have any relief but I kept reminding myself what he and I discussed so I gave it another try. By this time my other medication is no longer in my system and now my pain is getting really bad so I called my dr's office. I was advised that the Hysingla would peak at 15 hours of taking it and sometimes takes a while to build up. After a few days my dr took me off of it, an asprin worked better then the Hysingla. I hope others don't have to suffer like I did.”

1 / 10
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Dawn 32 · Taken for less than 1 month March 27, 2016

“I find that this medication is unable to relieve my severe back and neck pain. Not only that, I now have severe migraines with use of Hyslinga. I feel that more research was needed before releasing it. I cannot handle increased pain which it had caused asking with dizziness and fatigue.”

4 / 10
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Anahid1 · Taken for less than 1 month June 4, 2016

“This medicine took forever to work at all and didn't touch my foot, back knee, or migraine pain. What it did do is make me horribly nauseous, gave me hot sweats and shakes, made my hair fall out by the handful, and costs almost $200 for 30 pills. The prescription card only covers a month but it was time and money wasted. What a horrible experience!”

1 / 10
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Lumbar/Cspine Fusions Multi Le · Taken for 6 months to 1 year November 20, 2015

“MS-Contin 60mg daily since 1998 w/breakthru pain combo w/MSC-IR 30mg 3x day. Some dizzy + naseau @times w/MSContin. Began Hysingla ER 60mg daily 3 mo ago w/excellent results. No lumbar pain. 80% CSPINE pain reduction + NO side effects period. Does work around clock. Chronic discogenic pain in lumbar since 1989 post 3 level lumbar lami. PCDF C2-C5 + ACDF C5-C6 w/80% pain relief. Miracle Rx for me! NO addic. issues. Feel NO high w/sustained release meds. Just wish price will go down soon! Highly recommend for those w/mod- sev lumbar pain that tolerate opiates well. Also, like MSC, NO liver panels.”

10 / 10
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No more narco · Taken for less than 1 month December 14, 2015

“I took one dose. I had no reduction in pain compared to Norco 10/325, 2-3 a day. In fact, I had more pain. Terrible side effects including a spike in blood pressure, headache, felt woozy, rapid pulse and what I believe to be an anxiety attack. It was a nightmare and all I could do was wait for it to finally ware off. I have impaired kidneys so it took 36 hours to leave my system. Horrible experience!”

1 / 10
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Dee · Taken for 6 months to 1 year March 15, 2019

“I have herniated disks and did the usual, PT, spinal injections, Norco. I also have a liver condition and told doctor I would like to try something easier on the liver so Hysingla saved the day. Works like Norco minus the tylenol. I wouldn't have walked again without it. Not sure about all the negative reviews, I think it works great!”

10 / 10
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SugarLips45 · Taken for less than 1 month March 15, 2015

“Changed from several pills a day to the new Hysingla ER. Was hoping it was something I would like better for just once a day. I do NOT like this medication. You can not control the peaks due to it being time released and its unpredictable. Causes my eyes to feel heavy and hot.You can not drink at all with this drug, it will cause the medication to be released too quickly, possible overdose. I don't like having no control and I was having break though pain as well.”

3 / 10
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Peachie · Taken for less than 1 month June 14, 2018

“I have chronic pain with my lower back, neck and fibromyalgia. Currently took Norco 10/325 every 4 hrs. Dr started me on Hysingla ER 40mg a week ago and I am miserable. Absolutely NO pain control whatsoever! I have called the Doctor three times in the last week, he said to continue taking it as its the same dose I was currently taking. It is NOT working for my pain at all. I take it first thing in the morning and I am allowed one breakthrough Norco. Anyone else have the same issue? I am disgusted with my Pain Management Dr because he is NOT listening! Help”

1 / 10
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spanky 88 June 15, 2015

“After a year of different meds trying to control pain i was put on hysingla er 40 with roxy 15 for breakthru.No medications will t ake all my pain away .Hysingla er 40 with the roxy 15 gives me controlable pain without the high feeling.It has allowed me to be more active.”

9 / 10
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Nikki97 · Taken for 1 to 6 months June 13, 2015

“Hysingla er was a blessing for me!! Dealing with severe chronic pain for 16yrs. When Dr first told me I was very skeptical and at the point I told dr I was ready to have the surgery. I switched my pain medicine from OxyContin ER 20mg 2x day Norco 10mg 2xs day for break thru pain. I was still Watching clock bc I was still in pain waiting for next dose of pain relief. Now I only need 1 hysingla ER 30 mg. amazing!!! The pain does not control me I never thought I would know what it felt like!! If you're curious about HYSINGLA ER ask your Dr. Severely herniations L5/s1 purtrudes 7mm c3/4 purtrudes 4-5mm”

10 / 10
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3level ACDF (2 failed fusions) · Taken for less than 1 month August 29, 2015

“30mg was good, but 40mg took my pain away, it was heaven. Except that 40mg made me so tired and drowsy that all I did was sleep. Couldn't function so that's not acceptable. I would go to bed at 7pm and wake up at 4pm the next day! So I'm going back to 30mg with breakthrough meds. But here is the thing I can't figure out...I take up to 10-15mg hydrocodone for breakthrough pain ON TOP of my Hysingla ER 30 but that doesn't make me sleepy, it actually kind of keeps me up at night. How bizarre is that? It's the same dosage but reacts completely different. That annoys me because the 40 worked perfectly!!! Except for the severe drowsiness. How can Hysingla ER 40mg be so much more sedating than Hysingla ER 30mg w/10-15mg hydrocodone on top???”

7 / 10
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26yrpain · Taken for less than 1 month June 21, 2015

“This has been the most costly, ineffective, pain CAUSING nightmare of my life! Not only did my insurance company deny its use, it actually caused more musculoskeletal then I already have! My joints feel like they have all been run over by a truck! The side effects are horrible! I only just figured out today, after being on this medication for the past 3 weeks, that the actual medication was making my pain worse! I have so much joint pain that I can barely get out of bed, not to mention the constant headache and severe fatigue! I will definitely not continue this medication, in fact, as of today, I am done and am going back to OxyContin. It may have a terrible reputation for being addictive, but at least no side effects!”

1 / 10
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Biteatme1213 · Taken for less than 1 month February 3, 2018

“Before this drug my pain was so extreme that I physically couldn't get out of bed or do any housework. I was miserable to say the least. I went from taking 4 percocet a day (5mg) to taking 20mg hysingla still with 1 or 2 percocet for breakthrough pain. This medication after a couple days has improved my life so much that I am in shock still from the relief. People only see the bad reviews on here and get scared like I did! I had not bad side effects and every time I felt bad pain, shortly later it was relieved. And unlike some other "24 hour" extended release drugs, this one really does last around the clock. Please if you have relief with this medication, share your experience so others can see the good as well when they come to this website!! I hope your experience is as successful as mine has been so far”

10 / 10
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Yogi · Taken for 1 to 2 years June 8, 2019

“I have CRPS (complex regional pain syndrome), which is one of the worst chronic pain conditions known to man, and I get a lot of relief from this medication. Prior to Hysingla I was prescribed Opana ER until it was taken off the market, and I must say I'm thankful for the change. I like the fact that it works without making me feel "drugged." The only downside is constipation that requires daily doses of laxatives. There aren't many extended release choices, but hopefully more options will become available soon for people that aren't getting relief from Hysingla.”

10 / 10
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Anonymous January 16, 2016

“My Dr. just put me on Hysingla ER about a week ago. I take them faithfully every morning at 10a.m. and every morning I wake up with withdrawals. I have to take 2-4 hydro's besides the ER during the day for breakthrough pain, when I wake up in the morning, wow!!! My heart races, my palms are sweaty, extreme anxiety. I've been having to take a regular hydro in the mornings before the Hysingla ER just to tolerate the withdrawals & pain! Maybe being that it has only been going on 1 week since starting that it's wearing off before the 24hrs. not sure, but I know this never happened with Oxycontin. Will have to wait & see, if not better by my next appt. I am definitely changing medications.”

7 / 10
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Lisa4942000 · Taken for 1 to 6 months March 13, 2016

“Was taking 10 7.5/325 daily for severe auto immune joint foot pain and nerve pain. 60mg time release. 9 out of 10 days I'm fully functional like a normal mom. My only issue is IBS... if I take in the AM and have my guts evacuate I am forced to suffer with only my 3 daily allowed break through pain medication. Then if I don't double up the break through the withdrawal symptoms cause my guts to keep dumping. I have slow digestion and it works about 19 to 22 hours. I imagine a regular digestive system would burn through this medicine before 24 hours. I tried it at night first and really enjoyed waking up without pain but had trouble the last 3 hours before the next dose. I would rather spend those wasted hours in bed each morning.”

9 / 10
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yogi the bear · Taken for less than 1 month June 12, 2015

“I'm use to norco 10/325 and I take four a day due to my job and major back problems. I switched to hyslinga er 40 once a day and it hasn't helped at all. I'm still in pain as I lay here and I haven't even noticed anything from the medication it's like tylenol or something. Ur better off with almost anything else good luck to others.”

1 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.