Nucynta ER Interactions
There are 399 drugs known to interact with Nucynta ER (tapentadol), along with 14 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 186 are major, 212 are moderate, and 1 is minor.
- View all 399 medications that may interact with Nucynta ER
- View Nucynta ER alcohol/food interactions (1)
- View Nucynta ER disease interactions (14)
Most frequently checked interactions
View interaction reports for Nucynta ER (tapentadol) and the medicines listed below.
- amitriptyline
- atorvastatin
- baclofen
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- duloxetine
- gabapentin
- hydroxyzine
- levothyroxine
- lisinopril
- losartan
- Lyrica (pregabalin)
- melatonin
- meloxicam
- metformin
- Norco (acetaminophen / hydrocodone)
- omeprazole
- ondansetron
- oxycodone
- pantoprazole
- prednisone
- promethazine
- rosuvastatin
- tizanidine
- topiramate
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Nucynta ER alcohol/food interactions
There is 1 alcohol/food interaction with Nucynta ER (tapentadol).
Nucynta ER disease interactions
There are 14 disease interactions with Nucynta ER (tapentadol) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- biliary tract disease
Report options
More about Nucynta ER (tapentadol)
- Nucynta ER consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (81)
- Drug images
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Oxycodone
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Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Hydroxyzine
Hydroxyzine is an antihistamine used to treat itching, hives, and anxiety. It also acts as a ...
Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
