Skip to Content

Medications for Irritable Bowel Syndrome

Drugs associated with Irritable Bowel Syndrome

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Irritable Bowel Syndrome: A functional bowel disorder characterised by recurrent crampy abdominal pain and diarrhea. Invasive gastrointestinal diagnostics are often unrevealing.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Bentyl Rx B N X 52 reviews
7.0

Generic name: dicyclomine systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
dicyclomine Rx B N X 98 reviews
8.0

Generic name: dicyclomine systemic

Brand name:  Bentyl

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Amitiza Rx C N 38 reviews
7.0

Generic name: lubiprostone systemic

Drug class: chloride channel activators

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
hyoscyamine Rx C N X 50 reviews
8.0

Generic name: hyoscyamine systemic

Brand names:  Levsin, Levsin SL, Levbid, Anaspaz, HyoMax, Hyosyne, Symax Duotab, HyoMax SL, HyoMax SR, Cystospaz, HyoMax FT, NuLev, Symax SR, A-Spaz, Colidrops, Ed-Spaz, HyoMax DT, Hyospaz, IB-Stat, Levsinex, Levsinex SR, Oscimin, Spasdel, Symax FasTab, Symax SL

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Donnatal Rx C N X 17 reviews
9.0

Generic name: atropine / hyoscyamine / phenobarbital / scopolamine systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Librax Rx D 4 X 35 reviews
9.0

Generic name: chlordiazepoxide / clidinium systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Levsin Rx C N X 9 reviews
7.0

Generic name: hyoscyamine systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
chlordiazepoxide / clidinium Rx D 4 X 42 reviews
9.0

Generic name: chlordiazepoxide / clidinium systemic

Brand name:  Librax

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Lotronex Rx B N 17 reviews
9.0

Generic name: alosetron systemic

Drug class: serotoninergic neuroenteric modulators

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
amitriptyline Off Label Rx C N X 49 reviews
8.0

Generic name: amitriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Levsin SL Rx C N X 4 reviews
9.0

Generic name: hyoscyamine systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Levbid Rx C N X Add review
9.0

Generic name: hyoscyamine systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Anaspaz Rx C N X Add review Add

Generic name: hyoscyamine systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Antispasmodic Rx C N X Add review Add

Generic name: atropine / hyoscyamine / phenobarbital / scopolamine systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

 
Linzess Rx C N 104 reviews
7.0

Generic name: linaclotide systemic

Drug class: guanylate cyclase-C agonists

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Cholestyramine Light Off Label Rx C N 1 review
9.0

Generic name: cholestyramine systemic

Drug class: bile acid sequestrants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
atropine / hyoscyamine / phenobarbital / scopolamine Rx C N X 20 reviews
9.0

Generic name: atropine / hyoscyamine / phenobarbital / scopolamine systemic

Brand names:  Donnatal, Antispasmodic, Donnatal Extentabs, Alkabel-SR, B-Donna Tablets, Bellatal, D-Tal, Hyosophen, Me-PB-Hyos, PB-Hyos, Phenohytro, Quadrapax, RE-PB Hyos Elixir, Se-Donna PB HYOS, Servira, Vitetal

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
cholestyramine Off Label Rx C N 31 reviews
9.0

Generic name: cholestyramine systemic

Brand names:  Cholestyramine Light, Questran, Prevalite, Questran Light

Drug class: bile acid sequestrants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Konsyl OTC N N 1 review
10

Generic name: psyllium systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

 
Metamucil OTC N N 4 reviews
6.0

Generic name: psyllium systemic

Drug class: laxatives

For consumers: dosage, interactions, side effects

 
escitalopram Off Label Rx C N X 5 reviews
9.0

Generic name: escitalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
HyoMax Rx C N X 1 review
8.0

Generic name: hyoscyamine systemic

Drug class: anticholinergics/antispasmodics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
nortriptyline Off Label Rx N N X 20 reviews
8.0

Generic name: nortriptyline systemic

Drug class: tricyclic antidepressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Questran Off Label Rx C N 3 reviews
7.0

Generic name: cholestyramine systemic

Drug class: bile acid sequestrants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
venlafaxine Off Label Rx C N X 8 reviews
7.0

Generic name: venlafaxine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
Page 1 2 3 4 Next

Alternative treatments for Irritable Bowel Syndrome

The following products are considered to be alternative treatments or natural remedies for Irritable Bowel Syndrome. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Irritable Bowel Syndrome.

Learn more about Irritable Bowel Syndrome

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

Synonym(s): IBS; Spastic colon

Browse Drugs by Condition

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Hide