Medications for Irritable Bowel Syndrome
Other names: IBS; Spastic colon
Managing Irritable Bowel Syndrome (IBS), also known as spastic colon, involves tailoring treatments to specific symptoms:
- Diarrhea-control: anti-diarrheals, such as loperamide (Imodium A-D), can help control diarrhea. Bile acid binders, such as cholestyramine, colestipol, or colesevelam may also be prescribed
- Constipation predominant: laxatives such as magnesium hydroxide oral or polyethylene glycol can help with constipation. Fiber supplements, such as psyllium can also help
- Antispasmodics, such as dicyclomine can help relieve painful bowel spasms
- Pregabalin or gabapentin may help with bloating and severe pain
- Tricyclic antidepressants, such as imipramine, desipramine, or nortriptyline can help reduce the activity of the nerves that control the intestines and also improve mood if needed
- SSRI antidepressants, such as fluoxetine, paroxetine, can help with constipation and mood
- Newer medications, such as alosetron, eluxadoline, rifaximin, lubiprostone, and linaclotide, can also help relieve symptoms.
Always consult with your doctor to determine the most effective IBS treatment for your specific condition.
Drugs used to treat Irritable Bowel Syndrome
The following list of medications are in some way related to or used in the treatment of this condition.
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Topics under Irritable Bowel Syndrome
Alternative treatments for Irritable Bowel Syndrome
The following products are considered to be alternative treatments or natural remedies for Irritable Bowel Syndrome. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Irritable Bowel Syndrome.
Learn more about Irritable Bowel Syndrome
Symptoms and treatments
Medicine.com guides (external)
|Rating||For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).|
|Activity||Activity is based on recent site visitor activity relative to other medications in the list.|
|Rx/OTC||Prescription or Over-the-counter.|
|Off-label||This medication may not be approved by the FDA for the treatment of this condition.|
|EUA||An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.|
|Expanded Access||Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.|
|A||Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).|
|B||Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.|
|C||Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.|
|D||There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.|
|X||Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.|
|N||FDA has not classified the drug.|
|Controlled Substances Act (CSA) Schedule|
|M||The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.|
|U||CSA Schedule is unknown.|
|N||Is not subject to the Controlled Substances Act.|
|1||Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.|
|2||Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.|
|3||Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.|
|4||Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.|
|5||Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.|
|X||Interacts with Alcohol.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.