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Peripheral opioid receptor mixed agonists/antagonists

What are Peripheral opioid receptor mixed agonists/antagonists?

Opioid receptors are distributed in the central nervous system and the digestive tract. Peripheral acting agonist and antagonist are not able to penetrate the blood brain barrier so only affect the peripheral opioid receptors. Opioid receptors can be divided into four types including mu, delta, kappa and the nociceptin receptors, and these can be further divided into subtypes. Agonist and antagonist that act on these receptors cause a range of effects depending on the subtype of receptor. By selectively combining peripheral agonists and antagonists that act on particular subtypes of opioid receptor, medications can be produced to have a specific effect with reduced unwanted effects.

List of Peripheral opioid receptor mixed agonists/antagonists:

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Viberzi (Pro)
Generic name: eluxadoline
6.7
213 reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See Also

Medical conditions associated with peripheral opioid receptor mixed agonists/antagonists:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.