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Librax

Generic name: chlordiazepoxide and clidinium (klor dye az e POX ide and kli DI nee um)
Brand name: Librax
Drug class: Anticholinergics / antispasmodics

Medically reviewed by Sanjai Sinha, MD. Last updated on Feb 2, 2021.

What is Librax?

Librax is a capsule containing a combination of chlordiazepoxide and clidinium. Chlordiazepoxide is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Clidinium reduces stomach acid and decreases intestinal spasms.

Librax is a prescription medicine that may be effective in treating stomach ulcers, irritable bowel syndrome, or symptoms related to intestinal infection.

Librax is given together with other medications to treat these conditions.

It is not known if Librax is safe and effective in children.

Warnings

Librax can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing.

MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.

You should not use Librax if you have glaucoma, an enlarged prostate, or problems with urination.

Do not use Librax if you are allergic to chlordiazepoxide or clidinium, or to other benzodiazepines, such as alprazolam (Xanax), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax). Chlordiazepoxide and clidinium can cause birth defects in an unborn baby. Do not use this medicine if you are pregnant.

Do not drink alcohol while taking Librax. This medication can increase the effects of alcohol. Librax can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. This medication may be habit-forming and should be used only by the person it was prescribed for.

Before taking this medicine

You should not use Librax if you are allergic to chlordiazepoxide or clidinium, or if you have:

  • glaucoma; or

  • an enlarged prostate and problems with urination.

To make sure Librax is safe for you, tell your doctor if you have ever had:

  • eye problems;

  • urination problems;

  • problems with coordination;

  • bleeding problems;

  • liver or kidney disease;

  • depression, mental illness, or suicidal thoughts or behavior;

  • drug or alcohol addiction; or

  • if you use a narcotic (opioid) medication.

Tell your doctor if you are pregnant or plan to become pregnant. Chlordiazepoxide and clidinium may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Librax while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

It may not be safe to breastfeed while using this medicine. Clidinium can slow breast milk production. Ask your doctor about any risk.

Librax is not approved for use by anyone younger than 18 years old.

How should I take Librax?

Take Librax exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.

Librax is usually taken before meals and at bedtime. Follow your doctor's instructions.

Call your doctor if your symptoms do not improve, or if they get worse.

Do not stop using this medicine suddenly, or you could have unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Dosing information

Usual Adult Dose for Peptic Ulcer:

Chlordiazepoxide 5 mg-clidinium 2.5 mg capsules:
-Maintenance dose: 1 to 2 capsules orally 3 to 4 times a day.

Usual Adult Dose for Irritable Bowel Syndrome:

Chlordiazepoxide 5 mg-clidinium 2.5 mg capsules:
-Maintenance dose: 1 to 2 capsules orally 3 to 4 times a day.

Usual Adult Dose for Enterocolitis:

Chlordiazepoxide 5 mg-clidinium 2.5 mg capsules:
-Maintenance dose: 1 to 2 capsules orally 3 to 4 times a day.

Usual Geriatric Dose for Peptic Ulcer:

Chlordiazepoxide 5 mg-clidinium 2.5 mg capsules:
-Initial dose: 1 capsule orally 2 times a day, increasing the dose gradually as needed and tolerated.

Usual Geriatric Dose for Irritable Bowel Syndrome:

Chlordiazepoxide 5 mg-clidinium 2.5 mg capsules:
-Initial dose: 1 capsule orally 2 times a day, increasing the dose gradually as needed and tolerated.

Usual Geriatric Dose for Enterocolitis:

Chlordiazepoxide 5 mg-clidinium 2.5 mg capsules:
-Initial dose: 1 capsule orally 2 times a day, increasing the dose gradually as needed and tolerated.

Comments:
-The dosage should be individualized to the lowest effective dose, and should be determined by the diagnosis and the patient's response.
-Doses should be administered before meals and at bedtime.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, confusion, muscle weakness, or coma.

What to avoid

Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Librax side effects

Get emergency medical help if you have signs of an allergic reaction to Librax: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. A person caring for you should seek emergency medical attention if you have weak or shallow breathing, if you are hard to wake up, or if you stop breathing.

Call your doctor at once if you have:

  • severe drowsiness;

  • a light-headed feeling, like you might pass out;

  • problems with balance or coordination;

  • confusion, excitement, anger, or feeling restless;

  • severe constipation;

  • painful or difficult urination;

  • restless muscle movements in your eyes, tongue, jaw, or neck;

  • fever, chills, sore throat; or

  • jaundice (yellowing of the skin or eyes).

The sedative effects of this medicine may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury.

Common Librax side effects may include:

  • dry mouth;

  • blurred vision;

  • constipation, nausea;

  • urination problems;

  • drowsiness, dizziness;

  • rash;

  • swelling;

  • irregular menstrual periods; or

  • increased or decreased interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Librax?

Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, prescription cough medicine, or medicine for depression or seizures.

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may interact with chlordiazepoxide and clidinium, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

  • Your pharmacist has information about Librax.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Librax only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.