Librax Side Effects

Generic Name: chlordiazepoxide / clidinium

Note: This document contains side effect information about chlordiazepoxide / clidinium. Some of the dosage forms listed on this page may not apply to the brand name Librax.

For the Consumer

Applies to chlordiazepoxide / clidinium: oral capsule

Along with its needed effects, chlordiazepoxide / clidinium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking chlordiazepoxide / clidinium:

• Abdominal or stomach pain
• chills
• clay-colored stools
• confusion
• cough or hoarseness
• dark urine
• difficulty with speaking
• dizziness
• drooling
• drowsiness
• fever with or without chills
• general feeling of tiredness or weakness
• headache
• itching or rash
• loss of appetite
• loss of balance control
• lower back or side pain
• muscle trembling, jerking, or stiffness
• nausea
• painful or difficult urination
• pale skin
• restlessness
• shakiness and unsteady walk
• shuffling walk
• sore throat
• sores, ulcers, or white spots on the lips or in the mouth
• stiffness of the limbs
• swelling
• twisting movements of the body
• uncontrolled movements, especially of the face, neck, and back
• unpleasant breath odor
• unsteadiness, trembling, or other problems with muscle control or coordination
• unusual bruising or bleeding
• unusual tiredness or weakness
• vomiting of blood
• yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking chlordiazepoxide / clidinium:

• Blurred vision
• change in consciousness
• difficulty having a bowel movement (stool)
• dry mouth
• lack of coordination
• loss of consciousness
• sleepiness or unusual drowsiness

Some side effects of chlordiazepoxide / clidinium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Inability to have or keep an erection
• increase or loss in sexual ability, desire, drive, or performance
• increased or decreased interest in sexual intercourse
• menstrual changes
• skin blisters

For Healthcare Professionals

Applies to chlordiazepoxide / clidinium: oral capsule

Nervous system

The elderly and debilitated may be more susceptible to the side effects of chlordiazepoxide-clidinium. Drowsiness, ataxia, and confusion have occasionally been reported at the lower dosage ranges.^[Ref]

Nervous system side effects have included drowsiness, ataxia, confusion, and extrapyramidal symptoms. Chlordiazepoxide-clidinium may impair the psychomotor skills necessary for driving. Changes in electroencephalogram (EEG) patterns (low-voltage fast activity) have been reported during and after chlordiazepoxide treatment.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea, constipation, and dryness of the mouth.^[Ref]

Hematologic

Hematologic side effects have included blood dyscrasias (including agranulocytosis).^[Ref]

Hepatic

Hepatic side effects have included jaundice and hepatic dysfunction.^[Ref]

Other

Other side effects have included increased and decreased libido, edema, and withdrawal symptoms. Rarely, syncope has been reported.^[Ref]

Withdrawal symptoms after abrupt cessation of chlordiazepoxide-clidinium may include dysphoria, insomnia, convulsions, tremor, abdominal and muscle cramps, vomiting, sweating, agitation, restlessness, and anxiety.^[Ref]

Ocular

Ocular side effects have included blurring of vision.^[Ref]

Genitourinary

Genitourinary side effects have included minor menstrual irregularities and urinary hesitancy.^[Ref]

Dermatologic

Dermatologic side effects have included skin eruptions.^[Ref]

Some side effects of Librax may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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