Librax Side Effects

Generic name: chlordiazepoxide / clidinium

Medically reviewed by Drugs.com. Last updated on Apr 12, 2025.

Note: This document provides detailed information about Librax Side Effects associated with chlordiazepoxide / clidinium. Some dosage forms listed on this page may not apply specifically to the brand name Librax.

Applies to chlordiazepoxide / clidinium: oral capsule.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Tell your doctor if you are pregnant or planning to become pregnant. Using this medicine during the later pregnancy may cause problems in your newborn baby (eg, sedation or withdrawal symptoms). Tell your doctor right away if your baby has an abnormal sleep pattern, diarrhea, feeding problems, a high-pitched cry, irritability, low muscle tone, restlessness, shakiness or tremors, sluggishness, trouble breathing, weight loss, vomiting, or fails to gain weight. If you think you have become pregnant while using the medicine, tell your doctor right away.

This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

This medicine may cause some people, especially elderly patients, to become drowsy, dizzy, lightheaded, clumsy or unsteady, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to think or see well.

Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). The use of alcohol or other medicines that affect the CNS with Librax® may worsen the side effects of this medicine, such as dizziness, irregular, fast or slow, or shallow breathing, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics.

If you develop any unusual and strange thoughts or behavior while you are taking chlordiazepoxide, be sure to discuss it with your doctor. Some changes that have occurred in people taking this medicine are like those seen in people who drink alcohol and then act in a manner that is not normal. Other changes may be more unusual and extreme, such as confusion, worsening of depression, suicidal thoughts, and unusual excitement, nervousness, or irritability.

Do not suddenly Stop taking chlordiazepoxide / clidinium without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent a worsening of your condition and reduce the possibility of withdrawal symptoms, including headache, nausea, general feeling of discomfort or illness, seizures, stomach or muscle cramps, tremors, or unusual behavior.

Symptoms of an overdose include: blurred vision, change in consciousness, changes in patterns and rhythms of speech, confusion, difficult urination, difficulty having a bowel movement, dry mouth, hallucinations, lack of coordination, loss of consciousness, loss of strength or energy, muscle pain or weakness, nightmares, sleepiness or unusual drowsiness, shakiness and unsteady walk, slurred speech, trouble in speaking, trouble sleeping, unsteadiness, trembling, or other problems with muscle control or coordination, unusual drowsiness, dullness, tiredness, weakness or feeling of sluggishness, unusual excitement, nervousness, restlessness, or irritability, unusual weak feeling. Call your doctor right away if you notice these symptoms.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Librax

Along with its needed effects, chlordiazepoxide / clidinium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking chlordiazepoxide / clidinium:

Get emergency help immediately if any of the following symptoms of overdose occur while taking chlordiazepoxide / clidinium:

Symptoms of overdose

• agitation
• blurred vision
• change in consciousness
• changes in patterns and rhythms of speech
• confusion
• difficulty having a bowel movement (stool)
• dry mouth
• lack of coordination
• loss of consciousness
• loss of strength or energy
• nightmares
• shakiness and unsteady walk
• sleepiness or unusual drowsiness
• slurred speech
• talkativeness
• trouble speaking
• unsteadiness, trembling, or other problems with muscle control or coordination
• unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
• unusual excitement, nervousness, restlessness, or irritability
• unusual paleness

Other side effects of Librax

Some side effects of chlordiazepoxide / clidinium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to chlordiazepoxide / clidinium: oral capsule.

General adverse events

The most commonly reported side effects included anticholinergic effects (e.g., blurred vision, constipation, dry mouth, urinary hesitancy).^[Ref]

Psychiatric

• Uncommon (0.1% to 1%): Decreased libido, increased libido
• Rare (0.01% to 0.1%): Confusion^[Ref]

The elderly and debilitated may be more susceptible to confusion; this side effect has occasionally been reported at the lower dosage ranges.^[Ref]

Gastrointestinal

• Uncommon (0.1% to 1%): Constipation, nausea
• Frequency not reported: Dry mouth^[Ref]

Constipation most commonly occurred when patients took spasmolytic agents concurrently and/or with a low residue diet.^[Ref]

Hepatic

• Uncommon (0.1% to 1%): Jaundice, liver dysfunction^[Ref]

Hematologic

• Uncommon (0.1% to 1%): Agranulocytosis, blood dyscrasias^[Ref]

Nervous system

• Uncommon (0.1% to 1%): Extrapyramidal symptoms
• Rare (0.01% to 0.1%): Drowsiness
• Very rare (less than 0.01%): Syncope
• Frequency not reported: Anticholinergic effects, changes in EEG patterns (low-voltage fast activity)^[Ref]

The elderly and debilitated may be more susceptible to drowsiness and syncope; the side effects have occasionally been reported at the lower dosage ranges.^[Ref]

Genitourinary

• Uncommon (0.1% to 1%): Minor menstrual irregularities
• Frequency not reported: Urinary hesitancy^[Ref]

Cardiovascular

• Uncommon (0.1% to 1%): Edema^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Skin eruptions^[Ref]

Other

• Rare (0.01% to 0.1%): Ataxia^[Ref]

The elderly and debilitated may be more susceptible to ataxia; this side effect has occasionally been reported at the lower dosage ranges.^[Ref]

Ocular

• Frequency not reported: Blurred vision^[Ref]

See also:

Further information

Librax side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer