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Serotoninergic neuroenteric modulators

What are Serotoninergic neuroenteric modulators?

Serotoninergic neuroenteric modulators bind to the serotonin receptors in the gastrointestinal tract and either act as an agonist or antagonist.

One of the agents in this class is a selective serotonin receptor antagonist, so it binds to the serotonin receptor and blocks the action of serotonin in the gastrointestinal tract. The agent with serotonin receptor antagonist activity is used to relieve cramping, abdominal discomfort, diarrhea, etc. associated with irritable bowel syndrome.

The other agents in this category are selective serotonin receptor agonists that act in the gastrointestinal tract to regulate bowel function. It is used to treat chronic constipation and constipation related to irritable bowel syndrome.

List of Serotoninergic neuroenteric modulators:

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Drug Name Reviews Avg. Ratings
Zelnorm (Pro)
Generic name: tegaserod
32 reviews
Lotronex (Pro)
Generic name: alosetron
21 reviews
Motegrity (Pro)
Generic name: prucalopride
2 reviews

Further information

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See Also

Medical conditions associated with serotoninergic neuroenteric modulators: