Linzess Interactions
There are 59 drugs known to interact with Linzess (linaclotide), along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 10 are moderate, and 49 are minor.
- View all 59 medications that may interact with Linzess
- View Linzess alcohol/food interactions (1)
- View Linzess disease interactions (2)
Most frequently checked interactions
View interaction reports for Linzess (linaclotide) and the medicines listed below.
- albuterol
- amlodipine
- aspirin
- atorvastatin
- baclofen
- bupropion
- cyclobenzaprine
- Cymbalta (duloxetine)
- duloxetine
- famotidine
- gabapentin
- hydroxyzine
- levothyroxine
- lisinopril
- losartan
- Lyrica (pregabalin)
- melatonin
- meloxicam
- metformin
- MiraLAX (polyethylene glycol 3350)
- montelukast
- omeprazole
- ondansetron
- pantoprazole
- prednisone
- tizanidine
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Linzess alcohol/food interactions
There is 1 alcohol/food interaction with Linzess (linaclotide).
Linzess disease interactions
There are 2 disease interactions with Linzess (linaclotide) which include:
More about Linzess (linaclotide)
- Linzess consumer information
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- Reviews (885)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Support group
- FDA approval history
- Drug class: guanylate cyclase-C agonists
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
MiraLAX
MiraLAX (polyethylene glycol) is used as a laxative to treat occasional constipation or irregular ...
Bentyl
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Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Xifaxan
Xifaxan (rifaximin) is used to treat travelers' diarrhea, irritable bowel syndrome with diarrhea ...
Metamucil
Metamucil is used for constipation, dietary fiber supplementation, irritable bowel syndrome
Amitiza
Amitiza (lubiprostone) is used to treat chronic constipation and irritable bowel syndrome with ...
Psyllium
Psyllium systemic is used for constipation, diarrhea, chronic, dietary fiber supplementation ...
Lubiprostone
Lubiprostone systemic is used for chronic idiopathic constipation, constipation, irritable bowel ...
Polyethylene glycol 3350
Polyethylene glycol 3350 systemic is used for bowel preparation, constipation, constipation, acute ...
Hyoscyamine
Hyoscyamine systemic is used for anesthesia, anticholinesterase poisoning, crohn's disease ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.