Linzess Alternatives Compared
| Linzess Remove Linzess from your drug comparison | Lactulose Remove Lactulose from your drug comparison | Amitiza Remove Amitiza from your drug comparison |
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| Linzess linaclotide Remove Linzess from your drug comparison | Lactulose Remove Lactulose from your drug comparison | Amitiza lubiprostone Remove Amitiza from your drug comparison |
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Prescribed for Constipation - Chronic, Irritable Bowel Syndrome, Constipation. Linzess may also be used for purposes not listed in this medication guide. |
Prescribed for Hepatic Encephalopathy, Constipation - Chronic, Constipation - Acute. lactulose may also be used for purposes not listed in this medication guide. |
Prescribed for Constipation - Chronic, Opioid-Induced Constipation, Irritable Bowel Syndrome, Constipation - Drug Induced, Constipation. Amitiza may also be used for purposes not listed in this... View more |
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Prescription only |
Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Common side effects include: diarrhea. See the full Linzess side effects document. |
See the full lactulose side effects document. |
Common side effects include: diarrhea, headache, nausea. See the full Amitiza side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Linzess prices |
View all lactulose prices |
View all Amitiza prices and generic prices |
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Generic Availability |
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No |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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N/A |
Cholac, Constilac, Enulose, Generlac, Kristalose |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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N/A |
N/A |
N/A |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 58 drugs are known to interact with Linzess:
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A total of 235 drugs are known to interact with lactulose:
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A total of 1 drugs are known to interact with Amitiza:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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August 30, 2012 |
N/A |
January 31, 2006 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.