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User Reviews for Linzess

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Constipation 52 reviews 244 medications
   
7.5
Irritable Bowel Syndrome 118 reviews 139 medications
   
7.3
Constipation, Chronic 231 reviews 30 medications
   
7.3
Summary of Linzess reviews 401 reviews 7.4

Reviews for Linzess

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For Constipation "I have found perfect combo for me. I take one Linzess (145 MCG) at least one hour before breakfast and a tbs of Citracel orange drink every morning. Linzess alone lost its effectiveness within a few weeks. I am 5' tall 110 lbs 75 years young. This combo keeps me as regular as clockwork for now."

   
9.0

Miss med April 21, 2017

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For Irritable Bowel Syndrome "I was diagnosed with IBS-C about a year and a half ago. No laxatives were working at all. I was first prescribed with linzess 145, that did nothing for me. Then my doc upped the dosage to 290. That helped a little more. Then he added Amatiza. I now have to take 2 Amatiza and a 290 for anything to happen for me. The bloating is insane and the water retention is unreal. Living my life constantly sick is no fun!"

   
5.0

JDailey April 16, 2017

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For Constipation, Chronic "I have been on this for about a week. After 20 years of complete idiopathic chronic constipation I had to take Mag Cit-rate or MOM every three days and wear a depends. It was necessary to stay alive and as I said 20 years (3 trips to Mayo Clinic and no help). I've not had any side effects that I am aware of yet. First morning I took it and had a bowel movement the next morning and it was a substantial and well formed movement. Later that night before bed, I had an urge and had another significant bowel movement. Second day same situation and had good bowel movement when I got up (within 2 hours). If this stays effective and no side effects emerge, my life has changed wonderfully forever. I could not travel before and had to wear a depends after magnesium as I never knew when I would get hit for about 16 hours. I have had no diarrhea with Linzess or bloating or pain. I hope prices go down or a generic occurs as I paid about $350.00 for 30 290mg capsules. Also, I pray that nothing occurs where this shows over time to have any negative side effects. I took Amitiza over 10 years ago and had agony and very poor results. I lost faith in all new drugs as they all panned out to have some serious problems so I waited on Linzess for over 5 years before trying it. No horror stories emerged and now, unless it stops working, I'm truly amazed after 20 + years of constant constipation. I didn't have over two or three Bm'S in 20 years without a magnesium product and they were getting more frequent for use with age. I'm happy to write this because I had given up and had considered having a colostomy or colectomy if I was a candidate. 10 stars for Linzess!"

   
10

Hornbeak (taken for 1 to 6 months) March 31, 2017

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For Constipation, Chronic "Linzess 145mcg gave me explosive diarrhea for hours. I thought I must have eaten something bad so I waited a day and took Linzess again and about 2 1/2 hours later it happened again and lasted 5 hours. Obviously not for me. I strongly suggest you're at home the first time you take this just in case."

   
1.0

goldengurl (taken for less than 1 month) March 29, 2017

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For Constipation, Chronic "I am 68 years old and a recently retired registered nurse. I have had problems off and on with irregularity most of my adult life. I used OTC laxatives sporadically and ate a lot of roughage. 6 months ago, I had a minimally invasive mitral valve repair, followed by a heart attack and stroke 6 days post-op, and an emergency cardiac stent. I had been prescribed Ativan for anxiety and Tramadol for pain as well as Amiodarone. All of these contributed to chronic constipation. A few months back, I thought I was having a bowel obstruction. My primary physician recently prescribed Linzess. Within hours, I experienced a bowel movement without STRAINING for the 1st time in 6 months. It was the best day I've had since last August."

   
10

Gratefuljcc March 29, 2017

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For Constipation, Chronic "With being on this medicine in a day and a half I am experiencing chronic diarrhea it is horrible I will not take this medicine no more I did not know no side effects until I Googled for side effects."

   
1.0

Dustyroe March 27, 2017

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For Constipation, Chronic "I took the 145 mcg for chronic constipation. It worked ok for a week then I didn't have a bowel movement for a couple of days, then diarrhea one day and regular movement the next. I got a lot of gas and flatulence. Within a month it stopped working so I contacted my doctor. He said to take 2 capsules equal to 290 mcgs. I got diarrhea for 2 days, then no bowel movement then some normal movement. More gas pains and flatulence. Very disappointed with the medication. Doesn't really work as advertised. I will tell my doctor about it when I see him for my follow up. This medication sucks."

   
2.0

BamBamFrogette (taken for 1 to 6 months) March 25, 2017

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For Constipation "Taking this now for 5 weeks and I feel good but I have severe diarrhea so I have stopped and have an appt next week with my Dr."

   
10

Pfromyourbuttlol (taken for 1 to 6 months) March 24, 2017

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For Constipation, Chronic "This medication has been a great for me. I take it every morning (the lowest dose) on an empty stomach when I first wake up. I have had many years of chronic constipation and have tried MANY different things. This is the only thing that has really worked for me. Fortunately, I have not had the diarrhea issues that some people have reported. My doctor did say this can be a side effect for some. For others like me, it has worked great. Like any medication, there is always the chance you may have side effects and have to discontinue it. I think it's worth trying to see if it's right for you if you have had years of constipation that has effected your quality of life."

   
10

Sunny246 March 23, 2017

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For Irritable Bowel Syndrome "How come the makers of this drug don't mention the weight gain associated with taking it? It works well for about a week and then the bloating and weight gain sets in. More than very disappointing and shame on them!"

   
1.0

majjalam March 23, 2017

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For Irritable Bowel Syndrome "I can't believe my insurance agreed to cover this! It's $10 per pill otherwise. The 145mcg is a high enough dosage. 290mcg and your system will go nuts. This medicine works great and usually within 12 hours. Take it at the night, not in the morning like the instructions say. Make sure you have the day off. Best way to take it, have a light dinner, wait one hour, have dessert. In one hour you will have bloating, cramps and gas. The cramps and bloating are normal. It means your system is moving. By the next morning (maybe sooner) the bowel movements will start. DO NOT TAKE THIS EVERYDAY! Your body will build an immunity if you do. Keep hydrated as you will lose quite a bit of water."

   
10

Johnnylakis (taken for less than 1 month) March 18, 2017

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For Constipation, Chronic "I can truly say this medication has changed my life! I have had years of constipation and used suppositories and Mirilax on a regular basis. Other oral medications were too harsh and cause me to throw up. I tried Linzess a year go and I didn't give myself enough time to adjust to the medication, lots of diarrhea. But my doctor encouraged me to try again and commit to it for a few weeks. Sure enough the side effects tapers off and things are mostly regular . It is very expensive and my doctor had to go through hoops to get the medication approved by my insurance."

   
9.0

Craziercatlady March 17, 2017

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For Irritable Bowel Syndrome "I started taking Linzess 3 weeks ago for IBS-C. I have suffered with IBS since I was 18 or so. If I didn't take anything over the counter I could go 4-5 days without a movement. My Dr gave me the starting dose which had little effect for me. Once he called in the 290 mg I can't believe the difference. Sure I've had a couple of headaches and bloating, but it has been a God send to me. No diarrhea for me at all. I am going everyday, sometimes more than once a day and have actually lost 5 lbs. I am also surprised see when people say they've experienced rapid weight gain because I've experienced the exact opposite. Glad I didn't read those reviews before starting!"

   
8.0

Kris3592 March 15, 2017

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For Irritable Bowel Syndrome "I have been taking Linzess 290 mg for over 3 months now. In the beginning I had a few experiences of diarrhea but not so much now. What I cannot take is the stomach pain, gas and bloating which has gotten worse over time. I stopped taking the drug for a few days to determine if these symptoms were from the drug and they were. The stomach paid came right back today when I took a dose. While it does help with the constipation it is not worth the other side effects. Back to magnesium capsules I go."

   
5.0

faerychica March 9, 2017

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For Constipation, Chronic "I've been using linzess 290 for a couple of years off and on because if stops working after a couple of months. I started it again and I'm finishing up my 2nd bottle and nothing. No results whatsoever. I use enemas a couple times a week and all I can get out are hard, round, tiny, rock like poop is all I get. I don't know what else to do."

   
1.0

KLVD March 9, 2017

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For Constipation, Chronic "I suffer with cc frequently. Until Linzes the only relief was magnesium citrate. I use it more on a as needed basis as it frequently brings on a watery stool for a few hours after taking for a couple days. It has brought my cc into a manageable situation. There can be slight lower back discomfort when the watery stool occurs but it prevents all the abdominal pain associated with my cc."

   
9.0

Crifdog March 4, 2017

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For Irritable Bowel Syndrome "Linzess has been extremely helpful for my constipation. I am able to go every day now, sometimes more then once. My only two complaints are the diarrhea and weight gain. I am a bit of a gym addict and go at least 5 times per week, running and weight lifting. I have a very healthy diet around 1300 calories a day, high protein and fiber, low fat, low carb and low sugar. Since I have been on Linzess (4 weeks consistantly), I have gained 7lbs. I believe I am retaining water despite being able to go to the bathroom often. This is the only drug that has worked to alleviate the constipation and I have tried MANY! However, I am not happy about the bloating and weight gain."

   
7.0

Anonymous (taken for 1 to 6 months) March 1, 2017

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For Constipation, Chronic "Took Linzess for one month. Side effect is diarrhea so I stayed close to bathroom. Diarrhea tapered off. On day 31 diarrhea hit hard all day. I don't like the severe diarrhea. I skipped one dose and bowel movement was normal."

   
10

Catt73338888 (taken for 1 to 6 months) February 24, 2017

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For Constipation, Chronic "I have suffered from constipation for years. Only going about once a month, usually brought on by menstrual cramps. I've been in and out of the ER having them clean me out. Nothing seemed to work. And this works way too well. I take one pill and about 3 hours later I have ungodly diarrhea for the next few hours. I'm not complaining it takes away the pain and the bloating and the miserable from the constipation. But I have no idea how people would take one capsule every day. Once I've taken a capsule and have the diarrhea for a few hours I seem to not have any trouble for a few months. The doctor had originally give me samples enough for 30 day supply. But I've only had to use 5 in the last year."

SLO going (taken for 6 months to 1 year) February 9, 2017

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For Constipation, Chronic "I have had positive experience with Miralax, but I'm not supposed to use that long term. I tried Linzess for 2 weeks. I wound up with constipation, hemorrhoids, blood, and pain. Not fun! I'm back with what works for me. Linzess was a waste of my time. I'm now gun shy to try anything else."

   
1.0

Psycho 1 (taken for less than 1 month) February 4, 2017

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For Irritable Bowel Syndrome "It worked from the first day but I also had at least one episode a day of severe D I used it for 22 days and then called the manufacurer for some input The said D was the usual complaint when there was a complaint and they had no recommendations except to speak to my doctor I decided to try it every other day and have done that only for the last 4 days There is a slight improvement. Very slight in the D attacks I will do this for the next 3 weeks (using it every other day ) and then see what point I am at. I no longer get these terrible painful IBS C attacks where I thought I was going to die from the pain. No more blood in the John. The doctor told me to take the Lizness with Colace and Senna but I was afraid to do that."

   
8.0

abeynorm February 4, 2017

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For Constipation "Chronic constipation has been a problem most of my life. I was on Zelnorm, until it was take of the market by the FDA. I have had serious complications due to my constipation, including having to be surgically unimpacted last yr after neck surgery. Almost was the end for me, I was septic. Full recovery, and put on Linzess 5 months ago, and it's been a miracle for me. Yes, I do get some gas, and can't leave home right away, it's sudden and quick when it works. I've gotten use to the small side effects now. I go everyday, and I have had NO more issues with constipation. I love Linzess!"

   
10

Bethhg22 January 29, 2017

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For Constipation, Chronic "Has been a wonder drug for me! Have suffered from extreme constipation for years. Now have a regular bowel movement about 2 hrs after I take it. Took about 2 weeks to work so give it some time! Have never had the diarrhea side effect."

   
10

Karenburkeh (taken for 1 to 6 months) January 28, 2017

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For Constipation, Chronic "It does not work for me. Has anyone else ever realized that capsule is empty or is it just my bottles I open the capsule up I am on one45 MCG one to two times daily I quit taking it because it was not working I started back on it 6 days ago then today open the capsule and realized there is nothing in it!"

   
1.0

arnau January 22, 2017

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For Constipation, Chronic "I got these as samples from my doctor for constipation, these pills worsened my anxiety. I started feeling very nervous and shaking, after two days of taking these I realized it was these pills that triggered my anxiety. Plus I didn't noticed them help with my constipation. Maybe if I would have taken them longer they would have helped."

   
2.0

Unknown95 January 22, 2017

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