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User Reviews for Linzess

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Constipation 52 reviews 247 medications
   
7.3
Constipation, Chronic 244 reviews 30 medications
   
7.3
Irritable Bowel Syndrome 125 reviews 141 medications
   
7.2
Summary of Linzess reviews 421 reviews 7.3

Reviews for Linzess

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For Constipation, Chronic "I have been on this medication for a while now. Without it I cannot go to the bathroom but with it I get diarrhea. It seems to mess with the consistency of my stool. It's good to feel cleaned out but it interrupts one's day and made me feel like I always had to be near a bathroom. It works (typically) within 2-3 hours. I wish that the 72 was a low enough dosage but it's not and amitiza is ironically also too strong yet no OTC remedies work well enough for me. Hopeful another solution will come with time"

   
6.0

Annoyedbyconstipation June 23, 2017

1 users found this comment helpful.

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For Constipation, Chronic "I spoke with my doctor about constipation I am having on this diet. He walked me in the supply closet and handed me a sample of Linzess. I go to my desk and sit and start working away, about 30 minutes later my life would be forever changed. This medicine was made in the deepest, fiery depths of hell, this was a nuclear bomb I just swallowed. I am sure of it. As I am sitting at my desk and feel my stomach wrenching and bending as if someone was hand washing my colon, every inch of it, then the sweat, as if I had just ran a half mile marathon in record time. I am sitting at my desk still thinking it could not be this medicine I literally just took it 34 minutes ago I kept thinking. How can one pill in 34 minutes solve a lifelong problem? I will tell you how because satan himself is in this capsule. I immediately run to the bathroom because once again someone is hand washing every inch of my intestine..Oh Lord make the pain go away, and then he answered...The gates to hell opened up and it all began, I sat in a bathroom all day in periodic episodes for a total of 23 times. Please friends beware, I have warned you don't trust a medicine that can cure a lifelong problem in 30 minutes. I even heard my physician do a evil giggle as I scurried into the bathroom. I truly believe it was payback for my extended lunches."

   
10

Handwashed (taken for less than 1 month) June 22, 2017

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For Constipation, Chronic "I am a 21 year old female who suffers with IBS-C. Before this medication I would only go to the bathroom about once a week or sometimes go two weeks. I have been in Linzess 145mg for a week now and it has changed my life forever! My doctor prescribed me to take it in the morning with 2 fiber gummies 30min before breakfast. I now go to the bathroom twice a day! My cramps are not bad and go away once I use the bathroom. I don't get any dizziness. I almost did not take this medication because of the negative reviews but I'm glad I looked passed it! Ask you doctor for coupons as well, I got a coupon for a 90 day supply for $30. Good luck!"

   
10

T.B (taken for less than 1 month) June 20, 2017

7 users found this comment helpful.

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For Constipation, Chronic "I am on day two of Linzess 145 mcg. for chronic constipation. Taking one in the morning on an empty stomach with 16 oz of water, then eating half hour later, oatmeal or toast. I am pleased with the results, and have not had any of the negative things other reviewers have mentioned. Sadly, I almost let the negative reviews keep me from even trying this medication, so glad I decided to see for myself and tried it. I already feel better after day two and am looking forward to tomorrow so I can take it again! Of course you will have diarrhea, at least until your body adjusts. But so what? It's much better than constipation! One negative though is how costly this drug is if you do not have an insurance prescription program. If you are thinking about trying Linzess, please don't be discouraged by the negative reviews, at least give it a try and see how it works for you. Again, I'm only on day two, but I'm pretty sure this drug and I are going to be best friends forever!"

Cat3 (taken for less than 1 month) June 17, 2017

9 users found this comment helpful.

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For Constipation, Chronic "So I took one yesterday and nothing happened. Took one today around 4ish. Around 6pm I started to have severe gas and bloating. My stomach has been bubbling since 6pm it is now 1am and I have been having explosive diarrhea since 7pm. Just want to go to sleep on the toilet. My butt is raw now and my stomach is bubbling now as I type. I counted seven trips to the bathroom. Good luck to anyone who takes this."

S.j (taken for less than 1 month) June 14, 2017

10 users found this comment helpful.

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For Irritable Bowel Syndrome "I have suffered from IBS Constipation/Diarrhea for as long as I can remember. I took this medicine for a year and a half along with Dycyclomine. It seemed to work for a couple months but then the symptoms came back. I consider myself a very active woman, working out at least 5 days a week, yoga, clean eating... I noticed as soon as I started taking the medicine I gained 10 pounds, lost all of energy and had severe muscle and joint aching. I continued the medicine and went back to the doctor with questions. Recently I had an episode and I received a full abdominal ultrasound. Everything normal but full of gas that would not move. I decided to stop the meds and a week later all the side effects are gone."

   
4.0

Audz40 (taken for 1 to 2 years) June 13, 2017

3 users found this comment helpful.

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For Constipation, Chronic "I have IBS, hiatal hernia and diverticulosis. Sometimes linzess does not work I have to take stool softners everyday to have relief."

   
6.0

Gizmo415 (taken for 2 to 5 years) June 11, 2017

5 users found this comment helpful.

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For Constipation, Chronic "I have suffered from chronic constipation for well over 10 years, I have just started using linzess for 2 weeks and I had my first bowel movement without an enema or without milk of magnesia or Senna the second day of using it , (in 10) years even though most of it has been diarrhea, I would rather have diarrhea then to not use the bathroom for up to 10 days get deathly ill and have to go to the ER. Linzess so far has been wonderful, I feel much better. The nausea and stomach pain has reduced dramatically! I am thinking if I take linzess every other day instead of every day it will not be diarrhea but will be a regular stool so we will see how that goes. Two thumbs up to this medication."

   
9.0

Meesh meesh June 11, 2017

10 users found this comment helpful.

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For Constipation, Chronic "I have been taking linzess for three weeks. I have to get off it..I have been having terrible head pain. Feels more like I'm having vessel problems. I'm not going to risk having an aneurysm for a pill. I was scared this morning as the pain was almost unbearable."

   
3.0

sherkh June 9, 2017

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For Constipation, Chronic "This drug caused me pain and blood in stool. It provided no benefit for me. I will never take this drug again."

   
1.0

jamie1000 June 9, 2017

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For Irritable Bowel Syndrome "I started taking Linzess 145 in January 2017. It worked great for a couple of weeks and the suddenly stopped working. I had to resort to Milk of Mag. I gave it another try and it worked on and off. I gave it one more try and all I have is horrible gas and cramps even after bowel movement. Seems like my life revolved around this med. I have appointment with my PCP next week and will discuss with her. I am currently not taking any medication but still feel effects from it after 5 days of not taking it."

   
2.0

Disapointed (taken for 1 to 6 months) June 8, 2017

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For Irritable Bowel Syndrome "It takes a while to adjust to this medication and find the proper dose. Also, and this is not commonly publicized, this drug is extremely sensitive to degradation, especially by moisture, so do not keep it in damp places, like bathrooms, once the bottle is opened, and do not use old opened bottles of the capsules."

   
7.0

J.I.B. June 8, 2017

2 users found this comment helpful.

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For Constipation, Chronic "I have been on the medication for the last 7 days for chronic constipation and gastrointestinal pain. It has produced daily bowel movements in the form of diarrhea or very loose stools. However, it has also resulted in unbearable abdominal and intestinal pain, nausea, gas, disintention, bloating, inability to eat, intestinal gurgling and intestinal spasms that last 12 full hours after taking this medication. I was so hopeful that this would be effective and it has produced daily stools (diarrhea and loose stools) but at the compromise of feeling 10x's worse than I have felt not have any bowel movements or minimal bowel movements before taking this medication."

   
2.0

Mellie 39 June 3, 2017

10 users found this comment helpful.

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For Irritable Bowel Syndrome "I have tried to take this several times, with no success. My Dr Prescribed this for IBS-C. I can't take it in the morning for fear of incontinence. I took it last evening and woke up at 2am with liquid stools and severe diarhhea about every 15 minutes for about 6 hours. This medication will be going in the trash. So not worth it. I'd rather be constipated and take Dulcolax."

   
1.0

SRM146 May 22, 2017

10 users found this comment helpful.

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For Constipation, Chronic "I'm a 25 year old female who has had BMs every 7-9 days since I was 10 with no real answers. I had tried everything, nothing worked. I did not feel the sensation of "needing to go" despite the pain and discomfort in my abdomen and could only have a BM if I removed it myself with manual disimpaction. This was, of course, disgusting and very inconvenient. It eventually became normal for me and I had almost given up at ever finding treatment. I started taking Linzess 290 mcg nearly two weeks ago. Nothing happened for six days, and then I had a small, well-formed BM. I never had any explosive diarrhea that many others experience with this medication. My BMs are now every 1-2 days, small, and still sometimes have to be removed manually."

   
9.0

Heidimo (taken for less than 1 month) May 22, 2017

17 users found this comment helpful.

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For Irritable Bowel Syndrome "I started this a week ago because I was having incredibly intense cramps and nausea every time I needed to poop. I experienced massive diarrhea about an hour after I took it. I have other digestive issues, including Gastroparesis, GERD, and kidney problems, so I'm used to these issues. So I continued to take it and deal with the fallout diarrhea. Yesterday, I had the best day I've had in months. When I took the linzess, I didn't have the diarrhea and in fact had a normal day! I think this stuff might be effective if you can get past the initial diarrhea part and let it work for a week or so. I'm a little nervous about reports that it stops working after a month, but I'm going to see what happens."

   
8.0

Geiselgirl (taken for less than 1 month) May 21, 2017

9 users found this comment helpful.

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For Irritable Bowel Syndrome "I took Linzess earlier this year when I was constipated constantly from IBS and gastroparesis. It either gave me diarrhea or didn't work. Then my bowels normalized for a while so I quit taking it. About two weeks ago, the constipation started again, so I began taking it again. This time it was wonderful. I haven't had diarrhea; instead, it gives me a regular bowel movement each day and I don't have to stay at my house for several hours after I take it to make sure I stay near a bathroom. I'm on the higher dose of it. This is the way I had hoped it would work from the beginning."

   
9.0

Gastroparesis Girl (taken for 1 to 2 years) May 20, 2017

12 users found this comment helpful.

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For Constipation, Chronic "l took linzess this morning. l had taken linzess a long time ago and it had stopped working for me then. My doctor wanted me to try it again. Does not help at all. Now l am bloated and no bowel movement too. l know l have IBS but l tried this again to help me have bowel movements without worry. l will not try this again!!"

Anonymous (taken for less than 1 month) May 19, 2017

8 users found this comment helpful.

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For Irritable Bowel Syndrome "In my last review i praised my thoughts on Linzess. Unfortunately this med has lost its effectiveness for me. Suddenly I am all blocked up again. I am taking as directed and eat a good diet with plenty of exercise. Apparenty not for me long term."

   
3.0

Missmed (taken for 1 to 6 months) May 16, 2017

8 users found this comment helpful.

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For Constipation, Chronic "I am 40+ female! I thought I was going to live in misery the rest of my life! I had bowel movements every 3-5 days! I had so much bloating! I was cranky and had very little energy! I had constant pain in my back under my ribs! Since taking linzess, all of that is gone and I have had a bowel movement everyday! My energy is so much better! I am a different person! Thankful to God!"

   
9.0

Stacart (taken for 1 to 6 months) May 2, 2017

34 users found this comment helpful.

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For Constipation "I have found perfect combo for me. I take one Linzess (145 MCG) at least one hour before breakfast and a tbs of Citracel orange drink every morning. Linzess alone lost its effectiveness within a few weeks. I am 5' tall 110 lbs 75 years young. This combo keeps me as regular as clockwork for now."

   
9.0

Miss med April 21, 2017

14 users found this comment helpful.

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For Irritable Bowel Syndrome "I was diagnosed with IBS-C about a year and a half ago. No laxatives were working at all. I was first prescribed with linzess 145, that did nothing for me. Then my doc upped the dosage to 290. That helped a little more. Then he added Amatiza. I now have to take 2 Amatiza and a 290 for anything to happen for me. The bloating is insane and the water retention is unreal. Living my life constantly sick is no fun!"

   
5.0

JDailey April 16, 2017

13 users found this comment helpful.

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For Constipation, Chronic "I have been on this for about a week. After 20 years of complete idiopathic chronic constipation I had to take Mag Cit-rate or MOM every three days and wear a depends. It was necessary to stay alive and as I said 20 years (3 trips to Mayo Clinic and no help). I've not had any side effects that I am aware of yet. First morning I took it and had a bowel movement the next morning and it was a substantial and well formed movement. Later that night before bed, I had an urge and had another significant bowel movement. Second day same situation and had good bowel movement when I got up (within 2 hours). If this stays effective and no side effects emerge, my life has changed wonderfully forever. I could not travel before and had to wear a depends after magnesium as I never knew when I would get hit for about 16 hours. I have had no diarrhea with Linzess or bloating or pain. I hope prices go down or a generic occurs as I paid about $350.00 for 30 290mg capsules. Also, I pray that nothing occurs where this shows over time to have any negative side effects. I took Amitiza over 10 years ago and had agony and very poor results. I lost faith in all new drugs as they all panned out to have some serious problems so I waited on Linzess for over 5 years before trying it. No horror stories emerged and now, unless it stops working, I'm truly amazed after 20 + years of constant constipation. I didn't have over two or three Bm'S in 20 years without a magnesium product and they were getting more frequent for use with age. I'm happy to write this because I had given up and had considered having a colostomy or colectomy if I was a candidate. 10 stars for Linzess!"

   
10

Hornbeak (taken for 1 to 6 months) March 31, 2017

61 users found this comment helpful.

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For Constipation, Chronic "Linzess 145mcg gave me explosive diarrhea for hours. I thought I must have eaten something bad so I waited a day and took Linzess again and about 2 1/2 hours later it happened again and lasted 5 hours. Obviously not for me. I strongly suggest you're at home the first time you take this just in case."

   
1.0

goldengurl (taken for less than 1 month) March 29, 2017

33 users found this comment helpful.

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For Constipation, Chronic "I am 68 years old and a recently retired registered nurse. I have had problems off and on with irregularity most of my adult life. I used OTC laxatives sporadically and ate a lot of roughage. 6 months ago, I had a minimally invasive mitral valve repair, followed by a heart attack and stroke 6 days post-op, and an emergency cardiac stent. I had been prescribed Ativan for anxiety and Tramadol for pain as well as Amiodarone. All of these contributed to chronic constipation. A few months back, I thought I was having a bowel obstruction. My primary physician recently prescribed Linzess. Within hours, I experienced a bowel movement without STRAINING for the 1st time in 6 months. It was the best day I've had since last August."

   
10

Gratefuljcc March 29, 2017

35 users found this comment helpful.

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