User Reviews for Amitiza
Amitiza has an average rating of 5.6 out of 10 from a total of 267 reviews on Drugs.com. 44% of reviewers reported a positive experience, while 39% reported a negative experience.
|Chronic Idiopathic Constipation||161 reviews||5 medications|
|Irritable Bowel Syndrome with Constipation||74 reviews||5 medications|
|Opioid-Induced Constipation||32 reviews||4 medications|
|Add your review|
Reviews for Amitiza
For Chronic Idiopathic Constipation "I have has chronic IBS with constipation forever. At one point, I thought I had an obstruction, but didn't. I went to a gastroenterologist and she prescribed 8mcg of Amitiza twice per day. It worked pretty quickly, but then didn't seem to anymore. I had a lot of the side effects that other people mentioned including gas, bloating, and bad stomach pains. I now take two 24 mcgs per day and figured out that if I take one before bed and one an hour before I get up, I don't have major issues. I go every morning completely and feel great for the rest of the day. I hope this helps other people trying this medication."
For Opioid-Induced Constipation "I'd never been regular, my whole life, it was always a problem that I was lucky if it resolved itself every 3 or 4 days, but then once I aged and my rheumatoid arthritis advanced to a debilitating degree, I had to go on opiates...oh dear. 7-8 days or even more of being bound up became the norm. It was REALLY painful! The only way I could help myself was to stop taking my pain meds and overdose on laxatives and enemas every few days. That usually worked within 24 hrs, but it really isn't good for you. I finally confessed to my gastroenterologist that this was going on and he prescribed me Amitiza. It took a week to work for me, but now I have the exact opposite problem. I'm on 24 mcg 2x daily. I think maybe it needs to be just once!"
Frequently asked questions
- Amitiza - how long does it take to work? Is it better to take after dinner?
- Which drugs cause opioid-induced constipation?
For Chronic Idiopathic Constipation "Thank God for modern medicine! Constipation may seem to those who don't suffer from it in its severe form to be a minor issue, it is NOT! When going to the bathroom induces fear and anger because you know that you will spend the next 45 minutes suffering doing what others take for granted it's time to get help. After a year of using Fleets and OTC meds which did nothing I was finally given Amitiza and It was a little miracle. Don't suffer, demand this medication don't let your MD's tell you to take OTC meds which do nothing or next to nothing. I had to suffer a fissure before finally getting this simple solution to a horrible problem. Don't wait until it's a very serious medical problem deal with it now."
For Irritable Bowel Syndrome with Constipation "I have Irritable Bowel Syndrome- Constipation and have tried everything out there. They either didn't work or had ridiculous side effects that outnumbered the advantages. Amitiza is the best medicine I have ever taken. I have very severe constipation and take 24mcg 2x/daily. I went from no bowel motions to going once every other day on average. Advice...take it with food. The only side effect I have is crazy nausea and a horrid headache if I take it on an empty stomach. Also it is very expensive and can have a hefty co-pay. Amitiza has a website where you will get a free card to cover your co-pay. I went from $25 out of pocket to $0!"
Are you taking this medicine?
For Chronic Idiopathic Constipation "I have had Chronic idiopathic Constipation all my life. I am a 64 year old female. I had hemorrhoid surgery at 18 and again at 28. I remember as a young girl straining to have a bowel movement, I have tried all kinds of laxatives lubricant, fiber, stimulants, motility drugs, and everything in between. I have been taking Amitiza for 8 days and I've had 6 BM'S. WONDERFUL, LIFE CHANGING MEDICATION I have had no side effectsand my insurance covers most of the drug. I am so excited I don't know what to do.I would advise anyone with CIC to give this drug I tried. it has been a lifesaver for me I'm so glad I found out about it"
For Irritable Bowel Syndrome with Constipation "After reading all of these negative reviews I decided I need to give my 2 cents in. I have suffered with constipation and stomach aches my entire life and recently it went from bad to worse and I finally told my doctor that I needed to do something. He originally prescribed Linzess but my insurance would only cover that after trying Amitiza. I have been taking Amitiza as a laxative for a week and it is a miracle, it works so well! I take two MCG pills a day. I have found 1 at night after dinner and 1 in the morning after breakfast works great. I am having normal and complete movements for the first time in years (usually I have diarrhea from taking laxatives or rocks)...it was never normal or complete. I do get a little nauseated sometimes after I take Amitiza but it does not compare to the nausea I get from other laxatives I have tried or being backed up. I have been drinking mint tea and it really helps. This drug is a miracle."
For Chronic Idiopathic Constipation "I am a 25 year old female. I have been constipated since I was a baby and nobody knew why. I always had to strain to go to the bathroom. As a matter of fact I had to mentally prepare. I had to focus on my breathing to try to cope with the pain and fear of going to the bathroom. Sometimes it would take me 2 hours for nothing. I have used Amitiza for 18 months now AND IF THEY EVER TOOK IT AWAY I WOULD START A RIOT. I go to the bathroom about 4 times a week. No pain,no strain, and its soft and not hard. My stomach is so much flatter. I can see I actually have a shape. I lost 10 pounds of waste the first 2 weeks. I feel lighter and happy. Going to the bathroom is a breeze. Sometimes I get nausea. But the cons are light compared to the pro."
For Chronic Idiopathic Constipation "Amitiza has worked great for me every time that I have taken it. I only have to take it as needed. It works very fast! Usually between 30 min-1hour. Longest it has ever taken was 3 hours. No cramping or distention. Only problem is the diarrhea, sometimes explosive. Still better than being constipated to the point of impaction though. Word of caution: If you take it, beware of passing gas...it sometimes isn't just gas you are feeling...lets just say you may be in a bit of a messy situation if you aren't careful!"
For Chronic Idiopathic Constipation "I have had opioid-related constipation for approximately the last 6 months. I had tried Colace, Miralax, apricots, prunes - anything I knew of that might help. I eventually ended up using enemas every few days to make sure that I went to the bathroom because it was starting to cause me terrible stomach pains. I have only been on Amitiza for a little over a week, and it has only helped me go to the bathroom one time, and it really wasn't like a complete BM. After taking it, I have a severe headache and nausea. Is this just a phase of the beginning of taking this medication? I don't know, but I can't deal with this being sick constantly. All I want to do is be in bed because moving around makes me feel like I'm going to projectile vomit. I know this might not be a problem for everyone, but for me...this medicine is not helping but only making things worse."
For Irritable Bowel Syndrome with Constipation "I've had IBS-C for at least 2 years. In the last year, it has become increasingly worse which resulted in me being diagnosed with pelvic floor dysfunction. Like most of you, I could barely go...nothing seemed to help: Miralax, Philips, etc. I was resuming to using enemas a few times a week just to get some relief. Because of this, I was feeling tired all the time, moody and having horrible headaches. It left me feeling awful. I recently started this medicine, and it has been a God-send. I went from never being able to go on my own to at least once a day. I take it with food and water. I read the reviews on here beforehand, so I made sure to follow what others said. The first day I took it, I felt a little nauseous, but haven't since."
For Chronic Idiopathic Constipation "I recently started Amitiza at the 24mcg dose twice a day for terrible constipation not resolved with tons of water, veggies, fruits, flax, chia, bottles of Miralax, or Linzess. I have taken it for 4.5 days with NO results at all. How long is this supposed to take to work? I have the side effects of nausea, stomach cramps, bloating, hot flashes then so cold I shiver, body aches like I am coming down with the flu, joint pain. And believe me, I would put up with all of this if I could just go! But nothing is happening. I even increased my fluid intake to 3L per day, which is ridiculous. Does anyone have suggestions out there?"
For Chronic Idiopathic Constipation "I absolutely love this medicine. Was so constipated that all I did was sleep. Was miserably "full" with Bowel Motion maybe once every 1 to 2 weeks. Nothing else worked for me. Slight nausea sometimes (which is nothing). My energy level is restored. I thank God for giving man the knowledge to make this medicine."
For Chronic Idiopathic Constipation "After several years of regular constipation and laxative use my doctor prescribed Amitiza. I took it at 6 and by 10:30 it was working. I've been taking 24mg twice daily but I think I'll cut back to only once a day because sometimes I'm nervous about leaving my house. It works too well and very fast. "
For Chronic Idiopathic Constipation "I have been taking this medicine for about two weeks now and I must say it is heaven sent. There's nothing worse than being compacted with waste and having that constipation sensation constantly. What prompted me to invest in this "life saver" was one day like some of you I went to use the restroom and yet again as usual I was constipated so I was frustrated and everything else so I forced my bowel movement and when I finished I was bleeding. I made an appointment with doctor and today I'm so glad I did. So, so, so happy now."
For Chronic Idiopathic Constipation "my doctor put me on Amitiza yesterday. 2 hours after taking this medication I had a BM. I had gone a week without a BM. I have suffered from Constipation all of my life. Normally I would have one BM a week on a good week two. I was always in pain, full and just uncomfortable. I cant tell you how good it feels to be "normal" I have had two more BM's today. For some this may not seem exciting but only if you have suffered from Chronic Constipation would you understand. I would recommend this to any one., I have not suffered any of the side effects that others have talked about for me it has been a God send. The only negative comment I would have is the price as insurance does not cover it and it was over $300.00 a month"
For Chronic Idiopathic Constipation "I've been taking this medicine for about 6 months, and it has made a world of a difference. I've had constipation for over 8 years, I'm in my late 20s, healthy, female, & moderately active. Things that normally would give others runny diarrhea, like prune juice, I would barely see any effect. After being tired of painful amounts of fiber intake & OTC stool softeners that didn't help enough, my doctor put me on this twice a day, & it works great. I had few side effects, and only for about a week."
For Chronic Idiopathic Constipation "I was in the hospital for a week in January with colitis. Was prescribed Amitiza when I was released, 2 capsules per day of 240mcg. I started taking the med. and after 3 days I was having very lose bowel movements 4 or 5 times a day. I had also been told to go on the Mediterranean diet. I only had nausea the first couple of days. I finally learned to take the med. only once a day and did so for a week. I started skipping the med for 1 day and then 2 days. I started having regular bowel movements every morning so (with the Dr.'s approval) I only take the medicine as needed. If you follow the directions VERY CAREFULLY some of the symptoms will go away, I am a 79 year old extremely active man."
For Chronic Idiopathic Constipation "I am a 27-year old female who suffers from life-long chronic idiopathic constipation. Much like most of you, I have tried everything the FDA has approved under the sun. Ran out of options and was prescribed Amitiza. I took two capsules the first day and was the most sick I have ever been. Projectile vomiting, shaking, faintness, heart palpitations, tight chest, and liquid stool. I was close to calling 911, but vomiting brought me back to life, so to speak. I completely emptied my bowels, the price of becoming that ill was not worth it. I have stopped taking it and am so heartbroken. I was hoping this would be it. The cure. I wasted so much money on the prescription."
For Irritable Bowel Syndrome with Constipation "I've been taking 8mcg Amitiza twice a day, for two months, to treat Irritable Bowel Syndrome. Finally! A Dr. who actually listened to me and provided a solution instead of blaming me for the GI/bowel problems. (i.e., "You need more fiber," "It's your nerves," or "It's caused by the NSAIDS you take."). Almost 40 years of daily chronic painful bloating, constipation & pain under my left ribcage is almost gone, (I'm 50.) It did take a few weeks to adjust to it. By that, I mean: 1.) Discovering that taking Fiber Supplements with the prescription caused painful gas/bloating, 2.) Determining exactly how much food/drink to ingest with each dose, to avoid gas/bloating or a headache & 3.) Remembering to take it with a meal. I'd give it a 10 if there was 0 bloating and no headaches."
For Irritable Bowel Syndrome with Constipation "I am a 30 year old woman who has been suffering from IBS-C since before my teen years. This is the only pill that has ever worked for me. There have been times where I would go off the medication because it is rather pricey. And I can tell you, I regret it every time. My IBS-C is so bad to the point where I will go weeks without any relief. And then when I am able to go, I get ridiculously sick for hours prior to the BM. The stomach pains I feel are worse than labor pains, and I would know since I have been through child birth. I only need to take one 8mcg tablet a day (with food, typically lunch time) and I stay regular. If you are struggling with a disease like this, amitiza is totally worth a shot! What do you have to lose?"
For Chronic Idiopathic Constipation "I am 55 and have been living with IBS-C for the last 10 yrs. My doctor started me on Amitiza a week ago. I am on 24mcg twice daily. I took my initial dose at the beginning of a meal. It caused pretty severe nausea, but really cleaned me out with 4 or 5 small BM's ranging from normal to explosive diarrhea. I have taken each subsequent dose in the middle of a meal, and have had the most normal bowel pattern than I have had in years. No more nausea, reflux, cramping or gas. This med is allowing me to have several small BM's daily, as opposed to using laxatives, which is miserable. I hope it continues to work! I'm using samples from my doctor right now. Not sure if insurance is going to cover it."
For Irritable Bowel Syndrome with Constipation "I developed Irritable Bowel Syndrome-C and chronic constipation after a C-section. I now take Amitiza 24mcg 2x per day. I've been on it for about 10 months. It works fantastic. I can "go" at least once a day now. Amitiza draws fluid from your body to increase bowel movement (I can actually hear it working) so it is important to drink a lot of water and eat before or immediately after. I've noticed that if I don't drink a lot of water, nausea will develop. In addition, IBS-C has caused me to change my diet and exercise. That helped a lot too. NOTE-- If the prescription costs a lot, even with insurance, Amitiza offers a discount card online."
For Chronic Idiopathic Constipation "I have had constipation my entire life (I'm nearly 64). My father (deceased) was a Physician & kept things 'working' with various medications. As an adult, and after being diagnosed with Lupus in '84, it gradually worsened. I had tried everything. My normal routine was a bowel movement every 5-7 days, and then it was difficult. I have been hospitalized for impaction.In the more recent years I have been on a Miralax type product twice a day & 24mcg of Amitiza (once or twice a day). Amitiza is the ONLY thing that has ever worked. I can't remember how long it took to 'kick' in, but after decades of food not transitioning through my system, I was patient. I couldn't function without it. I feel somewhat normal now. AMAZING!"
For Chronic Idiopathic Constipation "As a survivor of very severe anorexia, I had renal failure and am now not able to produce the correct mucus or "lubrication" in my intestines. This causes bowel movements to be infrequent and painful. Amitiza is a god send. Works just like it should. Was on 16 mcg twice a day but was just put on 24 mcg twice a day with 40mg Zegrid. Not sure which one is causing nausea, but Amitiza never did it before. Has made bowel movements much easier."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
More about Amitiza (lubiprostone)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- Support group
- FDA approval history
- Drug class: chloride channel activators
- En español
For Chronic Idiopathic Constipation "I've had chronic constipation all my adult life. Tried Linzess, it worked for a month then stopped. Doctor started me on Amitiza (24 mg) and it is a miracle. I've been on for four months now. After a life of 7-10 days between bowel motions, I now go comfortably 3-4 times per week. No pain, very little gas. It's a miracle for me."