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Amitiza User Reviews & Ratings (Page 4)

Amitiza has an average rating of 5.6 out of 10 from a total of 270 reviews on Drugs.com. 42% of reviewers reported a positive experience, while 39% reported a negative experience.

Reviews for Amitiza

Commonly mentioned side effects
  • Lil...
  • September 26, 2015

For Chronic Idiopathic Constipation "My doctor put me on the 24s twice a day with a meal. Despite always taking it correctly, it always gives me unbearable nausea and occasionally diarrhea. For me personally, the side effects make this medication very unbearable. However, I gave it a decent rating because it certainly gets things moving along. The first day I took it, I passed stool 5 times, which seemed excessive. Overall, it's up to you to decide if you feel better or worse after taking it."

8 / 10
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33 Report
  • Anonymous
  • January 6, 2012

For Irritable Bowel Syndrome with Constipation "I had tried everything for irritable bowel syndrome -- colonic treatments; stool softeners; magnesium; stimulant laxatives. The list is endless, but until I went on Amitiza, nothing worked well. I take the larger dosage at bedtime -- very mild nausea occasionally, but at least one bowel movement daily. This medication has literally been a life-saver."

9 / 10
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44 Report
  • Anonymous
  • May 22, 2009

For Chronic Idiopathic Constipation "Had side effects - not even understanding it was from this medication. Went to doctors many times with flu-like symptoms and breathing problems with chest pains. After stopping this medication, after being on it for months, it has now been a week, my breathing still has not returned to normal as of yet. PLEASE, if you have any flu-like symptoms, breathing problems, or even seem to just have a change in your voice, stop taking this medicine and see your doctor."

1 / 10
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51 Report

Frequently asked questions

  • Anonymous
  • October 21, 2009

For Chronic Idiopathic Constipation "I have had very severe chronic constipation for over two years that has just seemed to get worse and worse over time. I've tried Amitiza on a few occasions over the last couple of years, and each time has been an awful experience. It works, but it takes about 3 days, and those 3 days are unbearable. Horrible gas and bloating, headaches, cramps, nausea, not to mention the pain in my back and sides from the severe bloating. I gave a friend some of my samples, and it worked wonders for her, she had none of those side effects. Everyone is different, it's always worth a try."

1 / 10
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48 Report
  • No...
  • April 14, 2015

For Irritable Bowel Syndrome with Constipation "I have been on Rx Miralax for years, due to a two-decade-long eating disorder. The Miralax works great, but for some reason, my GI wanted to put me on Linzess. He gave me samples, and insurance didn't cover it. They said I had to try Amitiza first. The Linzess didn't work (horrible bloating, cramps, no movement), and the Amitiza is almost worse. I had to call out of work today because of it. I was awake all night, up and down, kept getting sick. 14ish hours after taking the medicine, I'm having very small movements. Strongly debating calling the office and telling them I'm going back on Miralax, and that's it."

1 / 10
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35 Report

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  • Sta...
  • January 9, 2009

For Chronic Idiopathic Constipation "I have been on pain medicines for the last 6 and 1/2 years. My doctor finally gave me some samples of Amitiza. When I haven't gone in so many days, I just take two pills late in the evening, and they work great in the morning. I haven't noticed any side effects at all."

10 / 10
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46 Report
  • Mou...
  • Taken for 1 to 6 months
  • February 27, 2020

For Chronic Idiopathic Constipation "I was taking Linzess with total success. Then insurance wanted me to try Amitiza. Then I became twice as constipated and had extreme fatigue, abdominal cramps that felt like labor pains, headaches, and severe dehydration, and my movements went from 3 to 4 days to 5 to 7 days. I became toxic. I will never take that Amitiza again. I swear it is nothing more than a placebo. Bad stuff. I now have to reschedule my colonoscopy because of a blockage that could have been prevented. My life and health are a joke to Fidelis insurance."

1 / 10
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  • Meg...
  • Taken for less than 1 month
  • August 28, 2016

For Opioid-Induced Constipation "I have opiate-induced constipation from narcotic pain killers. My doctor gave me samples of Manitoba, and it worked great. I didn't have any side effects other than cramping, which is to be expected with any laxative. It worked within 2 hours and continued to work throughout the rest of the day. I would definitely recommend taking this on a day you have nothing to do. It causes a little gas and stomach cramps that feel like you're gonna have diarrhea. But it definitely does the job. I also had a little nausea after taking it, but it was worth it. Especially if you have been dealing with chronic constipation for a while. Anything is better than the constant bloating and pain associated with constipation."

8 / 10
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28 Report
  • Bel...
  • Taken for less than 1 month
  • June 7, 2012

For Chronic Idiopathic Constipation "I've suffered from constipation for about 10 years now. I would use a laxative once or twice a week. Tired of laxatives, so the doctor prescribed Amitiza. The first 2 days, I suffered from severe nausea and had to lay in bed for an hour or so until it passed. Then I had extreme diarrhea that lasted the whole day. So far, it seems that I'm only experiencing light nausea with the first dose, which seems to subside when I fill my stomach with food. It has been a full week now that I've been taking it and have yet to have a full bowel movement. I have constant gas and pains. I feel like I have to have a movement, but when I go to the bathroom, I find I still have to strain and nothing really comes out."

4 / 10
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38 Report
  • LYB...
  • Taken for less than 1 month
  • November 5, 2016

For Chronic Idiopathic Constipation "I am in my early 60s. Have had chronic constipation ever since childhood (2 BMs per week), but it became much worse in the last couple of years (up to 2 weeks without a BM). After more than a year of trying to find the optimal amount of Miralax to take per day per GI doctor's instructions, and when to also include stool softeners, I was doing okay (BM every 4 or 5 days), but had occasional leakage. I started Amitiza two weeks ago at my internist's suggestion, two 8 mg pills twice a day. It was like a miracle the first week - small to medium daily movements and a couple of large ones. No side effects. But now it stopped working. It has been 7 days with no BM. The last 2 days I took 24 mg. Also ate prunes and took stool softeners. Nothing yet."

6 / 10
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  • INm...
  • Taken for less than 1 month
  • February 14, 2013

For Irritable Bowel Syndrome with Constipation "I have irritable bowel syndrome, Crohn's disease, as well as colon issues. My GI started me on Amitiza about 10 days ago. So far, it has been great. I do have some cramping a little after a pill, but not compared to the constipation cramping that I have had on and off for 15 years. I was lucky he gave me a sample pack good for a month, so now I just have to hope my insurance picks it up next month."

9 / 10
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39 Report
  • Jad...
  • Taken for less than 1 month
  • May 2, 2017

For Opioid-Induced Constipation "My gastroenterologist prescribed Amitiza to help with constipation caused by a medication I am taking. I took one capsule (24 mcg) daily for five days, then began taking two (48 mcg) daily (too big a dose?). The medication worked wonderfully to help relieve the constipation, but the side effects I am experiencing may cause me to stop taking it. I am having headaches, runny nose, fatigue, overall 'bad' feeling, muscle pain, chills, nausea, and a sensation of almost passing out. I consider these side effects pretty drastic. It's possible they will go away or minimize if I continue to take the capsules, but I'm not sure I'm willing to risk it."

6 / 10
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  • Jo ...
  • May 16, 2016

For Chronic Idiopathic Constipation "I'm just writing to tell people if Amitiza isn't working for you, DO NOT switch to Linzess! It worked great in the beginning, but for me and thousands of people complaining online... it just stopped working. I actually went from taking one 145 mcg capsule to THREE, and nothing! Linzess sucks."

2 / 10
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  • Anonymous
  • September 20, 2012

For Chronic Idiopathic Constipation "I started taking Amitiza a month ago. I am on the 24 mg. It works sometimes, but I am experiencing side effects that I didn't think resulted from this medication until I read some of the reviews. I have trouble taking in breaths, coughing, severe headaches, nausea, but most of all, bloating and gas. Before the medication, while being constipated, I could still button up my pants. Now that I've started the medicine, it's a struggle due to bloating."

5 / 10
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  • Anonymous
  • October 6, 2016

For Opioid-Induced Constipation "Absolutely do NOT take Amitiza if you're on Methadone. I thought I would die! After my first symptom of feeling like I was having a heart attack, I immediately went to the website, and what did I see? 'Talk to your doctor if taking methadone.' OMG, the severe side effects are not worth it when there are so many other medications out there."

1 / 10
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  • hon...
  • Taken for 2 to 5 years
  • September 24, 2019

For Chronic Idiopathic Constipation "I have been taking Amitiza 24 mcg twice a day for several years. I also take psyllium fiber and drink water up to 2 quarts a day. Since my work does not support a lot of walking, I tend to get abdominal bloating in the afternoon due to incomplete bowel emptying and inactivity. When my stool becomes dark brown, I may experience diarrhea as my colon is attempting to move hard stool. When my stool is soft formed and a light tan color, I experience a feeling of complete emptying and no abdominal bloating or diarrhea. This is a daily challenge to ensure sufficient exercise, water intake, and fiber-rich and roughage-producing foods. I feel that the medication would be more effective if the dosage could be titrated or time-released to meet individual patient needs."

8 / 10
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  • lon...
  • July 7, 2009

For Chronic Idiopathic Constipation "I am 71 and have had constipation all of my life. I've tried OTC products (all of them) and even some prescription products. I take 4 of this per week with plenty of water. More gives me some cramps. However, my constipation is finally under control. It isn't easy, but I do get results about 4 times a week. That beats 1 or 2 with a lot of bleeding from strain. I may increase to 7 times per week and see if the cramping stops. I have a super long colon, which has caused the chronic constipation."

8 / 10
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  • Anonymous
  • March 14, 2008

For Chronic Idiopathic Constipation "A person has to decide if it is worth the less serious side effects of nausea and headache, and I have to say that it is. It is brief and, therefore, I feel that the alternative is much worse. It has only been a full week, and I am hoping these less serious side effects will subside eventually when I get used to taking it on a regular basis."

8 / 10
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53 Report
  • Nee...
  • December 28, 2014

For Chronic Idiopathic Constipation "I took 24 mcg of Amitiza for 6 days, twice a day. I got a pretty bad reaction from this. I had dry mouth, lightheadedness, my face was always warm, stomach aches, loss of appetite, severe anxiety, and nausea. I've come to the conclusion that the 24 mcg twice a day was far too much for my body. I weigh 117 pounds, and I don't think my body could handle that amount. If anyone is experiencing these side effects, don't take it, make another appointment with your doctor to see if the dosage is too much. Also, if you have had a loss of appetite like myself, make sure to get enough sugar in your system, I had a hypoglycemic attack. Drink ginger ale, or eat if you can."

2 / 10
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32 Report
  • aer...
  • Taken for less than 1 month
  • August 7, 2012

For Chronic Idiopathic Constipation "I have been on this for about a week. First few days, was amazed. Before this medicine, I would do enemas every week or so due to pain, etc. The day after I took this medicine, I went three times, once after every meal. Wow! Same for the next few days. Side effects: majorly tired, headaches that develop into migraines by the end of the day, weird feeling in chest and throat, breathing funny (like a bad cold), and VERY nauseated until I have a movement. Also, the last few days, only having a movement every other day. So don't know what is going on. Need to try increasing the water and see how that goes. Don't know if normal bowel movements are worth all this, plus, it seems to not work as well as it did a few days ago."

5 / 10
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  • tif...
  • Taken for less than 1 month
  • November 25, 2012

For Chronic Idiopathic Constipation "I take the 24 mg twice a day after having severe constipation post-chemo and multiple abdominal surgeries. It takes a couple of days for it to cause a movement, but when it does, it's unbelievable how much it works! I have felt the nausea and headaches, but didn't realize it was caused by the Amitiza. I'm so thankful to have this medicine!"

9 / 10
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40 Report
  • FIN...
  • February 12, 2018

For Chronic Idiopathic Constipation "I have been severely constipated for years after 20 years of chronic diarrhea. Have had to resort to enemas and laxatives just to get some relief. Was on Linzess 290 for a year and a half, and it was so inconsistent when it worked. Started Amitiza 24 mcg a couple of months ago. You definitely have to eat while taking it, literally. I only have to take it once a day now, and I feel like it is a miracle. I just hope it doesn't stop working. I am finally feeling normal and not sluggish and miserable anymore. It is quite expensive, as my insurance pays very little, and I'm out $259 per month. It's definitely worth it to me. I was probably spending more than that on OTC stuff anyway."

10 / 10
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  • Ano...
  • October 14, 2009

For Irritable Bowel Syndrome with Constipation "I used this medication. After the second pill, I began to feel an awful feeling in my stomach that worked itself all the way up to my throat. My tongue swelled, and I had to take a Benadryl to counteract this allergic reaction. Just wanted to alert others to this just in case it happens to them."

2 / 10
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41 Report
  • jm1...
  • July 19, 2011

For Irritable Bowel Syndrome with Constipation "Before taking Amitiza, I had stomach pain every single time I ate, suffered from severe constipation, had gas and bloating. I take 24 mg twice a day, and my pain has completely diminished, but I still have severe constipation and still get bloated every time I eat. The medicine does help, but not completely."

7 / 10
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36 Report
  • Mar...
  • August 30, 2015

For Irritable Bowel Syndrome with Constipation "I tried the samples my dr sent me home with. It gave me some of the worst stomach aches of my life. And I didn't go to the bathroom any more than I normally do. I hated this medication, it made me feel much worse."

1 / 10
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30 Report

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