Amitiza Dosage
Generic name: lubiprostone 8ug
Dosage form: capsule, gelatin coated
Drug class: Chloride channel activators
Medically reviewed by Drugs.com. Last updated on Apr 12, 2021.
Recommended Dosage
The recommended oral dosage of Amitiza by indication and adjustments for patients with moderate (Child Pugh Class B) and severe (Child Pugh Class C) hepatic impairment are shown in Table 1.
CIC and OIC | IBS-C | |
---|---|---|
|
||
Recommended Adult Dosage Regimen | 24 mcg twice daily | 8 mcg twice daily |
Dosage Adjustment for Hepatic Impairment [see Use in Specific Populations (8.6)] | Moderate Impairment (Child-Pugh Class B): 16 mcg twice daily* |
Moderate Impairment (Child-Pugh Class B): No adjustment necessary |
Severe Impairment (Child-Pugh Class C): 8 mcg twice daily* |
Severe Impairment (Child-Pugh Class C): 8 mcg once daily* |
Frequently asked questions
More about Amitiza (lubiprostone)
- Side effects
- Drug interactions
- During pregnancy or Breastfeeding
- Reviews (266)
- Drug images
- Compare alternatives
- Pricing & coupons
- Generic availability
- En español
- Drug class: chloride channel activators
- FDA approval history
Patient resources
Professional resources
Related treatment guides
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.