Amitiza Dosage
Generic name: LUBIPROSTONE 8ug
Dosage form: capsule, gelatin coated
Drug class: Chloride channel activators
Medically reviewed by Drugs.com. Last updated on Mar 12, 2025.
Recommended Dosage
The recommended oral dosage of Amitiza by indication and adjustments for patients with moderate (Child Pugh Class B) and severe (Child Pugh Class C) hepatic impairment are shown in Table 1.
| CIC and OIC | IBS-C | |
|---|---|---|
|
||
| Recommended Adult Dosage Regimen | 24 mcg twice daily | 8 mcg twice daily |
| Dosage Adjustment for Hepatic Impairment | Moderate Impairment (Child-Pugh Class B): 16 mcg twice daily* |
Moderate Impairment (Child-Pugh Class B): No adjustment necessary |
| Severe Impairment (Child-Pugh Class C): 8 mcg twice daily* |
Severe Impairment (Child-Pugh Class C): 8 mcg once daily* |
|
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Further information
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