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Medications for Type 2 Diabetes

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Janumet 6.3 66 reviews for Janumet to treat Type 2 Diabetes Rx B N X
Generic name:
metformin / sitagliptin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
metformin / sitagliptin 6.2 76 reviews for metformin / sitagliptin to treat Type 2 Diabetes Rx B N X
Generic name:
metformin / sitagliptin systemic
Brand names:
Janumet, Janumet XR, Zituvimet, Zituvimet XR
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
glimepiride / pioglitazone 1.0 2 reviews for glimepiride / pioglitazone to treat Type 2 Diabetes Rx C N X
Generic name:
glimepiride / pioglitazone systemic
Brand name:
Duetact
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
glyburide / metformin 4.8 5 reviews for glyburide / metformin to treat Type 2 Diabetes Rx B N X
Generic name:
glyburide / metformin systemic
Brand name:
Glucovance
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Xigduo XR 7.3 17 reviews for Xigduo XR to treat Type 2 Diabetes Rx C N X
Generic name:
dapagliflozin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
dapagliflozin / metformin 7.3 17 reviews for dapagliflozin / metformin to treat Type 2 Diabetes Rx C N X
Generic name:
dapagliflozin / metformin systemic
Brand name:
Xigduo XR
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
empagliflozin / metformin 5.6 37 reviews for empagliflozin / metformin to treat Type 2 Diabetes Rx C N X
Generic name:
empagliflozin / metformin systemic
Brand names:
Synjardy, Synjardy XR
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
glipizide / metformin 3.5 2 reviews for glipizide / metformin to treat Type 2 Diabetes Rx C N X
Generic name:
glipizide / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Glucovance 7.5 2 reviews for Glucovance to treat Type 2 Diabetes Rx B N X
Generic name:
glyburide / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Janumet XR 5.7 3 reviews for Janumet XR to treat Type 2 Diabetes Rx B N X
Generic name:
metformin / sitagliptin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Jentadueto 5.9 15 reviews for Jentadueto to treat Type 2 Diabetes Rx B N X
Generic name:
linagliptin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Kombiglyze XR 4.7 16 reviews for Kombiglyze XR to treat Type 2 Diabetes Rx B N X
Generic name:
metformin / saxagliptin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
metformin / pioglitazone 6.4 5 reviews for metformin / pioglitazone to treat Type 2 Diabetes Rx C N X
Generic name:
metformin / pioglitazone systemic
Brand name:
ActoPlus Met
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
metformin / saxagliptin 4.7 16 reviews for metformin / saxagliptin to treat Type 2 Diabetes Rx B N X
Generic name:
metformin / saxagliptin systemic
Brand name:
Kombiglyze XR
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Soliqua 4.5 17 reviews for Soliqua to treat Type 2 Diabetes Rx N X
Generic name:
insulin glargine / lixisenatide systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Synjardy 6.3 24 reviews for Synjardy to treat Type 2 Diabetes Rx C N X
Generic name:
empagliflozin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Xultophy 9.3 3 reviews for Xultophy to treat Type 2 Diabetes Rx N X
Generic name:
insulin degludec / liraglutide systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ActoPlus Met 6.4 5 reviews for ActoPlus Met to treat Type 2 Diabetes Rx C N X
Generic name:
metformin / pioglitazone systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
alogliptin / metformin 5.0 2 reviews for alogliptin / metformin to treat Type 2 Diabetes Rx B N X
Generic name:
alogliptin / metformin systemic
Brand name:
Kazano
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
alogliptin / pioglitazone 3.5 2 reviews for alogliptin / pioglitazone to treat Type 2 Diabetes Rx C N X
Generic name:
alogliptin / pioglitazone systemic
Brand name:
Oseni
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
canagliflozin / metformin 2.5 2 reviews for canagliflozin / metformin to treat Type 2 Diabetes Rx C N X
Generic name:
canagliflozin / metformin systemic
Brand names:
Invokamet, Invokamet XR
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
dapagliflozin / saxagliptin Rate Add review Rx N X
Generic name:
dapagliflozin / saxagliptin systemic
Brand name:
Qtern
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
Duetact Rate Add review Rx C N X
Generic name:
glimepiride / pioglitazone systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
empagliflozin / linagliptin 6.7 23 reviews for empagliflozin / linagliptin to treat Type 2 Diabetes Rx C N X
Generic name:
empagliflozin / linagliptin systemic
Brand name:
Glyxambi
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
empagliflozin / linagliptin / metformin Rate Add review Rx N X
Generic name:
empagliflozin / linagliptin / metformin systemic
Brand name:
Trijardy XR
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
ertugliflozin / metformin Rate Add review Rx N X
Generic name:
ertugliflozin / metformin systemic
Brand name:
Segluromet
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
ertugliflozin / sitagliptin 9.0 1 review for ertugliflozin / sitagliptin to treat Type 2 Diabetes Rx N X
Generic name:
ertugliflozin / sitagliptin systemic
Brand name:
Steglujan
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
Glyxambi 6.7 23 reviews for Glyxambi to treat Type 2 Diabetes Rx C N X
Generic name:
empagliflozin / linagliptin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
insulin degludec / liraglutide 9.3 3 reviews for insulin degludec / liraglutide to treat Type 2 Diabetes Rx N X
Generic name:
insulin degludec / liraglutide systemic
Brand name:
Xultophy
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
insulin glargine / lixisenatide 4.5 17 reviews for insulin glargine / lixisenatide to treat Type 2 Diabetes Rx N X
Generic name:
insulin glargine / lixisenatide systemic
Brand name:
Soliqua
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
Invokamet 2.5 2 reviews for Invokamet to treat Type 2 Diabetes Rx C N X
Generic name:
canagliflozin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Invokamet XR Rate Add review Rx C N X
Generic name:
canagliflozin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Jentadueto XR 9.0 2 reviews for Jentadueto XR to treat Type 2 Diabetes Rx B N X
Generic name:
linagliptin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Kazano 5.0 2 reviews for Kazano to treat Type 2 Diabetes Rx B N X
Generic name:
alogliptin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
linagliptin / metformin 6.3 17 reviews for linagliptin / metformin to treat Type 2 Diabetes Rx B N X
Generic name:
linagliptin / metformin systemic
Brand names:
Jentadueto, Jentadueto XR
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
Oseni 3.5 2 reviews for Oseni to treat Type 2 Diabetes Rx C N X
Generic name:
alogliptin / pioglitazone systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Qtern Rate Add review Rx N X
Generic name:
dapagliflozin / saxagliptin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Segluromet Rate Add review Rx N X
Generic name:
ertugliflozin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Steglujan 9.0 1 review for Steglujan to treat Type 2 Diabetes Rx N X
Generic name:
ertugliflozin / sitagliptin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Synjardy XR 4.9 11 reviews for Synjardy XR to treat Type 2 Diabetes Rx C N X
Generic name:
empagliflozin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Trijardy XR Rate Add review Rx N X
Generic name:
empagliflozin / linagliptin / metformin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zituvimet Rate Add review Rx B N X
Generic name:
metformin / sitagliptin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Zituvimet XR Rate Add review Rx B N X
Generic name:
metformin / sitagliptin systemic
Drug class:
antidiabetic combinations
For consumers:
dosage, interactions, side effects

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Frequently asked questions

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Alternative treatments for Type 2 Diabetes

The following products are considered to be alternative treatments or natural remedies for Type 2 Diabetes. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However, there may be historical, cultural or anecdotal evidence linking their use to the treatment of Type 2 Diabetes.

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.