Metformin/pioglitazone Interactions
There are 464 drugs known to interact with metformin/pioglitazone, along with 14 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 32 are major, 420 are moderate, and 12 are minor.
- View all 464 medications that may interact with metformin/pioglitazone
- View metformin/pioglitazone alcohol/food interactions (4)
- View metformin/pioglitazone disease interactions (14)
Most frequently checked interactions
View interaction reports for metformin / pioglitazone and the medicines listed below.
- Actos (pioglitazone)
- Advair Diskus (fluticasone / salmeterol)
- Aspirin Low Strength (aspirin)
- Ativan (lorazepam)
- Calcium 600 D (calcium / vitamin d)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Farxiga (dapagliflozin)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Januvia (sitagliptin)
- Jardiance (empagliflozin)
- Lantus (insulin glargine)
- Lantus SoloStar (insulin glargine)
- Levemir (insulin detemir)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Nexium (esomeprazole)
- Plavix (clopidogrel)
- Synthroid (levothyroxine)
- Trulicity (dulaglutide)
- Victoza (liraglutide)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Metformin/pioglitazone alcohol/food interactions
There are 4 alcohol/food interactions with metformin / pioglitazone.
Metformin/pioglitazone disease interactions
There are 14 disease interactions with metformin / pioglitazone which include:
- lactic acidosis
- liver disease
- renal dysfunction
- CHF
- type I diabetes
- hypoglycemia
- B12 deficiency
- bladder cancer
- edema
- liver disease
- macular edema
- premenopausal anovulation
- weight gain
- anemia
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More about metformin / pioglitazone
- metformin/pioglitazone consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (5)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: antidiabetic combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
