Empagliflozin / metformin for Type 2 Diabetes User Reviews

• Kis...
• Taken for 6 months to 1 year
• September 19, 2019

"40-year-old female. After being diagnosed with Type 2 Diabetes, I made some serious changes. Before starting the Metformin, I fasted for 5 days, which helped reduce my glucose tremendously. After, I followed/continued with exercise and watching what I ate, I saw some amazing results. After about 1 month of being on Metformin, my A1C went from 14 to 9. My doctor reduced the Metformin dosage and started me on the combination pill Synjardy. After about 2 more months, my A1C dropped to 6.5. So far, it has worked great, and I have maintained below a 7.0 A1C now for approximately a year. I have also lost weight with the medication. I had no negative side effects for the past year until now. For the past few months, I’ve continued to get yeast infections. It gets treated, and it comes back every month after my menstrual cycle. I am making the decision to stop taking Synjardy and start another medication. Loved it before this uncontrollable side effect."

• Car...
• Taken for 6 months to 1 year
• October 4, 2016

"Update to my other review. The doctor's office was able to get things straightened out, and I was able to get Synjardy for free with the discount card after all. I have been on it for about 9 months now. I have lost around 30 lbs, my A1C went from 11.5 at diagnosis to 6.2 at my last doctor's visit and could probably be better if I didn't forget my afternoon dosage all the time. Average fasting blood sugar went from the 280s to the 110s. I wish I could stay on this forever as it has worked great for me, but I'm sure the discount card program will end at some point. Have noticed increased urination, but nothing too terrible. My dosage is the 5 mg-500 mg pill twice a day."

• K2u...
• Taken for 6 months to 1 year
• May 4, 2019

"I've used Synjardy for 8 months. Thankfully, my insurance covers it, and with the savers coupon, I have zero out-of-pocket expense, which is awesome. So you might be wondering, does Synjardy cause weight loss? Yes, it certainly has helped me lose weight, as it suppresses my appetite. I do pee more and am thirsty. I do take vitamin B12, as it's helped with energy and a couple other side effects. Also, the Synjardy has made my A1C go down from 11.8 to 4.9 within 6 months. Every so often, I have tummy issues but have never thrown up from it. All in all, it's done wonders."

• Gar...
• Taken for 1 to 6 months
• April 24, 2023

"Throughout 2022, my A1C's are in the 7's, and my blood pressure (BP) was great, 107/76 in June and 108/78 in Sept. Day-to-day blood sugar readings were 5-7 with lots of walking, and light weights nightly, and proper diet, and my weight is stable. The doctor decided to add Synjardy and reduce Diamicron by 50% in late October. The next A1C in Dec. was 8.3 with a BP of 135/84. Day-to-day blood sugar readings (B/S) are way high, 10-13. I requested taking Diamicron. The doctor worried about low blood sugar and did not comply. My next A1C was 8.3 in March, but my BP was 154/84. The doctor suggested I check my B/P weekly at a local pharmacy. One week later, 196/106 B/P. Ten more checks all around 180/95. Totally out of whack, as were day-to-day B/S. Still, I walk miles every week and have no diet changes. I see the doctor again in 3 days. The only difference in my life is the addition of Synjardy and the reduction of Diamicron. I've stopped weights. Day-to-day B/S is impossible to get on track. Something is out of whack! I am 66 years old and was great till the last six months."

• Car...
• February 29, 2016

"I received a sample of Synjardy and have only been taking it for 4 days. I started off taking 850 mg of Metformin twice a day and 5 mg of Glipizide twice a day. I had good numbers on this, but the Glipizide was causing too many hypo episodes, so my Dr. gave me a sample of Synjardy. The Synjardy has made my numbers more consistently 80-105, and I no longer have any hypo events. I have also lost 4 pounds in 4 days. The only negative I have noticed is having to drink and pee more. It has made me more prone to waking up a little earlier to hit the bathroom, but it hasn't been that bad. They have a savings card, but my insurance will not cover it at all, so I can't use the card, and without that, it is $431 a month, which I cannot afford."

• Spa...
• November 29, 2018

"Since I have been taking Synjardy for the past six days, I have been throwing up with uncontrollable bowels. I have never experienced this kind of side effect from not even plain old metformin. I thought I was literally dying from all the throwing up. I will never take this medication again, ever."

• Peo...
• Taken for less than 1 month
• February 8, 2021

"It's unreal how quickly and drastically my fasting blood glucose dropped. Within 1-2 days, it dropped approximately 100 points, and I was thrilled! Now I should be able to stay off insulin for a while. (Whew!) I was already on 2000 mg of Metformin ER and Glimepiride. I tried using Farxiga, and I don't think it made a significant difference. But man! This Synjardy! Try it if you can. The only side effect for me was it may have made me thirstier than usual. No big deal."

• Rub...
• Taken for less than 1 month
• December 1, 2016

"I've been on it for a week now. Since switching from Metformin, I've noticed no more aches and pains and have been able to work out since the 2nd day of change! Love this Synjardy so far. Using samples, so have no idea on price and insurance, but I'll deal with that when it comes to it."

• Lbs...
• Taken for 1 to 6 months
• June 15, 2018

"I love this drug! I have lost 17 pounds in 11 weeks, and I feel great. No low blood sugar episodes anymore, and no stomach issues like when just taking Metformin. I do have to pee a lot more due to increased thirst, but it’s manageable. I am using samples because my insurance won’t cover any diabetes care (short-term plan with denied pre-existing condition coverage), so I’m worried about what I will do when my doctor can no longer give me samples. Starting A1C before Synjardy on Met/glyburide was 8.8. Now I’m below 6, and it’s only been 3 months. Waking numbers used to be 160-190, now they are an average of 118-120. No side effects for me. Weight loss for me comes from feeling like I have eaten a ton of food when I really haven’t. I push my plate away earlier too. I’m very active though and do intense cardio/training classes, so maybe the combination of feeling better and medicine has kicked my metabolism into full speed. Lol."

• Maz...
• Taken for 6 months to 1 year
• July 25, 2019

"This drug is magical! Lowered my A1C from 11.8 to 5.4 in 3 months. For 6 months, I was on 1000 mg/12.5 mg twice daily. My doctor has now decreased it to once daily. I dropped about 22 kg in 6 months. I suffered from tolerable side effects such as upset stomach and hypotension. I don’t feel thirsty, and urination frequency is normal. Made me hate red meat :)"

• Car...
• Taken for 1 to 6 months
• May 8, 2019

"I've been on Synjardy for about 3 months. Sugar levels are more consistent. No more sugar crashes, and I've lost 13 lbs. No other side effects. It's working great for me! Dr. gave me a coupon so I get it free for 12 months."

• TAa...
• Taken for 1 to 6 months
• August 18, 2019

"After one month, this medicine, Synjardy, brought my A1C down from 8.3 to 7.1. My glucose from 288 to 116. The only problem is that it is giving me a vaginal yeast infection, and it is severe. It goes away a week with meds and comes right back, so I will have to stop. Also, a little nausea. I was getting good results."

• Big...
• Taken for 1 to 6 months
• January 14, 2020

"Dr. put me on Synjardy, and after 3 months, with no change in diet, my A1C went from 5.7 to 8.9!! For the money, you would think it would be a miracle drug. I think I will stick with the cheaper metformin that maintained a 5.7 A1C."

• SRa...
• Taken for 1 to 6 months
• October 17, 2020

"My doc prescribed Synjardy with 12.5 mg/500 mg Metformin twice a day. My daily numbers dropped from 145 to 120 in the last 2 months. Also, my weight reduced by 10 lbs (7% of my total weight). But my blood pressure dropped to 100/60. Earlier it was 117/75. Starting to feel dizzy. Planning to talk to my doc about low BP."

• luv...
• Taken for 2 to 5 years
• April 27, 2019

"I have been using Synjardy for the past 3 years and have found it is better than straight Metformin. I could not leave the house when I was taking 2 - 1,000 mg tablets of Metformin. I am taking the 12.5/1,000 mg tablet 2 times a day, and I am having no problems with it. It has lowered my morning glucose readings closer to 100, and my after-meal readings under 180, which is what I needed. Seems like the mix of the two drugs works better than Metformin alone."

• Fix...
• Taken for 1 to 6 months
• March 9, 2020

"I was on metformin 1000 mg 2 times a day, and that was able to manage my A1c to between 5.8 and 6.2. I then had a cardiac event, 90% LAD blockage, and a subsequent stent. Then I was placed on Synjardy. I have lost 8 lbs in 8 weeks without any real effort, and BG control is really good. Haven't had a new A1c yet. No real side effects. The first workday I felt I had a low BG. I didn't have my meter, however, I had some oatmeal with brown sugar and felt fine in about 20 minutes. I have my meter with me at work now, and BG will get to low 80's, high 70's before lunch... Nothing wrong with that."

• Mad...
• November 20, 2020

"Third day taking this Synjardy XR, I was feeling short of breath, dizzy, pain in belly. Doctor said to skip the evening dose. The next morning, I couldn't stop vomiting. Blood sugar was in the 110s, rose to 180s. My feet, hands, and lips turned purple. In the ER, the triage nurse, upon hearing the medication I'd recently started, yelled out to get me on the list for an ICU room. (During Covid-19 pandemic) I was hospitalized for 5 days. ER doctor stated I was the 3rd patient that week who went in to Euglycemic Ketoacidosis who was on SYNJARDY XR! He says prior to this medication, DKA was usually seen in patients with blood sugars in the 600s, not 100s. My body chemistry was 'not compatible with life.' I've had three doctors state it was 100% the medication that caused me to almost lose my life. Now I'm in physical therapy. Unable to work. Wish I had gotten a 2nd opinion before starting this medication! It turned my life upside down. Prior to this, HbA1c was 6.9."

• Jul...
• Taken for less than 1 month
• June 24, 2018

"Been on Synjardy XR for 1 week and 2 days. The first week, I was told to take 1 tab a day for 7 days, and yesterday was the 1st time I increased to taking 2 pills per day. My A1C is a little over 8, and the doctor is trying to get it down to at least 6. Samples given along with a prescription card. The doctor said it would lower the cost. My insurance doesn't cover Synjardy XR, and it costs $500 a month. A few days later, I remembered about the card my doctor gave me. I called the pharmacy with card info, and it went through. Costing me now $20 a month, and the card is good for 1 year. On the first week, really no side effects, I maintained the same weight all week. When I had to take 2 pills a day, that's a different story. I better stay close to the bathroom until my body adjusts. Aside from being thirsty and having to urinate a lot, I have felt a few lows to the point where I get dizzy. Magnesium helps dizziness. I advise anyone who can't afford the prescription to go to the website and see if you can get 1 of those prescription cards from their site."

• Hom...
• Taken for 1 to 6 months
• April 19, 2020

"It really helped me lower my sugar, but it gave me difficulty breathing, and because of that, I also couldn't sleep well. I wish Synjardy didn't have such side effects on me, cause it really works. But with strict diet and exercise, I have been able to keep my sugar in the normal range."

• bel...
• Taken for less than 1 month
• August 24, 2022

"I am 47 years old, on an insulin pump, and have had pancreatitis 4 times in my life due to high triglycerides. I am currently taking Ozempic at the lowest dose because I am afraid of pancreatitis revisiting (worst pain ever). Last week, my doctor put me on the Synjardy, and my sugars this last week have been under 150 even after eating. I will say that I do watch my carb intake, keeping it under 30 per meal, and I lost 4.2 pounds this week. I don’t know if these results are normal, but currently, I am a believer. I cannot wait to see down the road if I have continued success. I have had frequent headaches, but I am hoping those pass. Hope this helps someone."

• Gra...
• Taken for less than 1 month
• January 5, 2022

"After being on Metformin ER for a number of years and my numbers creeping up, my doctor suggested Synjardy XR. I agreed to try it but was very apprehensive, esp., after reading about the serious side effects. Fatal gangrene of the genitals and perineum, anyone? OMG, could anything be worse? My doctor assured me those side effects were quite rare. After only 2 weeks, I ended up with a serious UTI. No way, no how, and no thanks! Tossed them straight in the bin!"

• KCa...
• Taken for less than 1 month
• September 9, 2020

"I was taking a dose of 2000 mg of Metformin a day for several years. About 6 months ago, my A1C went from 6.7 to 9. I was having severe fatigue and constant stomach pain and diarrhea. After extensive blood and stool tests were negative, my doctor added Synjardy XR 12.5/1000 once a day. Four days later, I was rushed to the hospital with severe dehydration and ketoacidosis from diarrhea and vomiting. I have never been so sick in my life! After two days and nights of fluid in the hospital, I came home and threw those samples away. I did lose 20 lbs, though."

• Twi...
• Taken for 2 to 5 years
• July 20, 2021

"This medication has really controlled my blood sugar dramatically compared to Metformin alone. My HbA1c levels are at 6.8 currently. I have had a few yeast infections over the couple of years that I've been on Synjardy. But miconazole ovules seem to take care of it. Much happier being on Synjardy compared to before."

• Jay...
• Taken for 1 to 6 months
• April 30, 2022

"So far, it has been amazing in helping reduce blood sugar levels. For me, no side effects (maybe a little more tired throughout the days, perhaps a B12 vitamin could help). Been on this new med from just metformin for 2 months now and down 15+ lbs too. Hope I get to where I'm off meds altogether and maintain things..."

• Ron...
• Taken for less than 1 month
• September 12, 2021

"Been taking this medicine for five days, can’t sleep, have heart palpitations, nauseous, dizzy, and I respect other people who are successful. It just doesn’t work for me at all. I’m going back to Metformin, will exercise better. I think this stuff is awful, and it was $500."