Skip to main content

Medications for Colorectal Cancer

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
oxaliplatin 4.8 4 reviews for oxaliplatin to treat Colorectal Cancer Rx D N
Generic name:
oxaliplatin systemic
Brand name:
Eloxatin
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Xeloda 8.5 11 reviews for Xeloda to treat Colorectal Cancer Rx D N
Generic name:
capecitabine systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
capecitabine 8.2 21 reviews for capecitabine to treat Colorectal Cancer Rx D N
Generic name:
capecitabine systemic
Brand name:
Xeloda
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
fluorouracil 2.7 3 reviews for fluorouracil to treat Colorectal Cancer Rx D N
Generic name:
fluorouracil systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Avastin 7.0 3 reviews for Avastin to treat Colorectal Cancer Rx C N
Generic name:
bevacizumab systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
leucovorin Rate Add review Rx C N
Generic name:
leucovorin systemic
Drug class:
antidotes
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Keytruda 7.4 8 reviews for Keytruda to treat Colorectal Cancer Rx D N
Generic name:
pembrolizumab systemic
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Betaseron Rate Add review Rx C N X
Generic name:
interferon beta-1b systemic
Drug class:
interferons
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Opdivo 6.7 7 reviews for Opdivo to treat Colorectal Cancer Rx N
Generic name:
nivolumab systemic
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
nivolumab 6.7 7 reviews for nivolumab to treat Colorectal Cancer Rx N
Generic name:
nivolumab systemic
Brand name:
Opdivo
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
pembrolizumab 7.5 11 reviews for pembrolizumab to treat Colorectal Cancer Rx D N
Generic name:
pembrolizumab systemic
Brand name:
Keytruda
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Yervoy Rate Add review Rx C N
Generic name:
ipilimumab systemic
Drug class:
anti-CTLA-4 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
interferon beta-1b Rate Add review Rx C N X
Generic name:
interferon beta-1b systemic
Brand name:
Betaseron
Drug class:
interferons
For consumers:
dosage, interactions, side effects
ipilimumab Rate Add review Rx C N
Generic name:
ipilimumab systemic
Brand name:
Yervoy
Drug class:
anti-CTLA-4 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
hyaluronidase / nivolumab Rate Add review Rx N
Generic name:
hyaluronidase / nivolumab systemic
Brand name:
Opdivo Qvantig
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
Lumakras Rate Add review Rx N
Generic name:
sotorasib systemic
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Opdivo Qvantig Rate Add review Rx N
Generic name:
hyaluronidase / nivolumab systemic
Drug class:
anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors)
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
sotorasib Rate Add review Rx N
Generic name:
sotorasib systemic
Brand name:
Lumakras
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
irinotecan 2.3 3 reviews for irinotecan to treat Colorectal Cancer Rx D N
Generic name:
irinotecan systemic
Brand name:
Camptosar
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Stivarga 3.6 8 reviews for Stivarga to treat Colorectal Cancer Rx D N
Generic name:
regorafenib systemic
Drug class:
multikinase inhibitors, VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
bevacizumab 7.0 3 reviews for bevacizumab to treat Colorectal Cancer Rx C N
Generic name:
bevacizumab systemic
Brand names:
Avastin, Mvasi, Zirabev, Alymsys, Vegzelma, Avzivi, Jobevne
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Erbitux 7.8 4 reviews for Erbitux to treat Colorectal Cancer Rx C N
Generic name:
cetuximab systemic
Drug class:
EGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lonsurf Rate Add review Rx N
Generic name:
tipiracil / trifluridine systemic
Drug class:
antineoplastic combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vectibix 7.0 4 reviews for Vectibix to treat Colorectal Cancer Rx C N
Generic name:
panitumumab systemic
Drug class:
EGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cetuximab 7.8 4 reviews for cetuximab to treat Colorectal Cancer Rx C N
Generic name:
cetuximab systemic
Brand name:
Erbitux
Drug class:
EGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Camptosar 5.0 1 review for Camptosar to treat Colorectal Cancer Rx D N
Generic name:
irinotecan systemic
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Eloxatin Rate Add review Rx D N
Generic name:
oxaliplatin systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
methotrexate Off-label Rate Add review Rx X N X
Generic name:
methotrexate systemic
Drug class:
antimetabolites, antirheumatics, antipsoriatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
Zaltrap 10 1 review for Zaltrap to treat Colorectal Cancer Rx C N
Generic name:
ziv-aflibercept systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
panitumumab 5.7 7 reviews for panitumumab to treat Colorectal Cancer Rx C N
Generic name:
panitumumab systemic
Brand name:
Vectibix
Drug class:
EGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
regorafenib 3.3 9 reviews for regorafenib to treat Colorectal Cancer Rx D N
Generic name:
regorafenib systemic
Brand name:
Stivarga
Drug class:
multikinase inhibitors, VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Fusilev Rate Add review Rx C N
Generic name:
levoleucovorin systemic
Drug class:
antidotes
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Mvasi Rate Add review Rx C N
Generic name:
bevacizumab systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Braftovi 1.0 1 review for Braftovi to treat Colorectal Cancer Rx N
Generic name:
encorafenib systemic
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Cyramza Rate Add review Rx C N
Generic name:
ramucirumab systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ramucirumab Rate Add review Rx C N
Generic name:
ramucirumab systemic
Brand name:
Cyramza
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Zirabev Rate Add review Rx C N
Generic name:
bevacizumab systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ziv-aflibercept 10 1 review for ziv-aflibercept to treat Colorectal Cancer Rx C N
Generic name:
ziv-aflibercept systemic
Brand name:
Zaltrap
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Alymsys Rate Add review Rx C N
Generic name:
bevacizumab systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
encorafenib 1.0 1 review for encorafenib to treat Colorectal Cancer Rx N
Generic name:
encorafenib systemic
Brand name:
Braftovi
Drug class:
multikinase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
fruquintinib Rate Add review Rx N
Generic name:
fruquintinib systemic
Brand name:
Fruzaqla
Drug class:
multikinase inhibitors, VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Khapzory Rate Add review Rx C N
Generic name:
levoleucovorin systemic
Drug class:
antidotes
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
levoleucovorin Rate Add review Rx C N
Generic name:
levoleucovorin systemic
Brand names:
Fusilev, Khapzory
Drug class:
antidotes
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
tipiracil / trifluridine Rate Add review Rx N
Generic name:
tipiracil / trifluridine systemic
Brand name:
Lonsurf
Drug class:
antineoplastic combinations
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Tukysa Rate Add review Rx N
Generic name:
tucatinib systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vegzelma Rate Add review Rx C N
Generic name:
bevacizumab systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
adagrasib Rate Add review Rx N
Generic name:
adagrasib systemic
Brand name:
Krazati
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Avzivi Rate Add review Rx C N
Generic name:
bevacizumab systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Fruzaqla Rate Add review Rx N
Generic name:
fruquintinib systemic
Drug class:
multikinase inhibitors, VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Jobevne Rate Add review Rx C N
Generic name:
bevacizumab systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Keytruda Qlex Rate Add review Rx U
Generic name:
berahyaluronidase alfa / pembrolizumab systemic
For consumers:
Krazati Rate Add review Rx N
Generic name:
adagrasib systemic
Drug class:
miscellaneous antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tucatinib Rate Add review Rx N
Generic name:
tucatinib systemic
Brand name:
Tukysa
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph

Viewing all results. Return to paging

Frequently asked questions

View more FAQ

Topics under Colorectal Cancer

Learn more about Colorectal Cancer

Care guides

Symptoms and treatments

Medicine.com guides (external)

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer