Generic Name: levoleucovorin (LEE voe LOO koe voe rin)
Brand Name: Khapzory
What is Khapzory?
Khapzory is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer.
Khapzory is also used to treat or prevent toxic effects of methotrexate in people whose bodies do not eliminate methotrexate properly after the drug is metabolized. This medicine may also be used to treat toxic effects of an overdose or methotrexate or certain other medications.
Khapzory should not be used to treat anemia that is caused by a lack of vitamin B12.
Khapzory may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not be treated with Khapzory if you are allergic to Khapzory, folic acid, or folinic acid.
If possible, before you receive Khapzory, tell your doctor or caregivers if you have:
kidney disease; or
if you are dehydrated.
Tell your doctor if you are pregnant or breastfeeding.
How is Khapzory given?
Khapzory is given as an infusion into a vein. A healthcare provider will give you this injection.
For use with methotrexate, Khapzory is usually given every 3 to 6 hours.
For colorectal cancer, Khapzory is usually given daily as a 5-day treatment, repeated every 4 to 5 weeks.
After treatment with Khapzory, you will be watched to make sure this medicine has been effective.
You will need frequent medical tests to help your doctor determine how long to treat you with Khapzory.
What happens if I miss a dose?
If Khapzory is given by a healthcare professional in an clinical setting, you are not likely to miss a dose.
If you are receiving Khapzory daily in 4-week treatment cycles, call your doctor for instructions if you miss an appointment for your scheduled injection.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while receiving Khapzory?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Khapzory side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your doctor or caregivers at once if you have:
blisters or ulcers in your mouth, red or swollen gums, trouble swallowing;
severe or ongoing diarrhea;
a light-headed feeling, like you might pass out;
kidney problems--little or no urination; painful or difficult urination; swelling in your feet or ankles.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Khapzory?
Tell your doctor about all your other medicines, especially:
a multivitamin or mineral supplement than contains folic acid; or
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2021 Cerner Multum, Inc. Version: 6.01.
More about Khapzory (levoleucovorin)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: antidotes
- FDA Alerts (1)
- FDA Approval History
Other brands: Fusilev