Irinotecan Interactions
There are 443 drugs known to interact with irinotecan, along with 4 disease interactions. Of the total drug interactions, 93 are major, 323 are moderate, and 27 are minor.
- View all 443 medications that may interact with irinotecan
- View irinotecan disease interactions (4)
Most frequently checked interactions
View interaction reports for irinotecan and the medicines listed below.
- Activated Charcoal (charcoal)
- Aloxi (palonosetron)
- Ativan (lorazepam)
- Avastin (bevacizumab)
- Benadryl (diphenhydramine)
- Compazine (prochlorperazine)
- Creon (pancrelipase)
- Decadron (dexamethasone)
- Dilaudid (hydromorphone)
- Eliquis (apixaban)
- Fentanyl Transdermal System (fentanyl)
- Imodium (loperamide)
- Lipitor (atorvastatin)
- Lomotil (atropine / diphenoxylate)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Neulasta (pegfilgrastim)
- Neupogen (filgrastim)
- Norco (acetaminophen / hydrocodone)
- Paracetamol (acetaminophen)
- Pepcid (famotidine)
- Tylenol (acetaminophen)
- Vectibix (panitumumab)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin K2 (menaquinone)
- Xeloda (capecitabine)
- Zofran (ondansetron)
Irinotecan disease interactions
There are 4 disease interactions with irinotecan which include:
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More about irinotecan
- irinotecan consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (3)
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous antineoplastics
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.