Irinotecan Interactions
There are 418 drugs known to interact with irinotecan, along with 4 disease interactions. Of the total drug interactions, 89 are major, 302 are moderate, and 27 are minor.
- View all 418 medications that may interact with irinotecan
- View irinotecan disease interactions (4)
Most frequently checked interactions
View interaction reports for irinotecan and the medicines listed below.
- Ativan (lorazepam)
- Ativan (lorazepam)
- Avastin (bevacizumab)
- Avastin (bevacizumab)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Compazine (prochlorperazine)
- Compazine (prochlorperazine)
- Creon (pancrelipase)
- Creon (pancrelipase)
- Decadron (dexamethasone)
- Decadron (dexamethasone)
- Dilaudid (hydromorphone)
- Dilaudid (hydromorphone)
- Fentanyl Transdermal System (fentanyl)
- Fentanyl Transdermal System (fentanyl)
- Imodium (loperamide)
- Imodium (loperamide)
- Lomotil (atropine / diphenoxylate)
- Lomotil (atropine / diphenoxylate)
- MiraLAX (polyethylene glycol 3350)
- MiraLAX (polyethylene glycol 3350)
- Paracetamol (acetaminophen)
- Paracetamol (acetaminophen)
- Vectibix (panitumumab)
- Vectibix (panitumumab)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zofran (ondansetron)
- Zofran (ondansetron)
Irinotecan disease interactions
There are 4 disease interactions with irinotecan which include:
More about irinotecan
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- During pregnancy
- Drug class: miscellaneous antineoplastics
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.