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Medications for Osteoporosis

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
alendronate 3.0 125 reviews for alendronate to treat Osteoporosis Rx C N
Generic name:
alendronate systemic
Brand names:
Fosamax, Binosto
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
calcium / vitamin d 8.2 5 reviews for calcium / vitamin d to treat Osteoporosis OTC C N
Generic name:
calcium / vitamin d systemic
Brand names:
Os-Cal Calcium+D3, Calcitrate with D, Os-Cal 500 Chewable
Drug class:
vitamin and mineral combinations
For consumers:
dosage, interactions, side effects
Prolia 2.9 372 reviews for Prolia to treat Osteoporosis Rx X N
Generic name:
denosumab systemic
Drug class:
miscellaneous bone resorption inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Fosamax 2.8 61 reviews for Fosamax to treat Osteoporosis Rx C N
Generic name:
alendronate systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Forteo 5.3 157 reviews for Forteo to treat Osteoporosis Rx C N
Generic name:
teriparatide systemic
Drug class:
parathyroid hormone and analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
teriparatide 5.3 164 reviews for teriparatide to treat Osteoporosis Rx C N
Generic name:
teriparatide systemic
Brand name:
Forteo
Drug class:
parathyroid hormone and analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Evenity 6.6 76 reviews for Evenity to treat Osteoporosis Rx N
Generic name:
romosozumab systemic
Drug class:
miscellaneous bone resorption inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tymlos 5.0 107 reviews for Tymlos to treat Osteoporosis Rx N
Generic name:
abaloparatide systemic
Drug class:
parathyroid hormone and analogs
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
calcium carbonate 4.0 1 review for calcium carbonate to treat Osteoporosis OTC N N
Generic name:
calcium carbonate systemic
Brand names:
Caltrate, Calcium Oyster Shell, Cal-Gest, Oyster Cal, Oyster Calcium, Oyster Shell, Oyster Shell Calcium 500
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
romosozumab 6.7 81 reviews for romosozumab to treat Osteoporosis Rx N
Generic name:
romosozumab systemic
Brand name:
Evenity
Drug class:
miscellaneous bone resorption inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
abaloparatide 4.9 110 reviews for abaloparatide to treat Osteoporosis Rx N
Generic name:
abaloparatide systemic
Brand name:
Tymlos
Drug class:
parathyroid hormone and analogs
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Boniva 3.4 80 reviews for Boniva to treat Osteoporosis Rx C N
Generic name:
ibandronate systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Actonel 3.0 21 reviews for Actonel to treat Osteoporosis Rx C N
Generic name:
risedronate systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Reclast 5.3 215 reviews for Reclast to treat Osteoporosis Rx D N
Generic name:
zoledronic acid systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Evista 7.4 8 reviews for Evista to treat Osteoporosis Rx X N
Generic name:
raloxifene systemic
Drug class:
hormones/antineoplastics, selective estrogen receptor modulators
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
calcium citrate Rate Add review Rx/OTC C N
Generic name:
calcium citrate systemic
Drug class:
minerals and electrolytes
For consumers:
interactions, side effects
risedronate 2.8 63 reviews for risedronate to treat Osteoporosis Rx C N
Generic name:
risedronate systemic
Brand names:
Actonel, Atelvia
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
raloxifene 5.7 12 reviews for raloxifene to treat Osteoporosis Rx X N
Generic name:
raloxifene systemic
Brand name:
Evista
Drug class:
hormones/antineoplastics, selective estrogen receptor modulators
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Caltrate Rate Add review OTC N N
Generic name:
calcium carbonate systemic
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
denosumab 2.9 380 reviews for denosumab to treat Osteoporosis Rx X N
Generic name:
denosumab systemic
Brand names:
Prolia, Jubbonti
Drug class:
miscellaneous bone resorption inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ibandronate 3.2 96 reviews for ibandronate to treat Osteoporosis Rx C N
Generic name:
ibandronate systemic
Brand name:
Boniva
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Premarin 10 5 reviews for Premarin to treat Osteoporosis Rx X N
Generic name:
conjugated estrogens systemic
Drug class:
estrogens
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Atelvia 4.7 3 reviews for Atelvia to treat Osteoporosis Rx C N
Generic name:
risedronate systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
calcitonin 5.5 11 reviews for calcitonin to treat Osteoporosis Rx C N
Generic name:
calcitonin systemic
Brand name:
Miacalcin
Drug class:
calcitonin
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Zometa 3.6 13 reviews for Zometa to treat Osteoporosis Rx D N
Generic name:
zoledronic acid systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Binosto Rate Add review Rx C N
Generic name:
alendronate systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
zoledronic acid 5.1 297 reviews for zoledronic acid to treat Osteoporosis Rx D N
Generic name:
zoledronic acid systemic
Brand names:
Reclast, Zometa, Aclasta
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
alendronate / cholecalciferol Rate Add review Rx C N
Generic name:
alendronate / cholecalciferol systemic
Brand name:
Fosamax Plus D
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
Fosamax Plus D Rate Add review Rx C N
Generic name:
alendronate / cholecalciferol systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Calcium Oyster Shell Rate Add review OTC N N
Generic name:
calcium carbonate systemic
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
Os-Cal Calcium+D3 7.0 1 review for Os-Cal Calcium+D3 to treat Osteoporosis OTC C N
Generic name:
calcium / vitamin d systemic
For consumers:
dosage, interactions, side effects
Aclasta 4.3 29 reviews for Aclasta to treat Osteoporosis Rx D N
Generic name:
zoledronic acid systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
Cal-Gest Rate Add review OTC N N
Generic name:
calcium carbonate systemic
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
Calcitrate with D Rate Add review OTC C N
Generic name:
calcium / vitamin d systemic
Drug class:
vitamin and mineral combinations
For consumers:
dosage, interactions, side effects
conjugated estrogens 10 6 reviews for conjugated estrogens to treat Osteoporosis Rx X N
Generic name:
conjugated estrogens systemic
Brand names:
Premarin, Premarin Intravenous
Drug class:
estrogens
For consumers:
dosage, interactions, side effects
Miacalcin 1.0 1 review for Miacalcin to treat Osteoporosis Rx C N
Generic name:
calcitonin systemic
Drug class:
calcitonin
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Oyster Cal Rate Add review OTC N N
Generic name:
calcium carbonate systemic
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
Oyster Calcium Rate Add review OTC N N
Generic name:
calcium carbonate systemic
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
Oyster Shell Rate Add review OTC N N
Generic name:
calcium carbonate systemic
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
Oyster Shell Calcium 500 Rate Add review OTC N N
Generic name:
calcium carbonate systemic
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
Prempro 9.0 1 review for Prempro to treat Osteoporosis Rx X N
Generic name:
conjugated estrogens / medroxyprogesterone systemic
Drug class:
sex hormone combinations
For consumers:
dosage, interactions, side effects
calcium gluconate Rate Add review Rx/OTC C N
Generic name:
calcium gluconate systemic
Drug class:
minerals and electrolytes
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
calcium lactate Rate Add review Rx/OTC C N
Generic name:
calcium lactate systemic
Drug class:
minerals and electrolytes
For consumers:
dosage, interactions, side effects
calcium phosphate, tribasic Rate Add review OTC N N
Generic name:
calcium phosphate, tribasic systemic
Brand name:
Posture
Drug class:
minerals and electrolytes
For consumers:
dosage, interactions, side effects
Jubbonti Rate Add review Rx X N
Generic name:
denosumab systemic
Drug class:
miscellaneous bone resorption inhibitors
For consumers:
dosage, interactions, side effects
Os-Cal 500 Chewable Rate Add review OTC C N
Generic name:
calcium / vitamin d systemic
For consumers:
dosage, interactions, side effects
bazedoxifene / conjugated estrogens 5.5 2 reviews for bazedoxifene / conjugated estrogens to treat Osteoporosis Rx X N
Generic name:
bazedoxifene / conjugated estrogens systemic
Brand name:
Duavee
Drug class:
sex hormone combinations
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
conjugated estrogens / medroxyprogesterone 9.0 1 review for conjugated estrogens / medroxyprogesterone to treat Osteoporosis Rx X N
Generic name:
conjugated estrogens / medroxyprogesterone systemic
Brand names:
Prempro, Premphase
Drug class:
sex hormone combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Duavee 5.5 2 reviews for Duavee to treat Osteoporosis Rx X N
Generic name:
bazedoxifene / conjugated estrogens systemic
Drug class:
sex hormone combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
esterified estrogens Rate Add review Rx X N
Generic name:
esterified estrogens systemic
Brand name:
Menest
Drug class:
estrogens
For consumers:
dosage, interactions, side effects
estropipate Rate Add review Rx X N
Generic name:
estropipate systemic
Brand name:
Ogen
Drug class:
estrogens
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ethinyl estradiol / norethindrone Off-label Rate Add review Rx X N X
Generic name:
ethinyl estradiol / norethindrone systemic
Drug class:
contraceptives, sex hormone combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Menest Rate Add review Rx X N
Generic name:
esterified estrogens systemic
Drug class:
estrogens
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ogen Rate Add review Rx X N
Generic name:
estropipate systemic
Drug class:
estrogens
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Posture Rate Add review OTC N N
Generic name:
calcium phosphate, tribasic systemic
Drug class:
minerals and electrolytes
For consumers:
dosage, interactions, side effects
Premarin Intravenous Rate Add review Rx X N
Generic name:
conjugated estrogens systemic
Drug class:
estrogens
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Premphase Rate Add review Rx X N
Generic name:
conjugated estrogens / medroxyprogesterone systemic
Drug class:
sex hormone combinations
For consumers:
dosage, interactions, side effects

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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