Premphase Interactions
There are 299 drugs known to interact with Premphase (conjugated estrogens/medroxyprogesterone), along with 25 disease interactions, and 6 alcohol/food interactions. Of the total drug interactions, 40 are major, 238 are moderate, and 21 are minor.
- View all 299 medications that may interact with Premphase
- View Premphase alcohol/food interactions (6)
- View Premphase disease interactions (25)
Most frequently checked interactions
View interaction reports for Premphase (conjugated estrogens / medroxyprogesterone) and the medicines listed below.
- Allegra (fexofenadine)
- Allegra-D 24 Hour (fexofenadine / pseudoephedrine)
- Amaryl (glimepiride)
- amitriptyline
- Amoxil (amoxicillin)
- Atrovent (ipratropium)
- Augmentin (amoxicillin / clavulanate)
- buspirone
- Cardizem (diltiazem)
- Celebrex (celecoxib)
- Celexa (citalopram)
- Cipro (ciprofloxacin)
- Combivent (albuterol / ipratropium)
- Coreg (carvedilol)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Depo Provera (medroxyprogesterone)
- Elavil (amitriptyline)
- Estrace (estradiol)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- fluoxetine
- Lipitor (atorvastatin)
- Propecia (finasteride)
- Prozac (fluoxetine)
- Synthroid (levothyroxine)
- trazodone
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Premphase alcohol/food interactions
There are 6 alcohol/food interactions with Premphase (conjugated estrogens / medroxyprogesterone).
Premphase disease interactions
There are 25 disease interactions with Premphase (conjugated estrogens / medroxyprogesterone) which include:
- abnormal genital bleeding
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- bone mineral density
- menstrual bleeding
- breast malignancy
- liver disease
- thromboembolism
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
- hyperlipidemia
- weight gain
Report options
More about Premphase (conjugated estrogens / medroxyprogesterone)
- Premphase consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: sex hormone combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
