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User Reviews for Estradiol Patch

Estradiol Patch has an average rating of 4.0 out of 10 from a total of 137 ratings on Drugs.com. 28% of reviewers reported a positive experience, while 64% reported a negative experience.

Condition Avg. Rating Reviews Compare
Postmenopausal Symptoms  
4.1
102 reviews 157 medications
Oophorectomy  
3.3
24 reviews 35 medications
Hypoestrogenism  
1.0
5 reviews 37 medications
Primary Ovarian Failure  
6.0
5 reviews 36 medications
Prostate Cancer  
9.0
1 reviews 55 medications
Summary of Estradiol Patch reviews 4.0 137 reviews

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Estradiol Patch

loribean · February 19, 2016

For Postmenopausal Symptoms: “this medication saved my life...I actually like the mylan better than the vivelle as far as the way I feel, the vivelle caused sinus problems and gassy bloat, the mylan product did not for me, however the mylan product doesn't stick as well or last as long....OVERALL: I love estrogen replacement and it is a TRAGEDY that women are suffering and their docs are not offering HRT when it is now proven that HRT prolongs life and has a protective influence on heart, bones and brain. I want to tell every woman out there do not be a hero, do not suffer, and do not be afraid. estrogen is good for you and can give you your life back. why do none of the women I talk to know this? crime!!”

10 / 10
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Khatgirl · Taken for 2 to 5 years · June 7, 2020

For Postmenopausal Symptoms: “I've been using these patches for several years now. They work much better than the pills did. Once in a great while I would have one unstick a day or 2 early, so I would just replace it with the next one in the box. But due to the pandemic, I got a 3 month supply, and they are drastically not sticking (even after 4 days), and I am short 2 weeks before my insurance is willing to refill my script again. And my last one completely fell off this morning! Mylan needs to get a better adhesive for these. (I would give the drug a 10 rating if it stayed on)”

7 / 10
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Donna · Taken for less than 1 month · August 5, 2020

For Postmenopausal Symptoms: “The Sandoz brand estradiol patch is absolute garbage. It stops working for me after about 6-8 hours, and it's supposed to last 7 days. My gyn told me to prep skin with acetone ( !!! ) and to dry skin with hair dryer then apply patch and hold 10 seconds. Women deserve better than this rubbish - in all forms, from having to apply acetone to skin, to patches that don't live up to what they're supposed to do.”

1 / 10
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Rosie B · Taken for 1 to 6 months · January 3, 2021

For Primary Ovarian Failure: “I’m 60 and had my ovaries removed 11 months ago. So for 5 months I have been using a new bio identical biest estriol & estradiol prescription along with progesterone gel. My hot flashes were bad, my vaginal irritation was unbearable. I Changed to estradiol gel and progesterone gel. My Hot flashes got so severe and vaginal irritation was so unbearable. I Finally decided to try the estradiol 0.075 patch changing 2 times a week. In just 2 days saw incredible improvement in hot flashes, mood energy, motivation, emotional mood. It gave me relief from all my symptoms. The brand I was given is manufactured by Mylan, which was given absolutely horrible low reviews. I was scared it wasn’t going to work for me, but decided to try it anyway because I was so very miserable. Can’t tell you how much relief I am feeling being in the patch and taking the progesterone micronized 100 mg pill. It’s been a lifesaver for me.”

10 / 10
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Anonymous · Taken for less than 1 month · September 9, 2020

For Postmenopausal Symptoms: “Used Sandoz brand for the first 8 estradiol patches. No problem. Pharmacy switched to Mylan, a horrible experience. I use twice a week. After the first 2 days, it starts to itch and turn red. Burning sensation by day 3 and its hard to remove and leaves deep red burn marks and continues to itch for a week. Marks remain on my body for over a month now. Not recommended!”

1 / 10
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Anonymous · Taken for 1 to 6 months · February 23, 2022

For Postmenopausal Symptoms: “I absolutely can't stand the mylan brand estradiol patch. For 3 years I have been using the Sandoz brand and loved it. No issues. In January when I picked my patches up I realized the brand was different..ok no big deal is whatI told my self. A patch is a patch right? Well it makes a difference. The mylan comes off in 2-3 days and I am having to use tegaderm to keep it on. Then the awful rash that is still on my skin after being off for 4 weeks now. I have searched high and low for Sandoz and NO ONE carries anymore. What is a person to do?”

1 / 10
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Donna · Taken for less than 1 month · September 27, 2020

For Postmenopausal Symptoms: “Following up to my August 5, 2020 review of the Sandoz patch. My gyn switched me to a twice weekly patch - Mylan. This brand is worse than Sandoz. I applied a patch Friday night, and by Saturday evening I was sweating profusely. This is the second week on the Mylan patches. Again, women deserve better than being Guinea pigs for cheap drug companies.”

1 / 10
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Tiger · Taken for 2 to 5 years · December 23, 2020

For Postmenopausal Symptoms: “I was put on the minivelle patch several years ago. It worked great. A year ago my pharmacy changed to this estradiol patch made by Mylan. I didn't notice until I used it. The patch does not stay on, but the worst part is what it does to my skin. I have horrid red patches that hurt and itch. And, they do not go away. Now I am having trouble finding a place to place the patch because I am covered in the scars from using this brand. I use CVS pharmacy. they told me they cannot get the patch which is why they switched to Mylan. I am contacting Noven to see what is going on. I see my doctor next month. I cannot continue using this product. It is horrible.”

1 / 10
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Mert · Taken for 10 years or more · January 22, 2020

For Postmenopausal Symptoms: “I’ve used lots of different patches over the years. My favorites have been the Vivelle Dot and the Sandoz patch. The Mylan estradiol patch is worthless - you’re supposed to wear it a week, but it only stays on lasts a day or two, it smells, and it causes skin irritation. Unfortunately, it’s the only one that I know that my insurance will pay for. I’ve been using Sandoz, but have to pay $65 a month for it. Does anybody have a suggestion on a patch estrogen that Priority Health pays for?”

10 / 10
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Hrm2 · Taken for less than 1 month · August 23, 2019

For Postmenopausal Symptoms: “Absolutely AWFUL!! I have been prescribed Estradiol Patches made by Sandoz and I am supposed to keep it on for a week. I maxed out at 6 1/2 HOURS ....they are truly worse than generic cartoon Band-Aids that are overpriced & don't stick! How in the world did these ever pass quality control from the FDA?!?! A total rip-off!! I clean with alcohol, let air dry, used tape and they still come off. ANY amount of perspiration will make them bubble right off. Sorry, but we all perspire EVERY SINGLE DAY! How was that little tidbit overlooked?”

1 / 10
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doodlebuggi · April 19, 2021

For Postmenopausal Symptoms: “Sandoz patch... I don't find it effective AT ALL. If I use the whole patch it's like someone gave me speed for about 4-5 hours it had a super racy heart, super wound up, then.. nothing. The speedy feeling has made me remove the patch. Cut the 0.5 patch in half. Doesn't feel like it's doing anything particularly? WHY DOES THE US NOT SELL ESTRADOT? It is MADE IN THE US! Oh, and what is it with the PERMANENT red marks????? Take a patch off and there's a red mark that is taking weeks and weeks to go way (if it does at all). It's like it's been tattooed to my skin. In 18 months of estradot NEVER had that problem. Never had a sticking problem. Or a tolerance problem, just an acquiring problem - which again, is completely idiotic.. the boxes I got were labeled right on them "made in the USA" but they're SOLD in Australia. Why can't I get a US made medication IN the actual US??????? And why does it cost me a third to buy it elsewhere than any of these US acquirable patches cost?????”

1 / 10
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Anonymous · Taken for 10 years or more · October 5, 2019

“TEGADERM !!! - won’t help with Mylan generic because patch is horrible- worthless. Forever, I’ve had hormonal headaches. No headaches for 10 years while on estrogen patch. Headaches were back almost immediately after applying the junk Mylan patch. Sandoz generic seems to work ok. TRICK!!! I learned as hospital nurse. uses Tegaderm (clear/transparent film patches). Clean skin with alcohol and then rinse with warm water and dry, warm and dry skin slightly with blow dryer. Apply your patch and hold for 10-15 seconds. Then apply tegaderm patch over your estrogen patch. Amazon has all sizes and cheap. So worth it. It keeps your patch secure. My jeans don’t rub it off and swimming or bathtubs no problem. (submerged in hot water/jacuzzi does increase estrogen delivery with patch and it may not last as long - so I’ve been told).”

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Anonymous · Taken for less than 1 month · May 11, 2020

For Postmenopausal Symptoms: “I just started using the Mylan Estradiol patch after using the gel. I wanted to try something more user friendly than the gel though the gel worked well. I have had the same terrible skin reactions to the patch as I’ve seen commented on this site. I called Mylan to file a product complaint and plan to do so with the FDA as well. I will ask my doctor to write for another type of patch.”

3 / 10
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Ruthie · Taken for less than 1 month · June 5, 2020

For Postmenopausal Symptoms: “I used to use Climara. Great option. After I changes insurance I had to use a Mexican brand that worked really well. After I moved to another state I had to get a US brand. I was give Mylan Estradiol patches and after 2 days or less they fall off. I just feel I wasted my money and they are not cheap.”

1 / 10
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CindiLou · Taken for 1 to 2 years · August 19, 2020

For Postmenopausal Symptoms: “Sandoz Estradiol Patch does not stick. It does not peel, instead the entire patch comes loose at once. I get 2 days, maybe 3 days out of a patch. Do not accept Sandoz brand from your pharmacy, you will be wasting your money.”

1 / 10
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Majestic · Taken for 6 months to 1 year · July 30, 2019

For Postmenopausal Symptoms: “I have used the estradiol patch but will probably have to change to something else. I initially did fine and was happy with the patch. However, this PAST month something has changed. The patch areas have become itchy, red, and irritated. I called my healthcare provider...she is also on the same patch and has experienced the same issue this PAST month. Obviously, the Mylan company has changed something...adhesive? Something that isn’t working. I make a call to customer service and they didn’t seem to concerned. Houston...we have a problem. Mylan...fess us to what changes you made and fix it!”

1 / 10
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SusyQ · Taken for 1 to 6 months · May 15, 2020

For Postmenopausal Symptoms: “This patch is so frustrating. It only stays on a couple of days because the material is it made of allows the water to soak in when you shower. Then the skin stays wet underneath and starts smelling sour. The adhesive on the edges irritate my skin and causes itching..What good is it if I can only get about 3 days out if it? I used to use a thinner patch made out of a different material and I never could tell I even had it on, but the company quit producing it.”

8 / 10
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NJ Grandma · Taken for 1 to 6 months · June 12, 2015

For Postmenopausal Symptoms: “This refers to the Mylan estradiol twice weekly patches. After 16 comfortable years using Vivelle Dot estradiol patches, I was supplied by Express Scripts with the new, supposedly "generic" Mylan estradiol transdermal dot patches in the same strength, 0.025 mg. During the 4 1/2 weeks I used the Mylan product, I developed hot flashes, night sweats, brain fog and urinary tract infections. I could not understand what was wrong until I recalled that my symptoms began when I started the Mylan product. I found out that Vivelle Dots are still under patent. Mylan patented its own competing transdermal patch in order not to infringe the Novertis patent. It is NOT the same product. A return to Vivelle Dots solved my problem.”

1 / 10
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Lili · Taken for 1 to 6 months · February 20, 2021

For Postmenopausal Symptoms: “My biggest concern is that I am not getting the relief of post menopause even though I am using 0.1mg patch because the patch does not stay on your skin. I have been using the estradiol patch for many years. I was using Vivelle Dot until it was not covered by my insurance and switched to Mylan labs. It would be nice if these patches could stay on my skin to rate the effectiveness of the medication.”

2 / 10
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Happycat · June 12, 2019

For Postmenopausal Symptoms: “MYLAN ESTRADIOL PATCH 1.0 seems to Be ineffective! Suffering from menopausal symptoms due to a complete hysterectomy Booted off the good stuff ... MINIVELLE DOT ❤️. Due to change of insurance even though I have full coverage! Insurance won’t Pay the $450 cost for 3 month supply . I wonder what’s even on the MYLAN ESTRADIOL PATCH is it even real ?”

1 / 10
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June · Taken for 1 to 6 months · April 23, 2020

For Postmenopausal Symptoms: “I had the Sandoz patch and it was great - a nice, thin patch that I forget is there except that I feel much better. The next month, I got the Mylan patch that is covered by my provider. It is thicker, and catches just a little bit on the edges. More importantly, it leaves red marks underneath upon removing it, and small marks that look like burns around the edge. I've also seemed to have some itching around the patch while it is one. I will be switching back to Sandoz.”

8 / 10
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Ali · Taken for 1 to 6 months · October 9, 2020

For Postmenopausal Symptoms: “I have been on Vivelle Dot for 8 years. Love it and no issues at all. I cannot find it anymore and have checked several pharmacies. I had to switch to Mylan generic. Absolutely awful. It does not stick well and comes off. It leaves red marks on my skin and is itchy. I do not feel I am getting the same amount of hormones and my body can tell the difference. I have used it for 2 months. The patch is supposed to last 3 1/2 days and I am sometimes changing after 2 days. Not happy with this. I hope to find Vivelle again. I am looking for other options.”

3 / 10
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Switching patches · Taken for 1 to 6 months · June 6, 2020

For Oophorectomy: “I have been on the Mylan estradiol patch only since March 2020 and have patch-sized round burn like spots in every single place I’ve used this patch. The medication itself works fine for me but it hate the patch! It’s on the larger side and is thick and catches in clothing easily. If it gets wet at all it’ll peel right off. The material it’s made of holds moisture and halfway through the week it’s wet underneath no matter how long it has been since I’ve been in the water. I started putting tegaderm over it first thing but even still when I take it off it’s wet underneath and smells. It is unfortunately the only one my insurance will cover, however my dr is working in changing it to a combo patch. Hopefully insurance will approve it because I’m so tired of this one!”

4 / 10
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MrsSPT · August 23, 2016

For Postmenopausal Symptoms: “I was caught in a vicious cycle of soaking wet hot flash after soaking wet hot flash which caused me to become agitated which caused my heart to race ALL NIGHT LONG which then caused me to be irritable and I could barely focus during the day. My doctor started me on the estradiol patch .05 mg and within a few days I felt like a new person. I now go through the entire night maybe one minor hot flash and the resulting anxiety is gone. I sleep now better than I ever have. The only side effect I have noticed is that my breasts are a little tender but not enough to make me stop. If I wind up gaining a few pounds who cares I am a human being again.”

10 / 10
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Hot in Texas · Taken for 1 to 6 months · August 8, 2019

For Postmenopausal Symptoms: “I was using Vivelle Dot and then Minivelle for 10+ years. Due to the cost and no insurance, I switched to the generic patch. It does NOT work. The change in my estrogen levels was drastic...as if I wasn’t getting any at all. The hot flashes and night sweats returned. These patches are trash. I will be paying the outrageous price for Minivelle to get my hormones balanced again.”

1 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.