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User Reviews for Vagifem

Vagifem has an average rating of 6.3 out of 10 from a total of 76 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect.

Condition Avg. Rating Reviews Compare
Atrophic Vaginitis  
6.0
66 reviews 54 medications
Atrophic Urethritis  
7.8
10 reviews 46 medications
Summary of Vagifem reviews 6.3 76 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Vagifem

Gal · Taken for 1 to 2 years September 17, 2020

For Atrophic Vaginitis: “I left a comment in August regarding Vagifem and gave it 10/10 for curing my symptoms of repeated urinary tract infections but over the last few weeks since starting a new box of Vagifem I have noticed that for the first 2 days after using it I too am getting a stinging feeling in the vagina which also makes me feel like I have a urinary tract infection and tingling in the breasts which I have not experienced before. Reluctantly I have stopped the medication as these new symptoms are too uncomfortable and I am wondering if the manufacturer has changed the formula. Not happy.”

7 / 10
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Pookie · Taken for 10 years or more March 10, 2020

For Atrophic Vaginitis: “Does anyone know if any of the ingredients have changed recently? I have been using vagifem for almost 15 years once a week and never experienced any burning but recently out of the blue I have burning and cannot understand why as I am using the brand and not the generic as that caused horrible problems. It works great but not happy with the irritation. Thank you.”

8 / 10
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Lily · Taken for 10 years or more April 1, 2021

For Atrophic Urethritis: “I am 80 years old and I've been taking Vagifem for over 15 years since my surgery (Radical historectomy for uterine cancer). I trusted my doctor completely and have not had any problems with UTI's or vaginal dryness. I also use a KY-gel product after my shower and have no problem reaching a climax with masturbation, my only sexual release at my age. I also get Vagifem from Canadian Pharmacy for one-third the cost in the States. My younger sister could not tolerate Vagifem for many of the negative reports here, but she also didn't have cancer and is able to get relief from other meds. I really appreciate your comments and wish all the best to my sisters-at-large.”

10 / 10
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Wonder woman · Taken for less than 1 month March 18, 2021

For Atrophic Vaginitis: “I was prescribed Vagifem finally after a year of burning, painful sex and constant urine infections. Literally after 3 days the burning was 70% better and I actually enjoyed sex for the first time in ages ! Totally recommend Vagifem and I've had zero side affects . Still got every other peri menopause symptom but one less to deal with is a huge relief! Good luck ladies !”

9 / 10
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Lola F · Taken for 1 to 6 months May 9, 2021

For Atrophic Vaginitis: “I've been using vagifem for a few months now & definitely took several weeks for my symptoms to calm down. Before using this my entire vaginal area had become dry, hyper sensitive & sore & sex was so painful, vagifem has restored lubrication & feel like me again, so happy with results. Also have had no hot flashes since I started taking it & these were happening multiple times a night also not had a UTI since & have been having them every couple of months most of my adult life.”

10 / 10
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M · Taken for less than 1 month April 12, 2021

For Atrophic Vaginitis: “Worst 'medication' I've ever had. Horrific headache, couldn't even get up out of bed safely the day after one and only application, extreme nausea and dizziness, next few days spotting, vaginal pain, burning for the next two weeks until I took some acid regulators. Subsequently have been sleepless, extremely low on energy, cystitis, cold sore - basically everything saying the body's taken a beating. One pessary. Still battling it four weeks later. Never again.”

1 / 10
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Lou · Taken for 1 to 6 months February 9, 2021

For Atrophic Urethritis: “I am 43 and was sceptical about using Vagifem as did not have vagina dryness which is what it says it’s for, but I have had problems with ongoing leaking bladder since giving birth to very large baby and most recently consistent UTI . All I can say is thank goodness the female doctor I had told me to try this. I have not had any urine leakage at all since I been on it which is a miracle and no bladder infections. There so many women my age with this trouble it should be prescribed more for this it’s so good amazing !”

10 / 10
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Chads · Taken for 5 to 10 years May 7, 2021

For Atrophic Vaginitis: “I have been using Vagifem for many years now and although it's helped my symptoms a great deal, I find the recommended dosage of 1 pessary twice a week is not enough to keep me comfortable, however my dr refuses to prescribe me any extra. Imagine my surprise on visiting the Menopause Matters site to find many women on there are prescribed it 5x a week as twice a week doesn't relieve their symptoms. Apparently each Vagifem pessary used to be 25mcg (=50mcg a week) but for some unknown reason they reduced it to 10mcg per pessary (=20mcg a week)”

7 / 10
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sammie · Taken for less than 1 month April 3, 2020

For Atrophic Vaginitis: “I tried Vagifem for two weeks and while I think it probably helped with soreness inside and plumped things up, it also caused irritation of the uretha whereby I had a constant pressure, feeling like a need to wee all the time, burning and stinging inside. I couldn't live with it and it kept on waking me up at night. These symptoms started when I used vagifem and stopped when I stopped it. I really hope there is an alternative as I think for many vagifem is a miracle.”

5 / 10
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Mojo · Taken for less than 1 month February 7, 2020

For Atrophic Urethritis: “Have been having very painful cystitis and UTI's for over 4 years, I have been given numerous antibiotics over this time, after 1 to 2 weeks of finishing the course it was back again, was then kept on antibiotics full time, the specialist then suggested vagifem, the first one did sting, so didn't take more, then tried again 3 weeks later, and the pain & inflammation started to ease, after 4 Yr & antibiotics that didn't work I had found a breakthrough med, cannot believe at 57-62 age the GP never thought lack of estrogen could be the cause.”

10 / 10
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Blondie · Taken for 1 to 2 years June 2, 2019

For Atrophic Vaginitis: “Got prescribed Vagifem about 18 months ago and original hair loss was minimal. Had used this on and off in that time. More hair loss. Ouch. Used or started again a month ago. Experienced major hair loss and now have half as much as I used to. Scalp is visible in lots of areas. Will never use again and can only hope that hair will return.”

5 / 10
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MoBass · Taken for 5 to 10 years March 17, 2019

For Atrophic Vaginitis: “I had painful sex, vaginal bleeding, thrush for years due to a very early hysterectomy. I've been using Vagifem for seven years now and my life has completely turned around. I was first prescribed its use in the UK every time I had vaginal bleeding but a wonderful gynae in South Africa told me that I should be on small doses for the rest of my life.”

10 / 10
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Observant · Taken for 5 to 10 years June 17, 2020

For Atrophic Vaginitis: “Rectal wall bulging problem. Used Vagifem for many years and a couple of years in, started to suffer from repeated internal rectal wall bulges that caused major discomfort and required ligation via rubber banding by a Colorectal doctor every time - around 10 times. The rectal wall bulges kept recurring and I also experienced pressure in the lower abdomen when pressing down to pee. Stopped Vagifem over a year ago - have not had one single rectal wall bulge since!! I believe that Vagifem caused tissue, muscle and structural changes where it should not have.”

1 / 10
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Gal · Taken for 1 to 2 years August 18, 2020

For Atrophic Vaginitis: “I am in my late 60's and for the past few years have suffered at least 6-7 urinary tract infections a year. The urologist suggested using Vagifem as directed and apart from headaches and nausea for the first few days have not had any problems and my urinary tract infections have dropped significantly to 1-2 a year. I now only use it once a week and find this sufficient for keeping everything comfortable. I live in the UK so my prescriptions are free. I will continue using it for as long as my general practitioner is happy to prescribe it.”

10 / 10
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Ms · Taken for less than 1 month October 14, 2020

For Atrophic Vaginitis: “I’m 60 years old and have had multiple urinary tract infectionS over the years. My doctor just started me on the Vagifem 3 weeks ago as well as Progestrone oral tablets. In the last week the burning, itching and irritation is driving me crazy. I’m trying to deal with it and applying topical OTC creams as well as natural balms to try and calm my vagina area down. I’m going back to the doctor tomorrow as I can’t stand this any more. I was really hoping this medication would work for me, I wonder what the next step will be?”

1 / 10
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Pob · Taken for 5 to 10 years October 16, 2020

For Atrophic Vaginitis: “I have been on low dose (10mg) Vagifem for the past 9 years at least, I have always tolerated it well, but recently have experienced feelings of discomfort and I wonder if the manufacturing process of the pessary has changed?.”

10 / 10
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brody · Taken for less than 1 month December 31, 2019

For Atrophic Vaginitis: “Beware, ladies! I was reassured by my GP that topical oestrogen like Vagifem is so weak and mild it rarely causes side effects. But after taking Vagifem nightly for two weeks I started having dizzy spells. I took my own blood pressure and it was 153/85. Normally it is 121/74! I stopped taking the pills immediately, but 6 days later my blood pressure is still high and I am just hoping it goes down soon. This may be an uncommon side effect, I don't know, but the warning about strokes got me worried.”

1 / 10
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Mary Ann Williams · Taken for 2 to 5 years August 30, 2015

For Atrophic Vaginitis: “I used Vagifem as prescribed by my Gyn. I used this product as directed for on an off for a period of 2 years. I developed fallopian and ovarian cancer last year. I have had to have a hysterectomy-oophorectomy and excision of tumors. I feel that this was related to my taking the Vagifem even though my Gyn stated that this was a small dose of hormone and would not cause any adverse problems. I have since found that this is not the truth!”

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Bub · Taken for 2 to 5 years October 15, 2018

For Atrophic Urethritis: “Changed my life , was out of my mind with pain and cystitis constantly , never thought for one minute would get any improvement , but vagifem has helped immensely, but if I stop using them I go back to square one , so my gynaecologist said I need them for life , so pray they never stop producing them .”

9 / 10
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S Jean · Taken for 5 to 10 years June 18, 2016

For Atrophic Vaginitis: “I had been using vagifem for about 8 years and now have uterine cancer. I am having a hysterectomy next week as a result. When my cancer surgeon found out I was using vagifem tabs he immediately had me stop it.”

4 / 10
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Nicky · Taken for less than 1 month July 20, 2020

For Atrophic Vaginitis: “Use of Vagifem to address bladder frequency has caused significant irritation, itchiness and rawness around the vaginal area as well as thick white discharge. I have discontinued it and am attempting to treat these symptoms which have progressed to the urethra. Very discouraging as many women find it very helpful for post menopausal conditions .”

1 / 10
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kappin March 31, 2014

For Atrophic Vaginitis: “Vagifem truly changed my life. Intercourse was almost impossible for me before my doctor prescribed Vagifem. Intercourse felt like knives in my vagina and my tissues were so dry,raw, and painful that I was in constant pain. I have been using it now for about a month and the difference is unbelievable. No more pain or irritation. No side effects so far.”

9 / 10
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Linda · Taken for 5 to 10 years March 30, 2019

For Atrophic Vaginitis: “For those that may not be aware, you can purchase a 3 month supply of Vagifem through Canadian pharmacies for approximately $55. Have been using this approach for years and have never had a problem. If the cost of Vagifem is a problem for you, do yourself a favor and explore this alternative.”

10 / 10
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GoGirl62 February 17, 2014

For Atrophic Vaginitis: “No side effects and saw an immediate improvement, as well as a more peaceful state of mind, which may or may not be in my head, but I don't care. I felt great taking this medication, and it helped with the painful entry/sex that I was experiencing. Now, no problems!”

10 / 10
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Cherry · Taken for 1 to 6 months July 30, 2020

For Atrophic Vaginitis: “Great medicine. I was having recurrent UTIs and vaginal infections as a part of menopause. I have been on this medication for two months and have had no issues at all. I highly recommend it for vaginal atrophy”

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.