Vagifem Interactions
There are 258 drugs known to interact with Vagifem (estradiol topical), along with 17 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 33 are major, 209 are moderate, and 16 are minor.
- View all 258 medications that may interact with Vagifem
- View Vagifem alcohol/food interactions (2)
- View Vagifem disease interactions (17)
Most frequently checked interactions
View interaction reports for Vagifem (estradiol topical) and the medicines listed below.
- amlodipine
- aspirin
- Aspirin Low Strength (aspirin)
- atorvastatin
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- folic acid
- gabapentin
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- magnesium oxide
- melatonin
- meloxicam
- metformin
- Nexium (esomeprazole)
- omeprazole
- pantoprazole
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Vagifem alcohol/food interactions
There are 2 alcohol/food interactions with Vagifem (estradiol topical).
Vagifem disease interactions
There are 17 disease interactions with Vagifem (estradiol topical) which include:
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
Report options
More about Vagifem (estradiol topical)
- Vagifem consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (102)
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- Support group
- Drug class: estrogens
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Premarin
Premarin is used to treat symptoms of menopause such as hot flashes, and vaginal dryness. Learn ...
Estrace
Estrace (estradiol) is used to treat symptoms of menopause such as hot flashes and vaginal dryness ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Estrace Vaginal Cream
Estrace Vaginal Cream is used for atrophic urethritis, atrophic vaginitis
Prempro
Prempro (conjugated estrogens and medroxyprogesterone) is used to treat the symptoms of menopause ...
Conjugated estrogens
Conjugated estrogens systemic is used for abnormal uterine bleeding, atrophic urethritis, atrophic ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.