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User Reviews for Yuvafem

Yuvafem has an average rating of 3.1 out of 10 from a total of 98 ratings on Drugs.com. 18% of reviewers reported a positive experience, while 72% reported a negative experience.

Condition Avg. Rating Reviews Compare
Atrophic Vaginitis  
3.1
94 reviews 54 medications
Atrophic Urethritis  
2.3
4 reviews 46 medications
Summary of Yuvafem reviews 3.1 98 reviews

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Yuvafem

AE · October 23, 2019

For Atrophic Vaginitis: “Amneal had two companies producing their Yuvafem product. One company located in the USA (pink packaging) and the other in Denmark (blue packaging). I did not experience issues with the product manufactured in Denmark although the packaging was inferior to Vagifem. Amneal no longer uses the company in Denmark. The product in the pink packaging manufactured in the USA is as awful as the many negative reviews reflect. Burning and itching was the worse negative symptoms for me. Why is the FDA not aggressively addressing this. I have been battling with Amneal and it isn't a pleasant experience. I plan to escalate to the Attorney General of my state. Unfortunately too many politicians take money from the pharmaceutical companies so they do nothing to help stop the this abuse. I also take issue with the majority of insurance companies refusing to cover Vagifem or charge exhorbitant copays for a medication women need to maintain good health yet many have no problem with covering Viagra.”

1 / 10
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Westwind LIsa · November 7, 2018

For Atrophic Vaginitis: “I am a post-menopausal physician who began using Vagifem in 2011 after a total hysterectomy. I had absolutely no problems with Vagifem. It helped with my urogenital symptoms, such as dryness and urinary frequency. When Yuvafem came out, I was also changed to it via my mail-in pharmacy. I started experiencing a significant increase in vaginal irritation, vulvar dryness, and urinary frequency. I had been having vaginal discharge the day after I inserted the tablet with increased irritation and itching. I never had any significant discharge or irritation when using Vagifem. My symptoms got so bad that at the end of September I went back on brand-name Vagifem. My symptoms have been gradually improving. Given my experience, and the fact that so many others on this site and elsewhere have had a similar issues, I contacted the FDA. I also complained to them in regards to the poor packaging. I feel Yuvafem needs further investigation.”

1 / 10
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nurth · Taken for 2 to 5 years · August 30, 2020

For Atrophic Urethritis: “I used Vagifem for years & the only issue was occasional yeast infections at the beginning but the drug was effective for Vaginal Atrophy. Years later in an HMO that will only prescribe generics so forced to use Yuvafem. Initially it seemed okay but in the last 3 months I noticed symptoms of burning, itching and UTI returned. Simultaneously, I just read that Teva, the current generic manufacturer of Yuvafem that I'm using, has been indicted by U.S. Federal prosecutors for drug price-fixing along with other drug manufacturers. While they are only under investigation for price fixing, I hope the FDA is also investigating these companies to determine whether they are interfering with the drug formulation, i.e., cutting with fillers. Caveat emptor - while Vagifem is costly, we may be throwing money down the drain with generics that have filler instead of the drug.”

1 / 10
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Anonymous · Taken for 2 to 5 years · June 14, 2020

“The drug has helped my mild incontinence. The applicator and packaging is very bad for several Reasons 1. Plastic is overkill. Why plastic? I will throw away over 100 applicators and other plastic per year. I live near the ocean and cannot believe all the applicators for different female products that litter the ocean. Surely packaged in paper and with paper applicators Is the way to go. Please use your design brains to help us not ruin the environment anymore. If drinking straws are bad then your applicators with so much more rigid plastic are 100 times worse.”

5 / 10
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Westwind Lisa · March 14, 2019

For Atrophic Vaginitis: “**Update from my review dated November 7, 2018** I formally contacted the FDA in regards to what I felt was questionable efficacy of Yuvafem and its poor packaging (as compared to the brand-name Vagifem). The FDA contacted Amneal Pharmaceuticals and Amneal agreed to look into my complaint about Yuvafem's efficacy and its packaging. Amneal wanted me to provide them with the Yuvafem that I had leftover, which I did. It was to be sent back to them anonymously with just a brief history of my experience while on the medication. Since it was done anonymously, I won't have follow up in regards to my complaint, but at least the FDA responded to it and contacted them. I hope this helps others who have noticed a difference after being changed to Yuvafem, or who were started on it initially and continue to have symptoms consistent with atrophic vaginitis. If you feel the drug is not therapeutically beneficial to you, please contact the FDA to let them know. It can be done online.”

1 / 10
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Jazz · October 19, 2019

For Atrophic Vaginitis: “Switched to this product and it was horrible. I thought could have sex again and it was painful and got an infection. I used this as prescribed. This product does not melt properly at all. This product should not be used as saw 3 doctors for UTI and the embarrassment of being accused it was my partner fault. It was not. It was product. No woman should have to go through this. Did not want this product, it is insurance trying to cut corners. It cost them more in long run due to the number of doctor visits and 3 rounds of antibotics and one emergency visit. Sex was painful and vagina dry after using.. gyno said tablets not melting.. Please get rid of this product”

1 / 10
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LDn · March 7, 2017

For Atrophic Vaginitis: “I was a regular user of Vagifem and was very pleased with the results. It made sex comfortable again. I saw there was a generic available and tried it to try to save some money. This product is terrible. Everything about it is ten notches below Vagifem. You can't separate the foil packages. The applicator is sharp on the end. One of my doses was empty... and I pay $15 each. The pill does not dissolve inside you. When showering the next day I find the tablet just sitting up there undissolved. My vaginal dryness is back to where it was before beginning Vagifem. I am a 62 yr old woman with active sex life, my insurance will no longer pay for brand. I wish they would have more time before releasing. I hate everything about it.”

1 / 10
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NA · Taken for 6 months to 1 year · May 11, 2019

For Atrophic Vaginitis: “Yvuafem makes me spot and it gets worse over several days. First yellow and dark brown and then bloody discharge. My doctor checked me out. I’m fine so it’s definitely this medication. I did not have this problem with Vagifem and will tell my doctor the Vagifem is what I want. I am 63 years old. When I use the Yuvafem I have to wear a liner. Terrible medication and should be pulled from the market.”

2 / 10
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PamJ60 · Taken for less than 1 month · October 1, 2018

For Atrophic Vaginitis: “I don't understand all the negative comments. I have finished the two-week buildup phase and now starting on the twice-a week phase. No problem with the packaging. No problems with the pills falling out of the plunger. Pills do not "come out" the next day partially dissolved. No adverse effects from the medication. No problems at all. Even though my doctor said it would take about three months to reach maximum benefit, I already see an improvement. Great medication as far as I'm concerned.”

10 / 10
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irritated · Taken for 6 months to 1 year · May 7, 2020

For Atrophic Vaginitis: “I am so angry about this issue. Vagifem works, Yavafem does not. Like many of the others my insurance changed and now Vagifem is not covered. Yuvafem was like using nothing. Everything went right back to the way it was before weeks of treatment with vagifem (burning urination, dryness in vagina). I give up.”

1 / 10
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Whitney · June 22, 2019

For Atrophic Vaginitis: “I have used Vagifem for years without any issues whatsoever. It worked well and caused no problems. Then my insurance switched me to Yuvafem and it's been a nightmare. If I could give this drug a zero, I would have. Burning, redness, the feeling of having a UTI, then actually getting a UTI for the first time in 20 years, painful intercourse. The drug is completely ineffective for what it is supposed to do and it is causing plenty of problems. When I looked at the ingredients, I see that estradial is the same but the carrier ingredients are different, specifically Yuvafem uses propylene glycol. So, I could deal with the awful packaging if the drug actually worked and didn't cause so many problems, but it doesn't work and had me thinking I had some terrible infection for the last 3 weeks till my dr and I figured out it was the Yuvafem. I will be trying out the Estring and if I can't deal with it, I will be paying the big bucks and go back to the Vagifem.”

1 / 10
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Julie · Taken for 1 to 6 months · September 5, 2022

For Atrophic Vaginitis: “Not Pleased · Taken for less than 1 month · March 22, 2021 “... I experienced soreness, burning, itching, and increased need to urinate, plus greenish discharge. I’m discontinuing immediately." (Posted by NotPleased on March 22, 2021.) Ditto. I thought something was wrong with me until I started reading reviews for this product online.”

1 / 10
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Elana · January 13, 2020

For Atrophic Vaginitis: “First used Vagifem and seemed to work okay. Then like others, was switched to Yuvafem. Started having extreme itching, so washed regularly and applied moisturizer. Then burning started too and nothing helped to get over itchy, burning, and then burnt skin. I stopped yuvafem when spotting started. Skin began to clear up after two weeks. Then I used one tablet and extreme itching and skin was burnt again. I began to have pain in my joints, so bad that I entered a emergency room. I went off Yuvafem and 5 days later could walk again. After only one tablet, joint pain and burnt skin returned. My doctor could not find anything. He suggested that I was allergic to Yuvafem. So today decided to check reviews and found that Yuvafem is a dangerous drug.”

1 / 10
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Avra · Taken for 1 to 6 months · December 30, 2018

For Atrophic Vaginitis: “I used Vagifem for 4 years beginning when I was 68 years old. It was highly effective. I no longer had vaginal dryness. Sexual intercourse was pain and irritation free. About 4 months ago my insurance company stopped covering this drug. I was switched to Yuvafem. I agree with others that the packaging is much inferior to Vagifem’s. I have the same problem opening etc. But I could adjust to the inconvenience. However, I am going back on Vagifem because of how ineffective Yuvafem is. My labia and vagina are very dry again. Sexual intercourse is very painful. It is just like before I went on Vagifem. I feel Yuvafem is a waste of my money and has caused me pain and discomfort while promising to provide the same results as Vagifem. I plan to ask my physician to be my advocate with my insurance company about covering Vagifem again.”

1 / 10
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Deen · Taken for 1 to 2 years · April 13, 2019

For Atrophic Vaginitis: “1. Tablets fall out of applicator. Half the time I can see the tablet rattling around inside the plastic packaging before I even attempt to open it. 2. Packaging is impossible to separate. I have to use scissors. I'm only 52 and don't have arthritis--I can only imagine the struggle older women must have to open the packaging. 3. IT DOESN'T WORK AS WELL AS VAGIFEM! I've been using it for over a year now and find that my symptoms of dryness, burning, etc. fluctuate from package to package. I never had this problem on Vagifem.”

1 / 10
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Clj · Taken for 1 to 2 years · May 27, 2019

For Atrophic Vaginitis: “Yuvafem is horrible, I was on Vagifem but because of cost I can’t afford Vagifem but I won’t be using Yuvafem either. My symptoms of vaginal dryness and irritation came back full force using Yuvafem”

1 / 10
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Carol · Taken for 6 months to 1 year · October 13, 2018

For Atrophic Vaginitis: “Vagifem worked fine for years. Then insurance started sending Teva which was horrible. Applicator didn't work right and it was not effective, leaving me sore. Then insurance sent Uvafem. Applicators were better, but the medicine was not helping. In fact, everything was worse. I was sore all the time. Just recently my doctor prescribed brand only (Vagifem), but the insurance wouldn't release it until I used up the other. I argued with them and my doctor wouldn't get involved saying they had no ability to overrule the insurance company. Why does the insurance control our health?? Shouldn't the doctor's change in prescription be enough? Finally, a kindly pharmacist intervened and got me a prescription for Vagifem. I was so desperate I was willing to pay full price, but he was able to get it on my insurance. So glad to hear I am not alone, but wondering how we can get this changed. Insurance companies should not rule our health.”

1 / 10
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J.m.c · Taken for less than 1 month · August 26, 2017

For Atrophic Vaginitis: “Awful product. Was on Vagifem for 25 years, great product. Got switched to Yuvifem when it came out. Within a week I had horrible dryness and itching, vaginal tissue tearing and pain. It's like it's a placebo. Like others, I've asked my doctor to make my prescription brand only for Vagifem at much higher cost since it works. They need to rework Yuvifem so it actually is a working generic version. I emailed the manufacturer... everyone should.”

1 / 10
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Gloria · Taken for 2 to 5 years · April 12, 2019

For Atrophic Vaginitis: “This drug contains polyethlene glycol which can be an irritant! Read the label! No wonder I had constant burning whenever I used this drug. FDA needs to be alerted so other women will not be harmed by it. I had three biopsies of my skin in the vaginal area, which all came back as precancerous. It required constant medication just to keep it from getting worse, but it never completely healed this area. When I finally discovered the glycol and quit using it, my skin has returned to almost normal!”

1 / 10
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BlankyM · Taken for 6 months to 1 year · August 3, 2017

For Atrophic Vaginitis: “No problems with Vagifem. After using Yuvafem for a couple of weeks I started getting a discharge and feeling like I had an infection with burning and itching. It feels as if I am allergic to something in the drug. Going back to Vagifem.”

1 / 10
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Anagrey · Taken for 1 to 6 months · April 18, 2017

For Atrophic Vaginitis: “Awful product!!!!! I was excited that a generic was offered. The price was unbelievable compared to Vagifem but I am going back to the brand name. Price does not compare to comfort. I do not recommend this product.”

1 / 10
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Sam · Taken for 1 to 2 years · February 16, 2019

For Atrophic Vaginitis: “Can only use brand name Vagifem. Generic does not work at all. Packaging is horrible and symptoms of burning, itching, dryness, and feeling of a UTI, and constantly having to urinate are what happens when using generic. Had to go back to using Vagifem. Unfortunately the copay is really high until I meet my deductible. Insurance needs to offer this medication at a more affordable cost.”

1 / 10
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Jennufer · Taken for 6 months to 1 year · August 8, 2017

For Atrophic Vaginitis: “This medicine is a waste of money. I pay $136.00 for 8 of these pills. I follow the directions, using them at bedtime. This is perfect since I don't generally get up during the night to use the bathroom. However, when I wake up in the morning the first thing I do is use the bathroom. Why is that ding dong pill in the toilet? I have tried pushing it further back into the vaginal and its still the same results. I am skeptical of meds that lie in place for hours on. It has not improved my condition at all but empty my purse. Not refilling the prescription. This morning I found after not seeing the pill when I first went to the bathroom, I thought well it is finally working. WRONG! 9:00 bathroom break, what do I see? That stupid pill.”

1 / 10
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Rosie NC · Taken for 6 months to 1 year · September 17, 2017

For Atrophic Vaginitis: “As others have stated the packaging is awful. Pills don't stay on the applicator, or fall out after being inserted. Had to switch from Vagifem to Yuvafem in Jan because of insurance cost. Going to be 65 in Nov so I want to make sure I'll be able to afford Vagifem. On the generic, I've had a strange discharge I never had before, vaginal tearing during intercourse and more urgency. Thank you to all who have shared their experiences. I don't feel alone in this. Our doctors need to know there is a huge difference between the generic and original brand (Vagifem).”

1 / 10
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Anonymous · Taken for less than 1 month · January 19, 2017

For Atrophic Vaginitis: “My pharmacy filled my usual Vagifem prescription with the new generic form. It is like using a placebo. I am asking my doctor to prescribe brand only from now on, and will gladly pay the $275/month out of pocket until my insurance will cover it again. Terrible product!”

1 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.