Yuvafem and Itching: What Users Say

• AEa...
• October 23, 2019

For Atrophic Vaginitis "Amneal had two companies producing their Yuvafem product. One company located in the USA (pink packaging) and the other in Denmark (blue packaging). I did not experience issues with the product manufactured in Denmark although the packaging was inferior to Vagifem. Amneal no longer uses the company in Denmark. The product in the pink packaging manufactured in the USA is as awful as the many negative reviews reflect. Burning and itching was the worse negative symptoms for me. Why is the FDA not aggressively addressing this? I have been battling with Amneal and it isn't a pleasant experience. I plan to escalate to the Attorney General of my state. Unfortunately, too many politicians take money from the pharmaceutical companies so they do nothing to help stop this abuse. I also take issue with the majority of insurance companies refusing to cover Vagifem or charge exorbitant copays for a medication women need to maintain good health, yet many have no problem with covering Viagra."

• Wes...
• November 7, 2018

For Atrophic Vaginitis "I am a post-menopausal physician who began using Vagifem in 2011 after a total hysterectomy. I had absolutely no problems with Vagifem. It helped with my urogenital symptoms, such as dryness and urinary frequency. When Yuvafem came out, I was also changed to it via my mail-in pharmacy. I started experiencing a significant increase in vaginal irritation, vulvar dryness, and urinary frequency. I had been having vaginal discharge the day after I inserted the tablet with increased irritation and itching. I never had any significant discharge or irritation when using Vagifem. My symptoms got so bad that at the end of September I went back on brand-name Vagifem. My symptoms have been gradually improving. Given my experience, and the fact that so many others on this site and elsewhere have had similar issues, I contacted the FDA. I also complained to them regarding the poor packaging. I feel Yuvafem needs further investigation."

• nur...
• Taken for 2 to 5 years
• August 30, 2020

For Atrophic Urethritis "I used Vagifem for years, and the only issue was occasional yeast infections at the beginning, but the drug was effective for vaginal atrophy. Years later, in an HMO that will only prescribe generics, so forced to use Yuvafem. Initially, it seemed okay, but in the last 3 months, I noticed symptoms of burning, itching, and UTI returned. Simultaneously, I just read that Teva, the current generic manufacturer of Yuvafem that I'm using, has been indicted by U.S. Federal prosecutors for drug price-fixing along with other drug manufacturers. While they are only under investigation for price fixing, I hope the FDA is also investigating these companies to determine whether they are interfering with the drug formulation, i.e., cutting with fillers. Caveat emptor - while Vagifem is costly, we may be throwing money down the drain with generics that have filler instead of the drug."

• Ela...
• January 13, 2020

For Atrophic Vaginitis "First used Vagifem and seemed to work okay. Then, like others, was switched to Yuvafem. Started having extreme itching, so washed regularly and applied moisturizer. Then burning started too and nothing helped to get over itchy, burning, and then burnt skin. I stopped Yuvafem when spotting started. Skin began to clear up after two weeks. Then I used one tablet and extreme itching and skin was burnt again. I began to have pain in my joints, so bad that I entered an emergency room. I went off Yuvafem and 5 days later could walk again. After only one tablet, joint pain and burnt skin returned. My doctor could not find anything. He suggested that I was allergic to Yuvafem. So today, I decided to check reviews and found that Yuvafem is a dangerous drug."

• Bla...
• Taken for 6 months to 1 year
• August 3, 2017

For Atrophic Vaginitis "No problems with Vagifem. After using Yuvafem for a couple of weeks, I started getting a discharge and feeling like I had an infection with burning and itching. It feels as if I am allergic to something in the drug. Going back to Vagifem."

• Jmc...
• Taken for less than 1 month
• August 26, 2017

For Atrophic Vaginitis "Awful product. Was on Vagifem for 25 years, great product. Got switched to Yuvafem when it came out. Within a week I had horrible dryness and itching, vaginal tissue tearing and pain. It's like it's a placebo. Like others, I've asked my doctor to make my prescription brand only for Vagifem at much higher cost since it works. They need to rework Yuvafem so it actually is a working generic version. I emailed the manufacturer... everyone should."

• Jul...
• Taken for 1 to 6 months
• September 5, 2022

For Atrophic Vaginitis "Not Pleased · Taken for less than 1 month · March 22, 2021 “... I experienced soreness, burning, itching, and increased need to urinate, plus greenish discharge. I’m discontinuing immediately.” (Posted by NotPleased on March 22, 2021.) Ditto. I thought something was wrong with me until I started reading reviews for this product online."

• Sam...
• Taken for 1 to 2 years
• February 16, 2019

For Atrophic Vaginitis "Can only use brand name Vagifem. Generic does not work at all. Packaging is horrible, and symptoms of burning, itching, dryness, and feeling of a UTI, and constantly having to urinate are what happens when using generic. Had to go back to using Vagifem. Unfortunately, the copay is really high until I meet my deductible. Insurance needs to offer this medication at a more affordable cost."

• Con...
• December 9, 2020

For Atrophic Vaginitis "After 2 years of using BI pellets for HRT, had to choose an alternative and chose Yuvafem. Got Yuvafem but assumed it would work the same. Yuvafem application tool very uncomfortable to insert. About 2 weeks of using this product, had some discharge and itching. Thought - yeast infection and purchased a 3-day OTC. But didn't use it and the next day the symptoms were gone. After 2.5 months of using Yuvafem, recently started noticing what looked like a brownish discharge/spotting. Spoke to an ob-gyn's nurse, decided to wait till Monday and see if it's better. That night I had burning inside my abdomen. All weekend, felt like I had a UTI with abdominal and back pain. Monday, my GP doc did a urine test which was negative. After an additional 24 hours, the culture was still negative for UTI. At that point, started reading reviews about Yuvafem and found many similar stories to what I am experiencing. I will not use this product again and I hope the burning and internal pain go away soon!"

• Not...
• Taken for less than 1 month
• March 22, 2021

For Atrophic Vaginitis "After the 10 days of the first 14-day regimen of Yuvafem, I experienced soreness, burning, itching, and increased need to urinate, plus greenish discharge. I’m discontinuing immediately. I had the same symptoms when the pharmacy used to substitute generic birth control pills (Chryselle) for name brand pills, so there are obviously problems with the estrogen and/or fillers for both generic products."

• Kat...
• November 29, 2017

For Atrophic Vaginitis "I did well on Vagifem. Now on Yuvafem, the itching is ridiculous. It does help the vaginitis smell, but I am itching like mad! I thought I wasn’t doing it regularly enough or too much, so I tried both for a month each. Now I am calling the doctor to cancel this prescription. I can’t afford Vagifem right now, but THIS ISN'T WORKING. And yeah, the pills all fall out of the applicator and don’t seem to dissolve well. Plus, so much environmental waste!!"

• If...
• Taken for less than 1 month
• January 27, 2018

For Atrophic Vaginitis "Used Vagifem for many years, then the BIG SWITCH! Yuvafem is awful! I agree about the packaging being non-user friendly, but I learned to deal with it. The main issue for me is how much this product makes me smell 'down there.' Such a strong, pungent odor - ugh! Itching is a problem also. From now on, I will be paying the increased $$ for Vagifem - worth it to me, even though I resent this extreme increase the ins. companies are making us pay!"