Yuvafem and Vaginal Issues: What Users Say

• Wes...
• November 7, 2018

For Atrophic Vaginitis "I am a post-menopausal physician who began using Vagifem in 2011 after a total hysterectomy. I had absolutely no problems with Vagifem. It helped with my urogenital symptoms, such as dryness and urinary frequency. When Yuvafem came out, I was also changed to it via my mail-in pharmacy. I started experiencing a significant increase in vaginal irritation, vulvar dryness, and urinary frequency. I had been having vaginal discharge the day after I inserted the tablet with increased irritation and itching. I never had any significant discharge or irritation when using Vagifem. My symptoms got so bad that at the end of September I went back on brand-name Vagifem. My symptoms have been gradually improving. Given my experience, and the fact that so many others on this site and elsewhere have had similar issues, I contacted the FDA. I also complained to them regarding the poor packaging. I feel Yuvafem needs further investigation."

• LDn...
• March 7, 2017

For Atrophic Vaginitis "I was a regular user of Vagifem and was very pleased with the results. It made sex comfortable again. I saw there was a generic available and tried it to try to save some money. This product is terrible. Everything about it is ten notches below Vagifem. You can't separate the foil packages. The applicator is sharp on the end. One of my doses was empty, and I pay $15 each. The pill does not dissolve inside you. When showering the next day, I find the tablet just sitting up there undissolved. My vaginal dryness is back to where it was before beginning Vagifem. I am a 62-year-old woman with an active sex life, my insurance will no longer pay for the brand. I wish they would have more time before releasing. I hate everything about it."

• Avr...
• Taken for 1 to 6 months
• December 30, 2018

For Atrophic Vaginitis "I used Vagifem for 4 years, beginning when I was 68 years old. It was highly effective. I no longer had vaginal dryness. Sexual intercourse was pain and irritation-free. About 4 months ago, my insurance company stopped covering this drug. I was switched to Yuvafem. I agree with others that the packaging is much inferior to Vagifem’s. I have the same problem opening, etc. But I could adjust to the inconvenience. However, I am going back on Vagifem because of how ineffective Yuvafem is. My labia and vagina are very dry again. Sexual intercourse is very painful. It is just like before I went on Vagifem. I feel Yuvafem is a waste of my money and has caused me pain and discomfort while promising to provide the same results as Vagifem. I plan to ask my physician to be my advocate with my insurance company about covering Vagifem again."

• Clj...
• Taken for 1 to 2 years
• May 27, 2019

For Atrophic Vaginitis "Yuvafem is horrible. I was on Vagifem, but because of cost, I can’t afford Vagifem, but I won’t be using Yuvafem either. My symptoms of vaginal dryness and irritation came back full force using Yuvafem."

• MNG...
• Taken for 10 years or more
• July 10, 2017

For Atrophic Vaginitis "I had been using Vagifem for over 10 years. It definitely helped my vag atrophy symptoms as well as improved minor urine leakage issues. Six weeks ago, I was switched to Yuvafem. My first observation was with the packaging - the perforations between the individual units were nearly impossible to separate, and when I did, the foil cover of the adjacent units would break open. I use scissors now to cut them apart. Secondly, after about 4 weeks, I've noticed that vaginal irritation and urine leakage symptoms are returning. I'll use up my present 90-day supply and see how things go, but if symptoms worsen any more, I will ask my doc for a DAW (Dispense As Written) Vagifem prescription. I'll be willing to pay the significantly larger co-pay."

• Bml...
• Taken for 1 to 6 months
• October 2, 2018

For Atrophic Vaginitis "After using this medication for only 2 weeks, I called my doctor because of extremely severe vaginal burning. Even after modifying the treatment days, symptoms continued. I discontinued this TERRIBLE medicine, and all the discomfort, burning pain disappeared. So, for this reason, I will not use this drug."

• Tek...
• Taken for 1 to 6 months
• November 15, 2017

For Atrophic Vaginitis "I too was on Vagifem for about 1 1/2 years when my insurance switched me to Yuvafem. After 2 months, I was getting a lot of hot flashes, and the vaginal dryness started to come back. I did appeal to my insurance company, and they just approved for me to get the Vagifem back instead. I have a feeling my copay will go from $30 to $50, but it's worth it to get results. I had no issues with insertion or anything like that, but do believe either the pill dissolved too quickly or too slowly, and that is why I was having my symptoms return."

• Put...
• Taken for 2 to 5 years
• November 21, 2020

For Atrophic Vaginitis "I had fallopian tube cancer, and after a hysterectomy, chemo, and radiation, had terrible vaginal burning. Yuvafem seems to help, but the applicator upon insertion causes cuts and bleeding (which in my case causes quite a scare). My gynecological oncologist told me to insert it by hand. This is an extremely expensive drug. Couldn't it be made without the applicator to cut costs for those of us who cannot use the applicator, as long as the instructions included proper hygiene?"

• Hon...
• Taken for 6 months to 1 year
• December 27, 2020

For Atrophic Vaginitis "After using Yuvafem, I began feeling vaginal burning after urinating all the time and noticing hair loss, and feeling like I had a UTI. Very uncomfortable situation."