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Estradiol Patch and Sore Breasts: What Users Say

Sore breasts: mentioned by 4 users (2.4%)

Based on user experiences from 168 Estradiol Patch reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

itching 18.5%
hot flashes 16.1%
rash 7.1%
redness 6.5%
headaches 6.0%
night sweats 4.2%
insomnia 3.6%
sweating 3.0%
burning 2.4%
sore breasts 2.4%

Reviews for Estradiol Patch

Showing 4 reviews tagged with "sore breasts". Clear filters to view all 168 reviews.
Commonly mentioned side effects
  • Mrs...
  • August 23, 2016

For Postmenopausal Symptoms "I was caught in a vicious cycle of soaking wet hot flash after soaking wet hot flash, which caused me to become agitated, which caused my heart to race ALL NIGHT LONG, which then caused me to be irritable, and I could barely focus during the day. My doctor started me on the estradiol patch 0.05 mg, and within a few days, I felt like a new person. I now go through the entire night with maybe one minor hot flash, and the resulting anxiety is gone. I sleep now better than I ever have. The only side effect I have noticed is that my breasts are a little tender, but not enough to make me stop. If I wind up gaining a few pounds, who cares, I am a human being again."

10 / 10
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84 Report
  • Ano...
  • Taken for 10 years or more
  • August 26, 2021

For Postmenopausal Symptoms "I've been on this Estradiol patch since I had a full hysterectomy in 2003. No issues until my pharmacy ordered the Sandoz patch manufactured by 3M Drug Delivery Systems instead of the one from Noven Pharmaceuticals, Inc. Both are 0.0375 mg/day. The 3M patch is much larger, doesn't stick, causes a rash, causes hot flashes, bad breast tenderness and growth, migraines, and loss of sleep. I had to cut the patch since it was too much estrogen. The Noven patch seems to be identical to Vivelle Dot and works as directed for me. Beware of the manufacturer! I rate 3M a ZERO and Noven a 10."

2 / 10
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2 Report
  • kca...
  • Taken for 1 to 6 months
  • March 18, 2021

For Oophorectomy "Sandoz does not work. I am back to experiencing breast tenderness and hot flashes since switching to Sandoz. Sandoz does not stay on for more than two days. You can expect to go through an entire box in only 1.5 weeks. Huge disappointment."

1 / 10
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2 Report
  • San...
  • Taken for 1 to 6 months
  • July 13, 2022

For Postmenopausal Symptoms "Taking the Estradiol patch has caused me to have very frequent migraines when normally I don’t get one but now and then. It also doesn’t last the 3 to 3 1/2 days. The hair on my face starts popping out after a day and a half to 2 days. This causes an increase in hot flashes. Also, it has increased my desire for sex, causing nipples to be very sensitive. I have desires like a teenager."

4 / 10
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2 Report

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