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Conjugated Estrogens / Medroxyprogesterone Dosage

Medically reviewed by Drugs.com. Last updated on Mar 20, 2023.

Applies to the following strengths: 0.625 mg-2.5 mg; 0.45 mg-1.5 mg; 0.3 mg-1.5 mg; 0.625 mg-5 mg; biphasic

Usual Adult Dose for Osteoporosis

1 tablet orally once a day

Two regimens available, either

-OR-

Comments:

Use: Prevention of Postmenopausal Osteoporosis

Usual Adult Dose for Postmenopausal Symptoms

1 tablet orally once a day

Two regimens available, either

-OR-

Comments:

Use: Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause

Usual Adult Dose for Atrophic Urethritis

1 tablet orally once a day

Two regimens available, either

-OR-

Comments:

Use: Treatment of Moderate to Severe Vulvar and Vaginal Atrophy due to Menopause

Usual Adult Dose for Atrophic Vaginitis

1 tablet orally once a day

Two regimens available, either

-OR-

Comments:

Use: Treatment of Moderate to Severe Vulvar and Vaginal Atrophy due to Menopause

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Known liver dysfunction or disease: Use is contraindicated

Precautions

US BOXED WARNINGS: CARDIOVASCULAR DISORDERS, BREAST CANCER, ENDOMETRIAL CANCER, and PROBABLE DEMENTIA:
Estrogen Plus Progestin Therapy:

Estrogen-Alone Therapy:

CONTRAINDICATIONS:

Safety and efficacy have not been established in premenopausal women.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Missed dose: If a dose is missed, it should be taken as soon as remembered; if it is close to the next dose, skip the missed dose and resume normal schedule

General:

Monitoring:

Patient advice:
Read the US FDA-approved patient labeling (Patient Information).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.