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Abaloparatide Side Effects

Medically reviewed by Last updated on May 4, 2022.


Commonly reported side effects of abaloparatide include: dizziness and hypercalciuria. Other side effects include: nausea and palpitations. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to abaloparatide: subcutaneous solution

Side effects requiring immediate medical attention

Along with its needed effects, abaloparatide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking abaloparatide:

More common

  • Blood in the urine
  • constipation
  • depression
  • loss of appetite
  • loss of weight
  • muscle weakness
  • nausea or vomiting
  • pain in the bone, joint, back, arms, or legs
  • pain in the side, back, or stomach
  • thirst
  • unusual tiredness or weakness

Less common

  • Fast, irregular, pounding, or racing heartbeat or pulse

Incidence not known

  • Chest tightness
  • cough
  • difficulty swallowing
  • dizziness
  • fast heartbeat
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • trouble breathing

Side effects not requiring immediate medical attention

Some side effects of abaloparatide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • headache

Less common

  • Dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
  • feeling of constant movement of self or surroundings
  • sensation of spinning

Incidence not known

  • Diarrhea
  • full or bloated feeling
  • general feeling of discomfort or illness
  • itching, rash
  • lack or loss of strength
  • muscle spasms of the leg and back
  • pressure in the stomach
  • swelling of the stomach area
  • trouble sleeping
  • unusual drowsiness, dullness, or feeling of sluggishness

For Healthcare Professionals

Applies to abaloparatide: subcutaneous solution


Very common (10% or more): Common (1% to 10%): Orthostatic hypotension, tachycardia (e.g., sinus tachycardia), palpitations[Ref]


Very common (10% or more): Immunogenicity[Ref]


Very common (10% or more): Injection site redness (58%), injection site edema (10%)

Common (1% to 10%): Injection site pain[Ref]


Common (1% to 10%): Nausea, upper abdominal pain[Ref]


Very common (10% or more): Increased serum uric acid (25%)

Common (1% to 10%): Hypercalcemia[Ref]


Very common (10% or more): Hypercalciuria (20%)

Common (1% to 10%): Urolithiasis[Ref]

Nervous system

Very common (10% or more): Dizziness (10%)

Common (1% to 10%): Headache, vertigo[Ref]


1. "Product Information. Tymlos (abaloparatide)." Radius Health (2017):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.