Tymlos Side Effects

Generic name: abaloparatide

Medically reviewed by Drugs.com. Last updated on Nov 12, 2024.

Note: This document provides detailed information about Tymlos.

Applies to abaloparatide: subcutaneous solution Side Effects associated with abaloparatide. Some dosage forms listed on this page may not apply specifically to the brand name Tymlos.

Applies to abaloparatide: subcutaneous solution.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

This medicine may increase your risk of having osteosarcoma (bone cancer). This is more likely to occur if you have a history of radiation treatment involving your bones. Check with your doctor right away if you have bone pain that does not go away or a new soft tissue mass that is tender to palpation.

This medicine may cause some people to become dizzy or drowsy. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.

Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help. If this problem continues or gets worse, check with your doctor.

This medicine may increase levels of calcium in the blood and urine. High calcium in the urine may cause kidney stones. Call your doctor right away if you have blood in the urine, confusion, constipation, dry mouth, metallic taste, muscle weakness, nausea or vomiting, pain in the side, back, or stomach, or weight loss.

Serious side effects of Tymlos

Along with its needed effects, abaloparatide (the active ingredient contained in Tymlos) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking abaloparatide:

Other side effects of Tymlos

Some side effects of abaloparatide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to abaloparatide: subcutaneous solution.

General adverse events

The most common side effects resulting in discontinuation were nausea, dizziness, headache, and palpitations.

Cardiovascular

• Common (1% to 10%): Palpitations, tachycardia (including sinus tachycardia), orthostatic hypotension^[Ref]

Dermatologic

• Postmarketing reports: Pruritus, rash

Gastrointestinal

• Common (1% to 10%): Nausea, upper abdominal pain, abdominal distention, diarrhea
• Postmarketing reports: Abdominal distention, abdominal pain, constipation, diarrhea, vomiting^[Ref]

Hypersensitivity

• Postmarketing reports: Hypersensitivity and anaphylactic reaction

Immunologic

• Very common (10% or more): Immunogenicity^[Ref]

Local

• Very common (10% or more): Redness at injection site (58%), edema at injection site (11%), pain at injection site (10%)
• Common (1% to 10%): Contusion at injection site
• Postmarketing reports: Injection site bruising, hemorrhage^[Ref]

Metabolic

• Very common (10% or more): Increased serum uric acid (25%)
• Common (1% to 10%): Hypercalcemia^[Ref]

Nervous system

• Very common (10% or more): Dizziness (10%)
• Common (1% to 10%): Headache
• Postmarketing reports: Lethargy^[Ref]

Other

• Common (1% to 10%): Fatigue, vertigo
• Postmarketing reports: Asthenia, malaise

Psychiatric

• Postmarketing reports: Insomnia

Renal

• Very common (10% or more): Hypercalciuria (20%)
• Common (1% to 10%): Urolithiasis^[Ref]

Respiratory

• Postmarketing reports: Dyspnea

Musculoskeletal

• Common (1% to 10%): Arthralgia, bone pain
• Postmarketing reports: Bone pain, joint pain, back pain, extremity pain, leg and back muscle spasms

See also:

Frequently asked questions

• Can Tymlos cause bone cancer?
• How do you use Tymlos?

Further information

Tymlos side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer