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Prempro (conjugated estrogens / medroxyprogesterone) Drug Interactions

A total of 324 drugs are known to interact with Prempro (conjugated estrogens / medroxyprogesterone).

  • 26 major drug interactions
  • 269 moderate drug interactions
  • 29 minor drug interactions

Show all medications in the database that may interact with Prempro (conjugated estrogens / medroxyprogesterone).

Check for interactions

Type in a drug name to check for interactions with Prempro (conjugated estrogens / medroxyprogesterone).

Most frequently checked interactions

View interaction reports for Prempro (conjugated estrogens / medroxyprogesterone) and the medicines listed below.

  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Bufferin, Fasprin, Arthritis Pain, Easprin, Aspergum, Aspiritab, Halfprin, Empirin, Ascriptin Enteric, Aspirin Lite Coat, Aspi-Cor, Aspirtab, Ecotrin Adult Low Strength, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Entercote, St. Joseph Aspirin, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Bayer Aspirin Regimen, Heartline, Bayer Advanced Aspirin, Buffasal)
  • black cohosh (Menopause Support)
  • clonazepam (Klonopin, Klonopin Wafer)
  • Cymbalta (duloxetine)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • folic acid (Folvite, Folacin-800, FA-8, FaLessa)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • hydrochlorothiazide (HydroDIURIL, Microzide, Oretic, Esidrix, Ezide, Diaqua, Aquazide H, Hydro Par, Carozide, Loqua)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Levothyrox, Eltroxin, Euthyrox, Unithroid, Oroxine, Eutroxsig, Levo-T, L Thyroxine Roche, Novothyrox, Levotabs, Tirosint-Sol, Levotec, Evotrox)
  • Lipitor (atorvastatin)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • Nexium (esomeprazole)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Peri-DS (casanthranol / docusate)
  • simvastatin (Zocor, FloLipid)
  • Singulair (montelukast)
  • Synthroid (levothyroxine)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, ConZip, Ultram ER, Zydol, Tramahexal, Zamadol, Ryzolt, Tramal SR, Larapam SR, GenRx Tramadol, Tramahexal SR, Tramedo, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)

Prempro (conjugated estrogens / medroxyprogesterone) alcohol/food interactions

There are 6 alcohol/food interactions with Prempro (conjugated estrogens / medroxyprogesterone)

Prempro (conjugated estrogens / medroxyprogesterone) disease interactions

There are 25 disease interactions with Prempro (conjugated estrogens / medroxyprogesterone) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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