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Medications for Narcolepsy

Other names: Daytime sleep disorder; Excessive Sleepiness

About Narcolepsy

Narcolepsy is a sleep disorder associated with uncontrollable sleepiness and frequent daytime sleeping.

Drugs used to treat Narcolepsy

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Adderall 8.4 57 reviews
Rx C 2 X

Generic name: amphetamine / dextroamphetamine systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Provigil 6.6 90 reviews
Rx C 4

Generic name: modafinil systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Xyrem 7.7 90 reviews
Rx B 3 X

Generic name: sodium oxybate systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Nuvigil 6.6 88 reviews
Rx C 4

Generic name: armodafinil systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

modafinil 6.6 139 reviews
Rx C 4

Generic name: modafinil systemic

Brand name:  Provigil

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

sodium oxybate 7.7 96 reviews
Rx B 3 X

Generic name: sodium oxybate systemic

Brand name:  Xyrem

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Ritalin 7.2 30 reviews
Rx C 2 X

Generic name: methylphenidate systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Wakix 6.3 8 reviews
Rx N

Generic name: pitolisant systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

methylphenidate 7.6 59 reviews
Rx C 2 X

Generic name: methylphenidate systemic

Brand names:  Ritalin, Concerta, Methylin, Methylin ER …show all

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Xywav 6.7 3 reviews
Rx 3 X

Generic name: calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Dexedrine 8.4 15 reviews
Rx C 2 X

Generic name: dextroamphetamine systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Concerta 6.9 12 reviews
Rx C 2 X

Generic name: methylphenidate systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

dextroamphetamine 8.6 28 reviews
Rx C 2 X

Generic name: dextroamphetamine systemic

Brand names:  Dexedrine, Zenzedi, ProCentra

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

amphetamine / dextroamphetamine 8.3 83 reviews
Rx C 2 X

Generic name: amphetamine / dextroamphetamine systemic

Brand name:  Adderall

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

armodafinil 6.3 119 reviews
Rx C 4

Generic name: armodafinil systemic

Brand name:  Nuvigil

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Methylin 8.6 5 reviews
Rx C 2 X

Generic name: methylphenidate systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

amphetamine 7.0 2 reviews
Rx C 2 X

Generic name: amphetamine systemic

Brand name:  Evekeo

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

desvenlafaxine Off-label 9.0 1 review
Rx C N X

Generic name: desvenlafaxine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Methylin ER 9.0 1 review
Rx C 2 X

Generic name: methylphenidate systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

Zenzedi 10 1 review
Rx C 2 X

Generic name: dextroamphetamine systemic

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ProCentra Rate Add review
Rx C 2 X

Generic name: dextroamphetamine systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ephedrine Off-label 8.5 2 reviews
Rx C N

Generic name: ephedrine systemic

Drug class: vasopressors, decongestants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Evekeo 4.0 1 review
Rx C 2 X

Generic name: amphetamine systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

lisdexamfetamine Off-label 8.8 9 reviews
Rx C 2 X

Generic name: lisdexamfetamine systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off-label: Yes

Sunosi 4.4 21 reviews
Rx 4

Generic name: solriamfetol systemic

Drug class: miscellaneous central nervous system agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Topics under Narcolepsy

Learn more about Narcolepsy

IBM Watson Micromedex

Symptoms and treatments

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.