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Ephedrine Side Effects

For the Consumer

Applies to ephedrine: intravenous solution

Along with its needed effects, ephedrine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking ephedrine:

Incidence not known
  • Blurred vision
  • dizziness
  • fast, pounding, or irregular heartbeat or pulse
  • headache
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat

Some side effects of ephedrine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
  • Nausea or vomiting
  • restlessness

For Healthcare Professionals

Applies to ephedrine: compounding powder, injectable solution, intravenous solution, oral capsule

General

The most frequently reported side effects were nausea, vomiting, and tachycardia.[Ref]

Cardiovascular

Very rare (less than 0.01%): Myocardial infarction
Frequency not reported: Tachycardia, palpitations, reactive hypertension, bradycardia, ventricular ectopics, R-R variability, pallor, angina/anginal pain, hypertension, hypotension, extrasystole, arrhythmias, vasodilation with low blood pressure, flushing, impaired circulation to extremities[Ref]

Genitourinary

Frequency not reported: Difficult/painful urination, acute urinary retention[Ref]

Nervous system

Frequency not reported: Dizziness, headache, trembling, lightheadedness, tremor, sedation[Ref]

Respiratory

Frequency not reported: Dry nose, dry throat, shortness of breath, respiratory difficulty, dyspnea, respiratory depression[Ref]

Psychiatric

Frequency not reported: Restlessness, addiction, nervousness, anxiety, insomnia, mood/mental changes, fear, irritability, confusion, delirium, euphoria, psychotic states, tension, hallucinations[Ref]

Other

Frequency not reported: Fever, precordial pain, vertigo, tachyphylaxis, drug tolerance, drug dependence, weakness[Ref]

Gastrointestinal

Frequency not reported: Nausea, vomiting, dry mouth, mild epigastric distress, hypersalivation[Ref]

Metabolic

Frequency not reported: Hyperglycemia, anorexia[Ref]

Dermatologic

Frequency not reported: Sweating[Ref]

References

1. "Product Information. Akovaz (ePHEDrine)." Eclat Pharmaceuticals, Menomonee Falls,, WI.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. "Product Information. Ephedrine Sulfate (ephedrine)." Akorn Inc, Buffalo Grove, IL.

Some side effects of ephedrine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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