Ephedrine Alternatives Compared
Ephedrine | Sunosi | Sodium oxybate |
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Ephedrine | Sunosi (solriamfetol) | Sodium oxybate |
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Prescription and OTC
Prescribed for Adams-Stokes Syndrome, Asthma - acute, Hypotension, Narcolepsy, COPD - Acute, Myasthenia Gravis. ephedrine may also be used for purposes not listed in this medication guide. |
Prescription only
Sunosi is a once-daily medication that may be used to increase wakefulness in people with narcolepsy or obstructive sleep apnea (OSA). It can increase blood pressure and common side effects include... View more |
Prescription only
Prescribed for Idiopathic Hypersomnia, Cataplexy, Narcolepsy, Fibromyalgia. sodium oxybate may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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More about Ephedrine | More about Sunosi (solriamfetol) | More about Sodium oxybate | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Ephedrine has an average rating of 9.0 out of 10 from a total of 9 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 0% reported a negative effect. |
Sunosi has an average rating of 5.3 out of 10 from a total of 77 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 38% reported a negative effect. |
Sodium oxybate has an average rating of 7.8 out of 10 from a total of 123 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 13% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: ephedrine side effects in more detail. |
See also: Sunosi side effects in more detail. |
See also: sodium oxybate side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all ephedrine prices |
View all Sunosi prices |
View all sodium oxybate prices |
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Dosage Forms Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Akovaz, Bronkaid Max, Corphedra, Emerphed, Primatene Intermittent Asthma, Rezipres |
N/A |
Lumryz, Xyrem | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
11 hours |
7.1 hours |
1 hour |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 224 drugs are known to interact with ephedrine:
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A total of 81 drugs are known to interact with Sunosi:
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A total of 343 drugs are known to interact with sodium oxybate:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
N/A |
March 20, 2019 |
May 01, 2023 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.