Provigil Interactions
There are 521 drugs known to interact with Provigil (modafinil), along with 5 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 76 are major, 265 are moderate, and 180 are minor.
- View all 521 medications that may interact with Provigil
- View Provigil alcohol/food interactions (4)
- View Provigil disease interactions (5)
Most frequently checked interactions
View interaction reports for Provigil (modafinil) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- baclofen
- clonazepam
- Cymbalta (duloxetine)
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- Lyrica (pregabalin)
- metformin
- Nexium (esomeprazole)
- omeprazole
- prednisone
- Prozac (fluoxetine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Provigil alcohol/food interactions
There are 4 alcohol/food interactions with Provigil (modafinil).
Provigil disease interactions
There are 5 disease interactions with Provigil (modafinil) which include:
Report options
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
