Methylphenidate Interactions
There are 207 drugs known to interact with methylphenidate, along with 14 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 23 are major, 173 are moderate, and 11 are minor.
- View all 207 medications that may interact with methylphenidate
- View methylphenidate alcohol/food interactions (4)
- View methylphenidate disease interactions (14)
Most frequently checked interactions
View interaction reports for methylphenidate and the medicines listed below.
- Abilify (aripiprazole)
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Lexapro (escitalopram)
- Lexapro (escitalopram)
- Prozac (fluoxetine)
- Prozac (fluoxetine)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Wellbutrin XL (bupropion)
- Zoloft (sertraline)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Methylphenidate alcohol/food interactions
There are 4 alcohol/food interactions with methylphenidate.
Methylphenidate disease interactions
There are 14 disease interactions with methylphenidate which include:
- agitation
- cardiac disease
- glaucoma
- hypertension
- psychiatric disorders
- substance abuse
- tics
- hypertension
- seizures disorders
- liver disease
- renal dysfunction
- seizure disorders
- hematologic toxicity
- GI narrowing
Report options
More about methylphenidate
- methylphenidate consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (1,089)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: CNS stimulants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Adderall
Adderall (amphetamine and dextroamphetamine) is used to treat narcolepsy and ADHD. Includes side ...
Vyvanse
Vyvanse is a prescription stimulant used to treat ADHD in children and adults, and binge eating ...
Xywav
Xywav is used for the treatment of cataplexy and excessive daytime sleepiness (EDS) in patients ...
Strattera
Strattera (atomoxetine) is used to treat attention deficit hyperactivity disorder. Learn about side ...
Concerta
Concerta is used to treat attention deficit disorder (ADD) and attention deficit hyperactivity ...
Ritalin
Ritalin (methylphenidate) is used to treat attention deficit disorder (ADD) and narcolepsy ...
Focalin
Focalin (dexmethylphenidate) is used to treat attention deficit hyperactivity disorder (ADHD) ...
Dexmethylphenidate
Dexmethylphenidate is used for ADHD, auditory processing disorder
Amphetamine/dextroamphetamine
Amphetamine/dextroamphetamine is used for ADHD, fatigue, narcolepsy
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
