Solriamfetol Side Effects
Medically reviewed by Drugs.com. Last updated on Nov 28, 2021.
For the Consumer
Applies to solriamfetol: oral tablet
Side effects requiring immediate medical attention
Along with its needed effects, solriamfetol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking solriamfetol:
More common
Less common
- Agitation
- chest pain or discomfort
- cough
- fast, irregular, pounding, or racing heartbeat or pulse
- feeling jittery
- irritability
- restlessness
- tightness of the chest
- tremor
- trouble breathing
- trouble sleeping
Side effects not requiring immediate medical attention
Some side effects of solriamfetol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
- Clenching, gnashing, or grinding teeth
- constipation
- decreased weight
- diarrhea
- dizziness
- dry mouth
- increased sweating
- stomach pain
- vomiting
For Healthcare Professionals
Applies to solriamfetol: oral tablet
General
The more commonly reported adverse reactions have included headache, nausea, decreased appetite, insomnia, and anxiety.[Ref]
Cardiovascular
Increased systolic and diastolic blood pressure and heart rate occurred in a dose-dependent manner during clinical trials.
Common (1% to 10%): Palpitations, chest discomfort/pain
Frequency not reported: Increased blood pressure and heart rate
Psychiatric
Common (1% to 10%): Insomnia, anxiety (includes nervousness and panic attacks), irritability, jittery
Frequency not reported: Agitation, restlessness
Anxiety was more commonly reported at higher doses. Agitation and restlessness were reported in less than 2% of patients.
Gastrointestinal
Nausea, including vomiting, dry mouth, and vomiting were more common at higher doses. Bruxism and thirst were reported in less than 2% of patients.
Common (1% to 10%): Nausea (includes nausea and vomiting), dry mouth, constipation, diarrhea, abdominal pain
Frequency not reported: Bruxism, thirst
Metabolic
Decreased appetite was more common at higher doses. Decreased weight was reported in less than 2% of patients.
Common (1% to 10%): Decreased appetite
Frequency not reported: Decreased weight
Respiratory
Frequency not reported: Cough, dyspnea
Cough and dyspnea were reported in less than 2% of patients.
Nervous system
Headache was more common with higher doses. Disturbances in attention and tremor were reported in less than 2% of patients.
Very common (10% or more): Headache (16%)
Common (1% to 10%): Dizziness
Frequency not reported: Disturbances in attention, tremor
Dermatologic
Common (1% to 10%): Hyperhidrosis
Frequently asked questions
More about solriamfetol
- Drug interactions
- Dosage information
- During pregnancy or Breastfeeding
- Reviews (49)
- En español
- Drug class: miscellaneous central nervous system agents
Patient resources
- Other brands
- Sunosi
Professional resources
Related treatment guides
References
1. "Product Information. Sunosi (solriamfetol)." Jazz Pharmaceuticals, Palo Alto, CA.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.