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Xyrem (sodium oxybate) Drug Interactions

A total of 606 drugs (3714 brand and generic names) are known to interact with Xyrem (sodium oxybate).

  • 544 major drug interactions (3550 brand and generic names)
  • 62 moderate drug interactions (164 brand and generic names)

Show all medications in the database that may interact with Xyrem (sodium oxybate).

Check for interactions with Xyrem (sodium oxybate)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Xyrem (sodium oxybate)

Xyrem (sodium oxybate) alcohol/food Interactions

There are 3 alcohol/food interactions with Xyrem (sodium oxybate)

Xyrem (sodium oxybate) disease Interactions

There are 6 disease interactions with Xyrem (sodium oxybate) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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