Xyrem Interactions
There are 346 drugs known to interact with Xyrem (sodium oxybate), along with 6 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 244 are major, and 102 are moderate.
- View all 346 medications that may interact with Xyrem
- View Xyrem alcohol/food interactions (3)
- View Xyrem disease interactions (6)
Most frequently checked interactions
View interaction reports for Xyrem (sodium oxybate) and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- baclofen
- bupropion
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- gabapentin
- ibuprofen
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- melatonin
- metformin
- methylphenidate
- modafinil
- Nuvigil (armodafinil)
- omeprazole
- propranolol
- Provigil (modafinil)
- Ritalin (methylphenidate)
- Singulair (montelukast)
- tramadol
- trazodone
- venlafaxine
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
Xyrem alcohol/food interactions
There are 3 alcohol/food interactions with Xyrem (sodium oxybate).
Xyrem disease interactions
There are 6 disease interactions with Xyrem (sodium oxybate) which include:
- depression
- hx drug/alcohol abuse
- glaucoma
- liver disease
- sensitivity to salt intake
- sleep apnea/respiratory depression
Report options
More about Xyrem (sodium oxybate)
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- Reviews (108)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Sunosi
Sunosi (solriamfetol) is a prescription medicine used for the treatment of excessive sleepiness in ...
Adderall
Adderall (amphetamine and dextroamphetamine) is used to treat narcolepsy and ADHD. Includes side ...
Xywav
Xywav is used for the treatment of cataplexy and excessive daytime sleepiness (EDS) in patients ...
Concerta
Concerta is used to treat attention deficit disorder (ADD) and attention deficit hyperactivity ...
Ritalin
Ritalin (methylphenidate) is used to treat attention deficit disorder (ADD) and narcolepsy ...
Lumryz
Lumryz (sodium oxybate) is used for the treatment of patients with narcolepsy. Includes Lumryz side ...
Armodafinil
Armodafinil may be used to improve wakefulness in adults who are very sleepy due to narcolepsy ...
Amphetamine/dextroamphetamine
Amphetamine/dextroamphetamine systemic is used for ADHD, fatigue, narcolepsy
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
