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Xyrem Interactions

There are 341 drugs known to interact with Xyrem (sodium oxybate), along with 6 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 243 are major, and 98 are moderate.

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Most frequently checked interactions

View interaction reports for Xyrem (sodium oxybate) and the medicines listed below.

Xyrem alcohol/food interactions

There are 3 alcohol/food interactions with Xyrem (sodium oxybate).

Xyrem disease interactions

There are 6 disease interactions with Xyrem (sodium oxybate) which include:


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.