Skip to Content

Xyrem Prices, Coupons and Patient Assistance Programs

Xyrem (sodium oxybate) is a member of the miscellaneous anxiolytics, sedatives and hypnotics drug class and is commonly used for Cataplexy and Narcolepsy.

Xyrem Prices

This Xyrem price guide is based on using the discount card which is accepted at most U.S. pharmacies. The cost for Xyrem oral liquid (500 mg/mL) is around $4,514 for a supply of 180 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

A generic version of Xyrem has been approved by the FDA. However we either do not have pricing information for it, or it is not commercially available. More info: generic Xyrem availability

Oral Liquid

500 mg/mL Xyrem oral liquid
from $4,513.73 for 180 milliliters
Quantity Per unit Price
180 milliliters $25.08 $4,513.73

Important: When there is a range of pricing, consumers should normally expect to pay the lower price. However, due to stock shortages and other unknown variables we cannot provide any guarantee. Printable Discount Card

Print Now

The free Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions.

Please note: This is a drug discount program, not an insurance plan. Valid at all major chains including Walgreens, CVS Pharmacy, Target, WalMart Pharmacy, Duane Reade and 65,000 pharmacies nationwide.

Xyrem Coupons and Rebates

Xyrem offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Some offers may be printed right from a website, others require registration, completing a questionnaire, or obtaining a sample from the doctor's office.

Xyrem Coupon Program: Eligible patients may pay no more than $35 per prescription; for additional information contact the program at 866-997-3688.

Applies to:Xyrem
Number of uses:Unknown

Patient Assistance Programs for Xyrem

Patient assistance programs (PAPs) are usually sponsored by pharmaceutical companies and provide free or discounted medicines to low income or uninsured and under-insured people who meet specific guidelines. Eligibility requirements vary for each program.

Provider: Xyrem Patient Assistance Program

Elligibility requirements:

  1. Must have no prescription coverage for needed medication
  2. Not disclosed
  3. Not specified
  4. The patient must be a US citizen or legal resident.
  5. Both prescriber and patient must be registered with the XYREM REMS Program.

Applicable drugs:

  • Xyrem (sodium oxybate) Oral Solution