Xyrem Alternatives Compared
Xyrem (sodium oxybate) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Adderall (amphetamine / dextroamphetamine) |
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Xyrem (sodium oxybate) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Adderall (amphetamine / dextroamphetamine) |
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Prescription only
Xyrem is a Schedule III controlled substance when prescribed to treat narcolepsy; however, there is a high risk of abuse associated with it and people who misuse it or sell it to other people are... View more |
Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
Prescription only
Adderall is a combination of four different amphetamine salts and may be used to improve attention, focus, or reduce impulsive behaviors in children over the age of 3 and adults with ADHD. It can... View more |
Related suggestions Narcolepsy
Popular comparisons
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More about Xyrem (sodium oxybate) | More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | More about Adderall (amphetamine / dextroamphetamine) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Xyrem has an average rating of 7.7 out of 10 from a total of 108 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 14% reported a negative effect. |
Xywav has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 13% reported a negative effect. |
Adderall has an average rating of 7.4 out of 10 from a total of 504 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 17% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
Generic Availability | ||||||||||||||||||||||||||
Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Xyrem prices |
View all Xywav prices |
View all Adderall prices |
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Dosage Forms Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Other sodium oxybate brands include: Lumryz |
N/A |
Other amphetamine / dextroamphetamine brands include: Adderall XR, Mydayis | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
1 hour |
0.66 hours |
34 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 344 drugs are known to interact with Xyrem:
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A total of 344 drugs are known to interact with Xywav:
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A total of 220 drugs are known to interact with Adderall:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
July 17, 2002 |
July 21, 2020 |
January 19, 1960 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.