Comparing Sunosi vs Xyrem
| Sunosi | Xyrem |
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| Sunosi (solriamfetol) | Xyrem (sodium oxybate) |
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Prescription only
Sunosi is a once-daily medication that may be used to increase wakefulness in people with narcolepsy or obstructive sleep apnea (OSA). It can increase blood pressure and common side effects include... View more |
Prescription only
Xyrem is a schedule III controlled substance when prescribed to treat narcolepsy; however, there is a high risk of abuse associated with it and people who misuse it or sell it to other people are... View more |
Related suggestions Popular comparisons
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| More about Sunosi (solriamfetol) | More about Xyrem (sodium oxybate) | ||||||||||||||||
| Generic Status | |||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | |||||||||||||||||
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Sunosi has an average rating of 4.8 out of 10 from a total of 65 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 45% reported a negative effect. |
Xyrem has an average rating of 7.7 out of 10 from a total of 108 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 14% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: Sunosi side effects in more detail. |
Common side effects include:
See also: Xyrem side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Sunosi prices |
View all Xyrem prices and generic prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other sodium oxybate brands include: Lumryz | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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7.1 hours |
1 hour |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 81 drugs are known to interact with Sunosi:
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A total of 339 drugs are known to interact with Xyrem:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 20, 2019 |
July 17, 2002 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.