Sunosi and High Blood Pressure: What Users Say

• jwa...
• November 3, 2019

For Narcolepsy "I got the free trial of 15 Sunosi pills. When I started using it, I didn't feel any better, still felt very tired. On the 2nd day of use, I started getting a bad headache and still felt really tired. I also checked my blood pressure, it was starting to get higher than normal, and my stomach was starting to bother me. After the 3rd day, my stomach got worse, still had a bad headache, and blood pressure was getting higher, some slight chest pain. So after that, I stopped taking it, and now it's been a week since I have been off of it, and no headache or stomach problems, and blood pressure is down. The only thing I know is all the drugs that I have taken for narcolepsy had bad side effects, and they all seem to be a bandage to fix the problem. I hate all of these meds because no one knows what damage you're doing to your body taking these meds, that's why none of this stuff is good for you."

• Coc...
• Taken for 1 to 6 months
• December 31, 2019

For Narcolepsy "I was given 75 mg Sunosi for my narcolepsy. On the positive side, I can tell the difference in energy, concentration, motivation, and productivity, and there is a decreased need for a midday nap. Negative: this drug causes major heart issues. I have atrial fibrillation, and I cannot take this medicine regularly as it increases my heart rate to 120 and raises my blood pressure. However, I try to take it once in a while if I have a commitment or something important to do, like running errands or needing to go somewhere. I am on Xyrem 4.5 for narcolepsy with excessive daytime sleepiness, which, although it helps me sleep about 6-7 hours, no longer helps me wake up refreshed as it did the first time I tried it. I also take Doxepin to sleep longer, but it leaves me feeling too tired the next day and counteracts the effect of a good night's sleep. I take a nap in the afternoon, except on the day when I take Sunosi."

• Nad...
• Taken for 1 to 6 months
• July 26, 2022

For Narcolepsy "I suffer from narcolepsy. When I used Sunosi for the first time, I can say it was effective from the first hour! That was like magic! But when I had to wake up so early at 5 a.m., it wasn't enough for the rest of the day, I was getting very tired in the middle of the day. I contacted my doctor, and he told me to double the dose from 75 mg to 150 mg if it wasn't enough for the rest of the day. But on the contrary, it got worse, and after 2 weeks of 150 mg of Sunosi, I felt as if the effect had become reversed! So he told me to return to 75 mg. Now I feel like a normal person, there are some days when I wake up late, so I don't take Sunosi to avoid staying up at night, but at other times when I use it, I can do my daily activities normally without having to sleep all day. For me, I didn't see any noticeable side effects from it, such as high blood pressure, that I monitored before and after using the drug for 10 days, and nothing happened so far. I have been using it for about 6 months."

• Fro...
• Taken for 1 to 6 months
• August 2, 2021

For Obstructive Sleep Apnea/Hypopnea Syndrome "I’ve been taking Sunosi for a month. I started at 37.5 mg and worked up to 150 mg. Sunosi has been keeping me awake during the day, but both my heart rate and BP are elevated. Insomnia is also becoming a problem. My doc lowered my dose to 75 mg, but I still have elevated heart rate and BP. I’ll probably have to stop the medication. Disappointing! I had the same problem with Nuvigil and Provigil."

• Ano...
• Taken for 1 to 2 years
• April 12, 2025

"I’m on half a dose of 75, so 37.5. It works well for about 5-6 hours, so I have to take it later in the day than you would think. After it wears off, I’m so exhausted. While it’s active in my system, I’m hot and feel like I’m going to explode physically. I’m assuming it’s high blood pressure. It also makes my heart beat fast. I will continue to use it because the benefits outweigh the cons."

• Lon...
• Taken for 1 to 6 months
• January 26, 2020

For Narcolepsy "This medication raises my blood pressure, and I felt like I had stroke symptoms on my total left side. My pressure was 189/114. Even half a tab made no difference."