Modafinil Interactions
There are 521 drugs known to interact with modafinil, along with 5 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 76 are major, 265 are moderate, and 180 are minor.
- View all 521 medications that may interact with modafinil
- View modafinil alcohol/food interactions (4)
- View modafinil disease interactions (5)
Most frequently checked interactions
View interaction reports for modafinil and the medicines listed below.
- Abilify (aripiprazole)
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall (amphetamine / dextroamphetamine)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Lexapro (escitalopram)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- Synthroid (levothyroxine)
- Synthroid (levothyroxine)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Vyvanse (lisdexamfetamine)
- Wellbutrin XL (bupropion)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Modafinil alcohol/food interactions
There are 4 alcohol/food interactions with modafinil.
Modafinil disease interactions
There are 5 disease interactions with modafinil which include:
Report options
More about modafinil
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- During pregnancy
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Adderall
Adderall (amphetamine and dextroamphetamine) is used to treat narcolepsy and ADHD. Includes side ...
Concerta
Concerta is used to treat attention deficit disorder (ADD) and attention deficit hyperactivity ...
Xywav
Xywav is used for the treatment of cataplexy and excessive daytime sleepiness (EDS) in patients ...
Ritalin
Ritalin (methylphenidate) is used to treat attention deficit disorder (ADD) and narcolepsy ...
Provigil
Provigil promotes wakefulness and is used to treat excessive daytime sleepiness caused by ...
Armodafinil
Armodafinil may be used to improve wakefulness in adults who are very sleepy due to narcolepsy ...
Amphetamine
Amphetamine is a stimulant and is used to trat narcolepsy and attention deficit disorder. Includes ...
Amphetamine/dextroamphetamine
Amphetamine/dextroamphetamine is used for ADHD, fatigue, narcolepsy
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
