Modafinil Alternatives Compared
| Modafinil | Sunosi (solriamfetol) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) |
|
|---|
| Modafinil | Sunosi (solriamfetol) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) |
|
|||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Prescription only
Prescribed for Chronic Fatigue Syndrome, ADHD, Fatigue, Depression, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Shift Work Sleep Disorder, Idiopathic Hypersomnia. Modafinil may also be... View more |
Prescription only
Sunosi is a once-daily medication that may be used to increase wakefulness in people with narcolepsy or obstructive sleep apnea (OSA). It can increase blood pressure and common side effects include... View more |
Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
Related suggestions |
|||||||||||||||||||||||
| More about Modafinil | More about Sunosi (solriamfetol) | More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
|
Modafinil has an average rating of 7.3 out of 10 from a total of 536 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect. |
Sunosi has an average rating of 5.4 out of 10 from a total of 81 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 36% reported a negative effect. |
Xywav has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 13% reported a negative effect. |
||||||||||||||||||||||||
| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Modafinil side effects |
View all Sunosi side effects |
View all Xywav side effects |
||||||||||||||||||||||||
| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
|
Lower cost generic |
||||||||||||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Modafinil prices |
View all Sunosi prices |
View all Xywav prices |
||||||||||||||||||||||||
| Dosage Forms | ||||||||||||||||||||||||||
|
|
|
||||||||||||||||||||||||
| Brand Names | ||||||||||||||||||||||||||
| Provigil |
N/A |
N/A |
||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
|
15 hours |
7.1 hours |
0.66 hours |
||||||||||||||||||||||||
| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
|
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
||||||||||||||||||||||||
| Pregnancy Category | ||||||||||||||||||||||||||
|
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
||||||||||||||||||||||||
| Drug Interactions | ||||||||||||||||||||||||||
|
A total of 521 drugs are known to interact with Modafinil:
|
A total of 81 drugs are known to interact with Sunosi:
|
A total of 346 drugs are known to interact with Xywav:
|
||||||||||||||||||||||||
| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
|
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
|
||||||||||||||||||||||||
| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
|
December 24, 1998 |
March 20, 2019 |
July 21, 2020 |
||||||||||||||||||||||||
| WADA Class View classifications | ||||||||||||||||||||||||||
|
N/A |
||||||||||||||||||||||||||
| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Xywav
Xywav is used for the treatment of cataplexy and excessive daytime sleepiness (EDS) in patients ...
Sunosi
Sunosi (solriamfetol) is a prescription medicine used for the treatment of excessive sleepiness in ...
Lumryz
Lumryz (sodium oxybate) is used for the treatment of patients with narcolepsy. Includes Lumryz side ...
Adderall
Adderall (amphetamine and dextroamphetamine) is used to treat narcolepsy and ADHD. Includes side ...
Mounjaro
Mounjaro (tirzepatide) is FDA-approved to manage type 2 diabetes in adults. It lowers blood sugar ...
Zepbound
Zepbound (tirzepatide) is an FDA-approved weekly injection for weight loss and obstructive sleep ...
Concerta
Concerta is used to treat attention deficit disorder (ADD) and attention deficit hyperactivity ...
Ritalin
Ritalin (methylphenidate) is used to treat attention deficit disorder (ADD) and narcolepsy ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.